低聚原花青素Cinnamtannin D1通过促进自噬保护胰岛β细胞的药理机制研究

81773791
2017
H3507.代谢性疾病药物药理
王贺瑶
面上项目
研究员
中国科学院上海药物研究所
48万元
2型糖尿病;自噬;凋亡;低聚原花青素;β细胞
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Benzbromarone aggravates hepatic steatosis in obese individuals 期刊论文 Sun Peng;Zhu Jing-Jie;Wang Ting;Huang Qi;Zhou Yu-Ren;Yu Bang-Wei;Jiang Hua-Liang;Wang He-Yao
2 中药桂枝化学成分研究 期刊论文 王丹;吴喜民;张东东;朱博荣;王顺春;王晨星;贾琦;李医明
3 一种具有降糖降脂作用的组合物及其应用 专利 贾琦;李医明;王贺瑶;陈凯先;张皓月;王雪萍;朱博荣;王丹
4 A novel low systemic diacylglycerol acyltransferase 1 inhibitor, Yhhu2407, improves lipid metabolism 期刊论文 Jun-Shang Huang;Bin-Bin Guo;Fei-Fei Lin;Li-Min Zeng;Ting Wang;Xiang-Yu Dang;Yang Yang;You-Hong Hu;Jia Liu;He-Yao Wang
5 Procyanidin C1, a Component of Cinnamon Extracts, Is a Potential Insulin Sensitizer That Targets Adipocytes 期刊论文 Sun Peng;Li Kai;Wang Ting;Ji Jun;Wang Yan;Chen Kai-Xian;Jia Qi;Li Yi-Ming;Wang He-Yao
6 A novel GPR120-selective agonist promotes insulin secretion and improves chronic inflammation 期刊论文 Liu Yang;Xian-Tao Lei;Qi Huang;Ting Wang;Hong-Bin Sun;He-Yao Wang
7 Exogenous FABP4 interferes with differentiation, promotes lipolysis and inflammation in adipocytes 期刊论文 Dou Hui-Xia;Wang Ting;Su Hai-Xia;Gao Ding-Ding;Xu Ye-Chun;Li Ying-Xia;Wang He-Yao
8 Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor 期刊论文 He Yulong;Dou Huixia;Gao Dingding;Wang Ting;Zhang Mingming;Wang Heyao;Li Yingxia
9 Combined treatment with FABP4 inhibitor ameliorates rosiglitazone-induced liver steatosis in obese diabetic db/db mice 期刊论文 Meng-Ting Chen;Jun-Shang Huang;Ding-Ding Gao;Ying-Xia Li;He-Yao Wang
10 桂枝中羧酸及其衍生物的化学成分研究 期刊论文 王丹;吴喜民;张东东;朱博荣;贾琦;李医明
11 DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis 期刊论文 Huang Jun-shang;Guo Bin-bin;Wang Gai-hong;Zeng Li-min;Hu You-hong;Wang Ting;Wang He-yao
12 Neuroprotective Effects of B-Type Cinnamon Procyanidin Oligomers on MPP+-Induced Apoptosis in a Cell Culture Model of Parkinson’s Disease 期刊论文 Qi Xu;Zi-Yu Chen;Bo-Rong Zhu;Yi-Ming Li;Manju B. Reddy;Hui-Lin Liu;Guo-Dong Dang;Qi Jia;Xiao-Jun Wu
13 交泰丸中小檗碱联合cinnamtannin D1的降血糖作用 期刊论文 王雪萍;张皓月;王婷;李医明;陈凯先;王贺瑶;贾琦
14 Cinnamtannin D1 Protects Pancreatic β‑Cells from Glucolipotoxicity- Induced Apoptosis by Enhancement of Autophagy In Vitro and In Vivo 期刊论文 Xin-Yi Wang;Bo-Rong Zhu;Qi Jia;Yi-Ming Li;Ting Wang;He-Yao Wang
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