纳米材料包被的供体T细胞通过免疫隔离缓解移植物抗宿主疾病并保留移植物抗白血病研究

U1803129
2018
H3504.抗炎与免疫药物药理
张玲玲
联合基金项目
教授
安徽医科大学
56万元
纳米包被;T细胞;移植物抗宿主疾病;免疫隔离;移植物抗淋巴瘤
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 酪氨酸激酶抑制剂治疗类风湿关节炎研究进展 期刊论文 疏金玲;张玲玲;魏伟
2 细胞焦亡机制及与疾病的关系 期刊论文 梅旦;张玲玲;魏伟
3 我国学者积极开展COVID -19防治研究并取得重要成果 期刊论文 徐莉;葛瑾茹;张玲玲;魏伟
4 Janus激酶- 信号转导与转录激活子信号通路参与银屑病的研究现状 期刊论文 葛瑾茹;张玲玲;魏伟
5 Advances in the treatment of graft-versus-host disease with immunomodulatory cells 期刊论文 Qianqian Yu;Han Wang;Lingling Zhang;Wei Wei
6 IgD promotes the activation of WNT-Frizzled-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of hIgDFc-Ig fusion protein 会议论文 Yue Zhu;Xiaoyu Cai;Li Xu;Jinru Ge;Faqin Liang;Dan Mei;Xianzheng Zhang;Lingling Zhang;Wei Wei
7 TLR4/ NLRP3/ GSDMD signaling pathway mediates pyroptosis of macrophages to involved in synovitis of AA rats and the role of CP-25 会议论文 Li Xu;Lingling Zhang;Wei Wei
8 Anti-inflammatory and immunoregulatory effects of paeoniflorin and total glucosides of paeony 期刊论文 Lingling Zhang;Wei Wei
9 CP-25 alleviate rats collagen induced arthritis by regulating T cell subsets 会议论文 Lingling Zhang;Wei Wei
10 MicroRNA-124 inhibits hepatic stellate cells inflammatory cytokines secretion by targeting IQGAP1 through NF-κB pathway 期刊论文 Junfa Yang;Changqing Xu;Maomao Wu;Ying Wu;Xiaodi Jia;Chang Zhou;Xianzheng Zhang;Shenling Ge;Li Zeng;Lingling Zhang
11 The Therapeutic Effect of hIgD-Fc-Ig on Adjuvant Arthritis Rats and the Regulation of TCR-Lck-Erk Pathway in T cells 会议论文 Dan Mei;Lingling Zhang;Wei Wei
12 hIgDFc-Ig inhibits B cell function by regulating the BCR-Syk-Btk-NF-κB signalling pathway in mice with collagen-induced arthritis. 期刊论文 Xianzheng Zhang;Dan Mei;Han Wang;Qianqian Yu;Zhongyang Hong;Li Xu;Jinru Ge;Le Han;Jinling Shu;Faqin Liang;Xiaoyu Cai;Yue Zhu;Feng Zhang;Hua Wang;Yu Tai;Qingtong Wang;Lingling Zhang;Wei Wei
13 Cthrc1-mediated multiple signaling in tumor progression and metastasis. 期刊论文 Dan Mei;Yue Zhu;Lingling Zhang;Wei Wei
14 Paeoniflorin-6’-o-benzene sulfonate (CP-25) improves vasculitis through inhibiting IL-17A/JAK/STAT3 signaling pathway in endothelial cells of HFD CIA rats. 期刊论文 Xiao-Yu Cai;Jing-Ru Ge;Li Xu;Fa-Qin Liang;Yue Zhu;Yu Tai;Xian-Zheng Zhang;Jin-Ling Shu;Dan Mei;Le Han;Chen Wang;Xiao-Yu Tang;Ling-Ling Zhang;Wei Wei
15 芍药苷- 6'-O-苯磺酸酯通过调节 JAK/STAT3/ RORγ-t/IL-17A 信号通路抑制人外周血 Th17 细胞的分化. 期刊论文 朱 悦;汤小雨;蔡小雨;王琛;张贤政;韩乐;张玲玲;魏伟
16 IgDFc-Ig, a new biological agent, inhibit the activation of B cells by regulating BCR signaling pathway to treat CIA mice 会议论文 Xianzheng Zhang;Lingling Zhang;Wei Wei
17 Advance of immune cells with negative regulation in treatment for graft-versus-host disease 会议论文 Qianqian Yu;Lingling Zhang;Wei Wei
18 The mechanism of BAFF promoting the inflammatory phonetype of fibroblast-like synovial cells in rheumatoid arthritis and the regulation of MDP 会议论文 Han Wang;Lingling Zhang;Wei Wei
19 Etanercept Inhibits B Cell Differentiation by Regulating TNFRII/ TRAF2/ NF-κB Signaling Pathway in Rheumatoid Arthritis 期刊论文 Xiao-Yu Cai;Yue Zhu;Chen Wang;Xiao-Yu Tang;Le Han;Jin-Ling Shu;Xian-Zheng Zhang;Fa-Qin Liang;Jing-Ru Ge;Li Xu;Dan Mei;Ling-Ling Zhang;Wei Wei
20 银屑病关节炎治疗进展 期刊论文 邰宇;张子璇;张玲玲
21 Influence Factors and Treatment of Psychiatric Disorders in Patients with Rheumatoid Arthritis 会议论文 Han Wang;Lingling Zhang;Wei Wei
22 The monomer derivative of paeoniflorin inhibits macrophage pyroptosis via regulating TLR4/NLRP3/GSDMD signaling pathway in adjuvant arthritis rats 期刊论文 Li Xu;Han Wang;Qianqian Yu;Jinru Ge;Xianzheng Zhang;Dan Mei;Faqin Liang;Xiaoyu Cai;Yue Zhu;Jinling Shu;Yu Tai;Wei Wei;Lingling Zhang
23 BAFF, involved in B cell activation through the NF-κB pathway, is related to disease activity and bone destruction in rheumatoid arthritis. 期刊论文 Ling-Ling Zhang;Hui Xiao;Feng Zhang;Yu-Jing Wu;Jin-Ling Shu;Ying Li;Yu Tai;Sheng-Qian Xu;Jian-Hua Xu;Wei Wei
24 最美科技工作者 奖励 张玲玲
25 hIgD-Fc-Ig regulates T cell function in AA rats by indirectly inhibiting the TCR signaling pathway 会议论文 Jinru Ge;Lingling Zhang;Wei Wei
26 MicroRNA-708 represses hepatic stellate cells activation and proliferation by targeting ZEB1 through Wnt/β-catenin pathway 期刊论文 Junfa Yang;Qing Tao;Yiwen Zhou;Qingfeng Chen;Liangyun Li;Shuang Hu;Yumin Liu;Yu Zhang;Jinling Shu;Xianzheng Zhang;Lei Zhang;Lingling Zhang
27 Src Family Protein Kinase Controls the Fate of B Cells in Autoimmune Diseases 期刊论文 Xianzheng Zhang;Dan Mei;Lingling Zhang;Wei Wei
28 IgD-Fc-Ig fusion protein, a new biological agent, inhibits T cell function in CIA rats by inhibiting IgD-IgDR-Lck-NF-κB signaling pathways. 期刊论文 Le Han;Xianzheng Zhang;Chen Wang;Xiaoyu Tang;Yue Zhu;Xiaoyu Cai;Yujing Wu;Jinling Shu;Qingtong Wang;Jingyu Chen;Yan Chang;Huaxun Wu;Lingling Zhang;Wei Wei
29 IL-17A/JAKs/STAT3 signaling pathway is involved in vasculitis of CIA rats by activating endothelial cells and the role of CP-25 会议论文 Xiaoyu Cai;Yue Zhu;Jinru Ge;Li Xu;Dan Mei;Jinling Shu;Xianzheng Zhang;Lingling Zhang;Wei Wei
30 IgD promotes pannus formation by activating Wnt5A-Fzd5-CTHRC1-NF-κB signaling pathway in FLS of CIA rats and the regulation of IgD-Fc-Ig fusion protein 期刊论文 Yu Tai;Yue Zhu;Dan Mei;Han Wang;Qianqian Yu;Chongyang Hong;Xiaoyu Cai;Li Xu;Jinru Ge;Faqin Liang;Chunru Jiang;Ziyang Xue;Ling Hu;Ruijin Liu;Tianjing Zhang;Pan Wang;Xianzheng Zhang;Feng Zhang;Lingling Zhang
31 TLR4/ NLRP3/ GSDMD signaling pathway mediate macrophage pyroptosis of adjuvant arthritis rats and the role of MDP 会议论文 Qianqian Yu;Lingling Zhang;Wei Wei
32 进行性肌营养不良动物模型及治疗药物研究进展 期刊论文 张贤政;葛瑾茹;张玲玲;魏伟
33 CP-25 alleviated collagen induced arthritis mice through BAFF-NFκB signaling by influencing the activity of TRAF2 会议论文 Jinling Shu;Lingling Zhang;Wei Wei
34 炎症小体参与自身免疫性疾病的研究进展 期刊论文 徐莉;张玲玲;魏伟
35 BAFF promotes the activation of fibroblast-like synoviocyte through the BAFF-BAFFR-TRAF2/3 signaling pathway 会议论文 Faqin Liang;Lingling Zhang;Wei Wei
36 The advances in pyroptosis initiated by inflammasome in inflammatory and immune diseases 期刊论文 Faqin Liang;Feng Zhang;Lingling Zhang;Wei Wei
37 内皮细胞活化参与类风湿血管炎病理机制研究进展 期刊论文 朱悦;张玲玲;魏伟
38 细胞焦亡机制及与疾病关系的研究进展 会议论文 梅旦;张玲玲;魏伟
39 Anti-inflammatory and immunomodulatory drug CP-25 alleviates experimental arthritis in mice by inhibiting B cells functions through regulating BAFF signaling and comparative efficacy with biological agents 会议论文 Lingling Zhang;Wei Wei
40 一种GA-T细胞及其制备方法以及在白血病和抗GVHD中的应用 专利 张玲玲;梅旦;薛子扬;张贤政;于倩倩
41 JAK-STAT信号通路参与银屑病的研究进展 会议论文 葛瑾茹;张玲玲;魏伟
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