蛋白聚糖glypican-1和syndecan-1糖链的降解与肿瘤生长,侵袭和转移关系的机制及其应用研究

30670470
2006
C0506.糖、脂生物化学
丁侃
面上项目
研究员
中国科学院上海药物研究所
32万元
Heparanase;syndecan-1;NOS;NDST-3;glypican-1
2007-01-01到2009-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Anti-cancer drug development from Chinese herbal medicine 会议论文 丁侃|
2 Structure and chain conformation of a (1 &rarr 6)-α-d-glucan from the root of Pueraria lobata (Willd.) Ohwi and the antioxidant activity of its sulfated derivative 期刊论文 Ding, Kan|Zhang, Hongfeng|Zhang, Lina|Tao, Yongzhen|Liu, Qin|Cui, Hengxiang|
3 MicroRNAs regulate Heparan sulfate proteoglycan’s function 会议论文 丁侃|
4 Heparan sulfate degradation is required for tumor survival and invasion? 会议论文 丁侃|
5 Structural characterization and immunological activity of two cold-water extractable polysaccharides from Cistanche deserticola Y. C. Ma 期刊论文 Ding, Kan|Yao, Jian|Fang, Ji-nian|Dong, Qun|
6 Waltonitone induces human hepatocellular carcinoma cells apoptosis in vitro and in vivo. 期刊论文 Shuo Wang|Kan Ding|Zhang Zhang|Zhengtao Wang|Hong Qiu|Chaohui Duan|
7 New oligosaccharides prepared by acid hydrolysis of the polysaccharides from Nerium indicum Mill and their anti-angiogenesis activities 期刊论文 Wang, Shunchun|Liu, Qin|Ding, Kan|Hu, Ke|
8 Bioactivity and mechanism study of glycans from Chinese herbal medicine. 会议论文 丁侃|
9 A novel Id1 expression inhibitor, sulfated polysaccharide represses hepatocarcinoma growth via disrupting angiogenesis 会议论文 丁侃|
10 A Polysaccharides, MDG-1, induces S1P1 and bFGF expression and augments survival and angiogenesis in the ischemic heart. 期刊论文 Kan Ding|De-Sheng Xu|Zhang Zhang|Yi Feng|Xiao Lin|Shuo Wang|
11 Sulfated polysaccharide KD1 inhibits angiogenesis via down-regulating Id1 expression. 会议论文 丁侃|
12 Target angiogenesis for glycan-based drug discovery. 会议论文 丁侃|
13 Reciprocal regulation between microRNAs and heparan sulfate proteoglycan involved in cell growth and angiogenesis. 会议论文 丁侃|
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