C60-RAPA纳米微球上调自噬和突触CaMKII在改善七氟烷诱导POCD中的作用机制研究
81870841
2018
H0902.意识障碍与认知功能障碍
刘学胜
面上项目
教授
安徽医科大学
56万元
术后认知功能障碍;七氟烷;自噬;纳米-富勒烯;β-淀粉样蛋白
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 微创麻醉技术加速病人术后快速康复的临床应用 | 奖励 | 刘学胜;陆姚;程新琦;杨志来;王纯辉;徐光红;张继千;沈启英 |
| 2 | Contribution of intraoperative electroencephalogram suppression to frailty-associated postoperative delirium: mediation analysis of a prospective surgical cohort | 期刊论文 | Panpan Fang;Zixiang Shang;Jian Xu;Jun Hu;Sichen Zhang;Yinguang Fan;Yao Lu;Xuesheng Liu;Mervyn Maze |
| 3 | The influence of anesthesia and surgery on fear extinction | 期刊论文 | Xin Qing;Yuan-ling Xu;Hu Liu;Xue-sheng Liu |
| 4 | Autophagy impairment is involved in midazolam-induced lipid droplet accumulation and consequent phagocytosis decrease in BV2 cells | 期刊论文 | Xiaoling Zhu;Huiwen Zhang;Wenjing Peng;Shan Gao;Zhilai Yang;Jiqian Zhang;Xuesheng Liu |
| 5 | Effect of Intraoperative Dexmedetomidine on Recovery of Gastrointestinal Function After Abdominal Surgery in Older Adults | 期刊论文 | Yao Lu;Pan-Pan Fang;Yong-Qi Yu;Xin-Qi Cheng;Xiao-Mei Feng;Gordon Tin Chun Wong;Mervyn Maze;Xue-Sheng Liu;Yong-Quan Chen;Xian-Wen Hu;Chun-Hui Wang;Xin Wei;Hao Yuan;Xiao-Qiong Xia;Sheng-Bin Wang;Qi Zhang;Jin-Bao Chen;Rui Zhan;Hui Xu;Qing Zhang;Yinguang Fan |
| 6 | Graphene oxide improves postoperative cognitive dysfunction by maximally alleviating amyloid beta burden in mice | 期刊论文 | Jiqian Zhang;Shasha Zhu;Peipei Jin;Yuting Huang;Qingqing Dai;Qianyun Zhu;Pengfei Wei;Zhilai Yang;Lei Zhang;Hu Liu;Guanghong Xu;Lijian Chen;Erwei Gu;Yunjiao Zhang;Longping Wen;Xuesheng Liu |
| 7 | Nano C60 Promotes Synaptic Distribution of Phosphorylated CaMKIIα and Improves Cognitive Function in APP/PS1 Transgenic Mice | 期刊论文 | Wei Dai;Mingxu Zhao;Caiyun Chen;Chang Zhou;Peng Wang;Zhilai Yang;Shan Gao;Yao Lu;Jiqian Zhang;Xuesheng Liu |
| 8 | Preoperative Status of Gut Microbiota Predicts Postoperative Delirium in Patients With Gastric Cancer | 期刊论文 | Hu Liu;Gao Cheng;Yuan-ling Xu;Qi Fang;Lei Ye;Chun-hui Wang;Xue-sheng Liu |
| 9 | TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced beta-Amyloid Accumulation | 期刊论文 | Cheng Dan;Tan Qilian;Zhu Qianyun;Zhang Jiqian;Han Xiaoyu;Fang Panpan;Jin Weilin;Liu Xuesheng |
| 10 | 术后认知功能障碍的分子机制研究及临床防治策略 | 奖励 | 刘学胜;徐光红;沈启英;程新琦;张雷;杨志来 |
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