AMPK参与DNA损伤修复的蛋白调控网络及其分子机制研究

31871414
2018
C0702.细胞信号转导
臧奕
面上项目
研究员
中国科学院上海药物研究所
59万元
DNA损伤修复;磷酸化;信号网络;单磷酸腺苷激活的蛋白激酶
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Phosphoproteomics Reveals AMPK Substrate Network in Response to DNA Damage and Histone Acetylation 期刊论文 Yuejing Jiang;Xiaoji Cong;Shangwen Jiang;Ying Dong;Lei Zhao;Yi Zang;Minjia Tan;Jia Li
2 Microenvironment-Responsive Small-Molecule Probe for Pulmonary Fibrosis Detection 期刊论文 Ying Dong;Xiao-Rong Li;Qi Chen;Rui-Ying GUO;Bi-Xi Tang;Wei-Juan Kan;Wei Zhang;Yongzhou Hu;Jia Li;Yi Zang;Xin Li
3 AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ. 期刊论文 Jiang Yuejing;Dong Ying;Luo Yifeng;Jiang Shangwen;Meng Fei-Long;Tan Minjia;Li Jia;Zang Yi
4 Roxithromycin attenuates bleomycin-induced pulmonary fibrosis by targeting senescent cells 期刊论文 Xuan Zhang;Ying Dong;Wan-chen Li;Bi-xi Tang;Jia Li;Yi Zang
5 A fluorogenic probe for tracking GSH flux in developing neurons 期刊论文 Haichao Zong;Jiayi Peng;Xiao-Rong Li;Meng Liu;Yongzhou Hu;Jia Li;Yi Zang;Xin Li;Tony D.James
6 Discovery of a 2-pyridinyl urea-containing compound YD57 as a potent inhibitor of apoptosis signal-regulating kinase 1 (ASK1) 期刊论文 Zhang Shiyan;Huang Chaoying;Lyu Xilin;Wang Peipei;Zang Yi;Wang Zengtao;Wang Huan;Li Jia;Zhao Yujun
7 Sleeve gastrectomy ameliorated high-fat diet (HFD)-induced non-alcoholic fatty liver disease and upregulated the nicotinamide adenine dinucleotide+/ Sirtuin-1 pathway in mice 期刊论文 Rong Hua;Guan-Zhen Wang;Qi-Wei Shen;Ye-Ping Yang;Meng Wang;Meng Wu;Yi-Kai Shao;Min He;Yi Zang;Qi-Yuan Yao;Zhao-Yun Zhang
8 Selective and sensitive fluorescence imaging reveals microenvironment-dependent behavior of NO modulators in the endothelial system 期刊论文 Dong Ying;Li Xiaorong;Li Jia;Zang Yi;Li Xin
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