酶催化合成多糖作为多功能药物载体的研究

21372238
2013
B0702.生物分子的化学生物学
黄蔚
面上项目
研究员
中国科学院上海药物研究所
80万元
药物载体;酶催化合成;多糖
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Real-Time Analysis on Drug-Antibody Ratio of Antibody-Drug Conjugates for Synthesis, Process Optimization, and Quality Control 期刊论文 Tang Yubo;Tang Feng;Yang Yang;Zhao Lei;Zhou Hu;Dong Jinhua;Huang Wei
2 Regioselective protection of xylose for efficient synthesis of arabino-alpha-1,3-xylosides 期刊论文 Cai Deqin;Guan Dongliang;Ding Kan;Huang Wei
3 Glycoengineering and glycosite-specific labeling of serum IgGs from various species 期刊论文 Guo Weilai;Tang Feng;Qin Ken;Zhou Mang;Le Zhiping;Huang Wei
4 Aspartic Acid Side-Chain Benzyl Ester as a Multifunctionalization Precursor for Synthesis of Branched and Cyclic Arginylglycylaspartic Acid Peptides 期刊论文 Tian Xiaobo;Yu Pengqiu;Tang Yubo;Le Zhiping;Huang Wei
5 A new strategy for synthesis of branched cyclic peptide by Asn side-chain hydrazide ligation 期刊论文 Lu Jian;Tian Xiao-Bo;Huang Wei
6 Biochemical features of theadhesion G protein-coupled receptor CD97 for its functions of auto-proteolysisand HeLa cell attachment. 期刊论文 Li-yun Yang;Xiao-fang Liu;Yang Yang;Lin-lin Yang;Kai-wen Liu;Yu-bo Tang;Min Zhang;Min-jia Tan;Shan-mei Cheng;Ye-chun Xu;Huai-yu Yang;Zhi-jie Liu;Gao-jie Song;Wei Huang
7 匹杉琼作为淋巴示踪剂的应用 专利 黄蔚;王洪;田小波;蒋柏凤
8 One-pot N-glycosylation remodeling of IgG with non-natural sialylglycopeptides enables glycosite-specific and dual-payload antibody-drug conjugates 期刊论文 Tang Feng;Yang Yang;Tang Yubo;Tang Shuai;Yang Liyun;Sun Bingyang;Jiang Bofeng;Dong Jinhua;Liu Hong;Huang Min;Geng Mei-Yu;Huang Wei
9 Optimal peptide hydrazide ligation with C-terminus Asp, Asn, and Gln hydrazides 期刊论文 Tian Xiaobo;Li Jie;Huang Wei
10 N-glycosylation of the beta(2) adrenergic receptor regulates receptor function by modulating dimerization 期刊论文 Li Xiaona;Zhou Mang;Huang Wei;Yang Huaiyu
11 超声条件下选择性脱除Fmoc-Asn(Ac_3GlcNAc)-OH的O-乙酰基 期刊论文 孙冰洋;田小波;黄蔚;董金华
12 一类寡糖连接子以及利用该寡糖连接子制备的定点连接的抗体-药物偶联物 专利 黄蔚;耿美玉;黄敏;唐峰;唐宇博;杨洋;唐帅
13 一类万古霉素衍生物、其制备方法、药物组合物和用途 专利 黄蔚;蓝乐夫;熊伦;管栋梁;陈菲菲;杨丽韵
14 A simplified procedure for gram-scale production of sialylglycopeptide (SGP) from egg yolks and subsequent semi-synthesis of Man3GlcNAc oxazoline. 期刊论文 Sun Bingyang;Bao Wenzheng;Tian Xiaobo;Li Mingjing;Liu Hong;Dong Jinhua;Huang Wei
15 Extra sugar on vancomycin: new analogues for combating multidrug-resistant Staphylococcus aureus and vancomycin-resistant Enterococci. 期刊论文 Guan D.;Chen F.;Xiong L.;Tang F.;Faridoon;Qiu Y.;Zhang N.;Gong L.;Li J.;Lan L.;Huang W.
16 特拉万星合成工艺研究 期刊论文 熊伦;管栋梁;李剑;黄蔚
17 Chemoenzymatic synthesis of glycoengineered IgG antibodies and glycosite-specific antibody-drug conjugates 期刊论文 Tang Feng;Wang Lai-Xi;Huang Wei
18 Glycoconjugate probes containing a core-fucosylated N-glycan trisaccharide for fucose lectin identification and purification 期刊论文 Cai Deqin;Xun Chaochao;Tang Feng;Tian Xiaobo;Yang Liyun;Ding Kan;Li Wenzhe;Le Zhiping;Huang Wei
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