表观遗传调控的海马突触结构可塑性的改变在大鼠海洛因渴求和复吸中的作用及其机制研究
81671322
2016
H1004.物质依赖和其他成瘾性障碍
刘景根
面上项目
研究员
中国科学院上海药物研究所
62万元
表观遗传;海马;海洛因成瘾;突触可塑性;DNA甲基化
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Anteromedial thalamic nucleus to anterior cingulate cortex inputs modulate histaminergic itch sensation | 期刊论文 | Deng Ying-Zhi;Lu Yu-Chen;Wu Wei-Wei;Cheng Li;Zan Gui-Ying;Chai Jing-Rui;Wang Yu-Jun;Chen Zhong;Liu Jing-Gen |
| 2 | Ube2b-dependent degradation of DNMT3a relieves a transcriptional brake on opiate-induced synaptic and behavioral plasticity | 期刊论文 | Zhong-Guo Chen;Yu-Jun Wang;Ruo-Song Chen;Fan Geng;Chen-Ling Gan;Wei-Sheng Wang;Xing Liu;Hu Zhou;Ling He;Gang Hu;Jing-Gen Liu |
| 3 | ACC to Dorsal Medial Striatum Inputs Modulate Histaminergic Itch Sensation. | 期刊论文 | Lu Yu Chen;Wang Yu Jun;Lu Bin;Chen Ming;Zheng Ping;Liu Jing Gen |
| 4 | Proteomic analysis of male rat nucleus accumbens, dorsal hippocampus and amygdala on conditioned place aversion induced by morphine withdrawal | 期刊论文 | Guo Liu bin;Yu Chuan;Ling Qing lan;Fu Yu;Wang Yu jun;Liu Jing gen |
| 5 | Src-dependent phosphorylation of mu-opioid receptor at Tyr(336) modulates opiate withdrawal | 期刊论文 | Zhang Lei;Kibaly Cherkaouia;Wang Yu Jun;Xu Chi;Song Kyu Young;McGarrah Patrick W;Loh Horace H;Liu Jing Gen;Law Ping Yee |
| 6 | Discovery of a Highly Selective and Potent kappa Opioid Receptor Agonist from N-Cyclopropylmethyl-7 alpha-phenyl-6,14-endoethanotetrahydronorthebaines with Reduced Central Nervous System (CNS) Side Effects Navigated by the Message-Address Concept | 期刊论文 | Xiao Li;Wang Yujun;Zhang Mumei;Wu Weiwei;Kong Linghui;Ma Yan;Xu Xuejun;Liu Xiao;He Qian;Qian Yuanyuan;Sun Huijiao;Wu Haihao;Lin Cheng;Huang Huoming;Ye Rongrong;Jiang Shuang;Ye Ru-Feng;Yuan Congmin;Fang Shengyang;Xue Dengqi;Yang Xicheng;Chen Hao;Zheng Yilin;Yu Linqian;Xie Qiong;Zheng Lan;Fu Wei;Li Wei;Qiu Zhuibai;Liu Jinggen;Shao Liming |
| 7 | 7 beta-Methyl substituent is a structural locus associated with activity cliff for nepenthone analogues | 期刊论文 | Sun Hui jiao;Wang Yu hua;Yuan Cong min;Kong Ling hui;Xu Xue jun;Wang Yu jun;Wu Hai hao;Lin Cheng;Qian Yuan yuan;Huang Huo ming;Xiao Li;Liu Xiao;He Qian;Fang Sheng yang;Xue Deng qi;Yang Xi cheng;Chen Hao;Zheng Yi lin;Zheng Lan;Yu Lin qian;Xie Qiong;Fu Wei;Li Wei;Liu Jing gen;Qiu Zhui bai;Shao Li ming |
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