| 1 |
中国青年创新促进会会员
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奖励 |
黄洵| |
| 2 |
A Mannich/Cyclization Cascade Process for the Asymmetric Synthesis of Spirocyclic Thioimida-zolidinexoindoles
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期刊论文 |
Yu Zhou|Dong Zhang|Jinyi Xu|Hong Liu| |
| 3 |
Design, Synthesis, and Biological Evaluation of Indoline and Indole Derivatives as Potent and Selective α1A-Adrenoceptor Antagonists.
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期刊论文 |
Yu Zhou|Jiang Wang|Xin Xie|Hong Liu| |
| 4 |
Design, synthesis and evaluation of benzo[a]thieno[3,2-g]quinolizines as novel l-SPD derivatives possessing dopamine D1, D2 and serotonin 5-HT1A multiple action profiles
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期刊论文 |
Lin Guo|Yu Zhou|Xuechu Zhen|Hong Liu| |
| 5 |
Design, synthesis and biological evaluation of novel 4-anilinoquinazolines with C-6 urea-linked side chains as inhibitors of the epidermal growth factor receptor
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期刊论文 |
Jian Ding|Hualiang Jiang|Hua Xie|Hong Liu| |
| 6 |
第六届全国优秀科技工作者
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奖励 |
柳红| |
| 7 |
Discovery of two aminoglycoside antibiotics as inhibitors targeting the menin-mixed lineage leukaemia interface
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期刊论文 |
Kong, Xiangqian|Jiang, Hualiang|Huang, Jiandong|Luo, Cheng| |
| 8 |
De Novo Design, Synthesis and Evaluation of Benzylpiperazine Derivatives as Highly Selective Binders of Mcl-1
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期刊论文 |
Li, Jingquan|Wang, Hui|Liu, Hong|Wang, Renxiao| |
| 9 |
A Simple Copper-Catalyzed One-Pot Synthesis of Indolo[1,2-a]quinazoline
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期刊论文 |
Chunpu Li|Lei Zhang|Shuangjie Shu|Hong Liu| |
| 10 |
The facile construction of the phthalazin-1(2H)-one scaffold via copper-mediated C-H(sp(2))/C-H(sp) coupling under mild conditions
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期刊论文 |
Zhu, Wei|Wang, Bao|Zhou, Shengbin|Liu, Hong| |
| 11 |
Asymmetric One-Pot Sequential Mannich/Hydroamination Reaction by Organo- and Gold Catalysts: Synthesis of Spiro[pyrrolidin-3,2 '-oxindole] Derivatives
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期刊论文 |
Ji, Xun|Jiang, Hualiang|Yao, Zhu-Jun|Liu, Hong| |
| 12 |
Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclopenta[b]pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
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期刊论文 |
Zhao, Linxiang|Gao, Zhaobing|Jiang, Hualiang|Liu, Hong| |
| 13 |
Site-specific indolation of proline-based peptides via copper(II)-catalyzed oxidative coupling of tertiary amine N-oxides
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期刊论文 |
Zhang, Dengyou|Zhou, Shengbin|Gao, Feng|Liu, Hong| |
| 14 |
Discovery and Mechanism Study of SIRT1 Activators that Promote the Deacetylation of Fluorophore-Labeled Substrate
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期刊论文 |
Chen, Kaixian|Jiang, Hualiang|Liu, Hong|Liu, Dongxiang| |
| 15 |
第十四届中国青年科技奖
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奖励 |
柳红| |
| 16 |
Palladium-Catalyzed Picolinamide-Directed Coupling of C(sp2)-H and C(sp2)-H: a Straightforward Approach to Quinolinone and Pyridone Scaffolds
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期刊论文 |
Yong Nian|Yu Zhou|Hualiang Jiang|Hong Liu| |
| 17 |
Novel 5-(benzyloxy)pyridin-2(1H)-one derivatives as potent c-Met inhibitors
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期刊论文 |
Jiang, Hualiang|Luo, Cheng|Geng, Meiyu|Liu, Hong| |
| 18 |
Nickel-Catalyzed ortho-C-H Thiolation of N-Benzoyl alpha-Amino Acid Derivatives
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期刊论文 |
Zhang, Dengyou|Li, Shuangjie|Wang, Jiang|Liu, Hong| |
| 19 |
Identification of Novel Thiadiazoloacrylamide Analogues as Inhibitors of Dengue-2 Virus NS2B/NS3 Protease
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期刊论文 |
Yan Ye|Jing Chen|Xu Shen|Hong Liu| |
| 20 |
2014 年朱李月华优秀教师奖
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奖励 |
柳红| |
| 21 |
Rapid Generation of Privileged Substructure-Based Compound Libraries with Structural Diversity and Drug-Likeness
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期刊论文 |
Zheng, Mingyue|Zhao, Fei|Zhai, Yun|Liu, Hong| |
| 22 |
Au(I)/Ag(I)-Catalyzed Cascade Approach for the Synthesis of Benzo[4,5]imidazo[1,2-c]pyrrolo[1,2-a]quinazolinones
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期刊论文 |
Wang, Jinfang|Zhao, Linxiang|Jiang, Hualiang|Liu, Hong| |
| 23 |
Recyclable Ligands for the Non-Enzymatic Dynamic Kinetic Resolution of Challenging -Amino Acids
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期刊论文 |
Moriwaki, Hiroki|Kawashima, Aki|Soloshonok, Vadim A.|Liu, Hong| |
| 24 |
Asymmetric Synthesis of Aromatic and Hetero-Aromaticα-Amino Acids Using Recyclable Axially Chiral Ligand
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期刊论文 |
Aki Kawashima,|Hiroki Moriwaki|Vadim A. Soloshonok|Hong Liu| |
| 25 |
Structure-Based Design and Synthesis of C-1- and C-4-Modified Analogs of Zanamivir as Neuraminidase Inhibitors
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期刊论文 |
Tang, Wei|Seong, Baik-Lin|Jiang, Hualiang|Liu, Hong| |
| 26 |
Asymmetric Synthesis of Chiral Heterocyclic Amino Acids via the Alkylation of the Ni(II)-complex of Glycine and Alkyl Halides
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期刊论文 |
Hui Chen|Jiang Wang|Shengbin Zhou|Hong Liu| |
| 27 |
Synthesis and Evaluation of Anti-HIV-1 Activities of Novel7-Hydroxy-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-4-carboxylate Derivatives
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期刊论文 |
Hong Liu|Xing-Jie Zhang|Yongtang Zheng|Ronghua Luo| |
| 28 |
Asymmetric Michael Addition of N-tert-Butanesulfinyl lmidate with alpha,beta-Unsaturated Diesters: Scope and Application to the Synthesis of Indanone Derivatives
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期刊论文 |
Zhang, Lei|Li, Zeng|Chen, Xianjie|Liu, Hong| |
| 29 |
gamma-Carbon Activation through N-Heterocyclic Carbene/Bronsted Acids Cooperative Catalysis: A Highly Enantioselective Route to delta-Lactams
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期刊论文 |
Shuangjie Shu|Shenchao Jiao|Yu Zhou|Hong Liu| |
| 30 |
Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors
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期刊论文 |
Yinchun Ji|Xiaoyan Chen|Meiyu Geng|Hong Liu| |
| 31 |
Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets
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期刊论文 |
Huang, Ming|Geng, Meiyu|Spiegel, Sarah|Luo, Cheng| |
| 32 |
Palladium-Catalyzed C2-Acylation of Indoles with α-Diketones Assisted by the Removable N-(2-Pyrimidyl) Group
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期刊论文 |
Wei Zhu|Shuangjie Shu|Xiaoming Wu|Hong Liu| |
| 33 |
Copper-mediated C-H(sp(2))/C-H(sp(3)) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold
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期刊论文 |
Zhu, Wei|Zhang, Dengyou|Yang, Nan|Liu, Hong| |
| 34 |
Enantioselective Synthesis of 2-Substitued-Tetrahydroisoquinolin-1-yl Glycine Derivatives via Oxidative Cross-Dehydrogenative Coupling of Tertiary Amines and Chiral Nickel(II) Glycinate
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期刊论文 |
Jiang Wang|Daizong Lin|Fei Zhao|Hong Liu| |
| 35 |
FTY720 Induces Apoptosis of M2 Subtype Acute Myeloid Leukemia Cells by Targeting Sphingolipid Metabolism and Increasing Endogenous Ceramide Levels
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期刊论文 |
Jiang, Hualiang|Chen, Sai-Juan|Luo, Cheng|Li, Keqin Kathy| |
| 36 |
Highly selective intramolecular addition of C-N and S-N bonds to alkynes catalyzed by palladium: a practical access to two distinct functional indoles
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期刊论文 |
Zhao, Liang|Chen, Liang|Wang, Jiang|Liu, Hong| |
| 37 |
Direct access to pyrido/pyrrolo[2,1-b]quinazolin-9(1H)-ones through silver-mediated intramolecular alkyne hydroamination reactions
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期刊论文 |
Linxiang Zhao|Dan Liu|Yu Zhou|Hong Liu| |
| 38 |
Sphingosine 1-phosphate Receptor 2 Signaling Suppresses Macrophage Phagocytosis and Impairs Host Defense against Sepsis
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期刊论文 |
Liu, Hong|Zhao, Bing|Dai, KeZhi|Fang, XiangMing| |
| 39 |
Selective Synthesis of 5,6-Dihydroindolo[1,2-a]quinoxalines and 6,7-Dihydroindolo[2,3-c]quinolines by Orthogonal Copper and Palladium Catalysis
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期刊论文 |
Zheng, Mingyue|Zhai, Yun|Wang, Jiang|Liu, Hong| |
| 40 |
Discovery and Optimization of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Pharmacophore- and Docking-Based Virtual Screening
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期刊论文 |
Jiang, Hualiang|Lu, Wencong|Liu, Hong|Luo, Cheng| |
| 41 |
Metadynamics Simulation Study on the Conformational Transformation of HhaI Methyltransferase: An Induced-Fit Base-Flipping Hypothesis
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期刊论文 |
Zheng, Mingyue|Jiang, Ren-Wang|Jiang, Hualiang|Luo, Cheng| |
| 42 |
Identifying Novel Selective Non-Nucleoside DNA Methyltransferase 1 Inhibitors through Docking-Based Virtual Screening
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期刊论文 |
Jiang, Hualiang|Liu, Bo|Zheng, Mingyue|Luo, Cheng| |
| 43 |
Rapid and selective access to three distinct sets of indole-based heterocycles from a single set of Ugi-adducts under microwave heating
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期刊论文 |
Fei Zhao|Mingyue Zheng|Yun Zhai|Hong Liu| |
| 44 |
Asymmetric synthesis of alpha-(1-oxoisoindolin-3-yl)glycine: synthetic and mechanistic challenges
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期刊论文 |
Wang, Jiang|Luis Acena, Jose|Soloshonok, Vadim A.|Liu, Hong| |
| 45 |
Chemical Kinetic Resolution of Unprotected β-Substituted-β-Amino Acids Using Recyclable Chiral Ligands
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期刊论文 |
Xia Chen|José Luis Ace？a|Vadim A. Soloshonok|Hong Liu| |
| 46 |
Three-Step One-Pot Synthesis of 1,4-Dihydropyrazolo[ 4,3-b] indoles Using Copper Catalysis
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期刊论文 |
Liu, Hailong|Zhang, Lei|Zhao, Fei|Liu, Hong| |
| 47 |
Microwave-assisted synthesis of 5,6-dihydroindolo[1,2-a]quinoxaline derivatives through copper-catalyzed intramolecular N-arylation
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期刊论文 |
Lei Zhang|Hailong Liu|Shengbing Zhou|Hong Liu| |
| 48 |
Gold(I)-Catalyzed Cascade Approach for the Synthesis of Tryptamine-Based Polycyclic Privileged Scaffolds as alpha(1)-Adrenergic Receptor Antagonists
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期刊论文 |
Zhang, Lei|Wang, Jinfang|Xie, Xin|Liu, Hong| |
| 49 |
One-pot metal-free synthesis of highly substituted pyrroles from 2-acetyl-3-methylene-1,4-dicarbonyl compounds and primary amines via TBHP and activated carbon oxidative aromatization of dihydropyrrole
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期刊论文 |
Sun, Haifeng|Zhang, Lei|Zhao, Fei|Liu, Hong| |
| 50 |
中国药学会科学技术奖
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奖励 |
孟韬|马兰萍|周宇|王江| |
| 51 |
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II-III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
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期刊论文 |
Luis Acena, Jose|Soloshonok, Vadim A.|Izawa, Kunisuke|Liu, Hong| |
| 52 |
Palladium-Catalyzed Difunctionalization of Alkynes via C-N and S-N Cleavages: A Versatile Approach to Highly Functional Indoles
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期刊论文 |
Nian, Yong|Zhang, Lei|Yang, Wei|Liu, Hong| |
| 53 |
上海市药学科技奖
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奖励 |
马兰萍|周宇|李建|王昕| |
| 54 |
Design, synthesis, structure-activity relationships, and docking studies of pyrazole-containing derivatives as a novel series of potent glucagon receptor antagonists
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期刊论文 |
Wang, Jiang|Yang, Dehua|Wang, Ming-Wei|Liu, Hong| |
| 55 |
Design, synthesis and biological evaluation of novel 6-alkenylamides substituted of 4-anilinothieno[2,3-d]pyrimidines as irreversible epidermal growth factor receptor inhibitors
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期刊论文 |
Jiang, Hualiang|Ding, Jian|Xie, Hua|Liu, Hong| |
| 56 |
Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
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期刊论文 |
Li, Jia|Zhao, Linxiang|Jiang, Hualiang|Liu, Hong| |
| 57 |
Highly diastereoselective synthesis of 3-indolylglycines via an asymmetric oxidative heterocoupling reaction of a chiral nickel(II) complex and indoles
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期刊论文 |
Shengbin Zhou|Jie Lian|Hualiang Jiang|Hong Liu| |
| 58 |
Purely Chemical Approach for Preparation of D-alpha-Amino Acids via (S)-to-(R)-Interconversion of Unprotected Tailor-Made alpha-Amino Acids
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期刊论文 |
Moriwaki, Hiroki|Kawashima, Aki|Soloshonok, Vadim A.|Liu, Hong| |
| 59 |
Asymmetric Synthesis of Chiral Heterocyclic Amino Acids via the Alkylation of the Ni(II)-complex of Glycine and Alkyl Halides
|
期刊论文 |
Hui Chen|Jiang Wang|Shengbin Zhou|Hong Liu| |
| 60 |
Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets
|
期刊论文 |
Huang, Ming|Geng, Meiyu|Spiegel, Sarah|Luo, Cheng| |
| 61 |
Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbonitrile derivatives as dipeptidyl peptidase IV inhibitors
|
期刊论文 |
Li, Jia|Zhao, Linxiang|Jiang, Hualiang|Liu, Hong| |
