GRK2/Epac1调控肝星状细胞表型转化在肝纤维化形成中的作用及机制

81770605
2017
H0310.肝损伤、修复与再生
孙妩弋
面上项目
教授
安徽医科大学
56万元
肝纤维化;肝星状细胞;Epac1;GRK2
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Inflammasome as an Effective Platform for Fibrosis Therapy. 期刊论文 Chen Ting-Ting;Xiao Feng;Li Nan;Shan Shan;Qi Meng;Wang Zi-Ying;Zhang Sheng-Nan;Wei Wei;Sun Wu-Yi
2 G蛋白偶联受体与肝损伤的研究现状 期刊论文 孙家昌;孙妩弋;厉歆然;彭文婷;魏伟
3 Epac信号分子在纤维化疾病中作用的研究进展 期刊论文 杜佳佳;孙妩弋;彭文婷;孙家昌;魏伟
4 炎症小体在纤维化疾病中作用的研究进展 期刊论文 李南;孙妩弋;孙家昌;杜佳佳;李秀芹;魏伟
5 Depletion of beta-arrestin 2 protects against CCl4-induced liver injury in mice. 期刊论文 Sun Jia-Chang;Du Jia-Jia;Li Xiu-Qin;Li Nan;Wei Wei;Sun Wu-Yi
6 Arrb2基因敲除小鼠的繁育及基因型鉴定 期刊论文 孙妩弋;孙家昌;厉歆然;彭文婷;魏伟
7 β-arrestin2 deficiency protects against hepatic fibrosis in mice and prevents synthesis of extracellular matrix. 期刊论文 Sun Wu-Yi;Gu Yuan-Jing;Li Xin-Ran;Sun Jia-Chang;Du Jia-Jia;Chen Jing-Yu;Ma Yang;Wang Qing-Tong;Wei Wei
8 Role of Epac1 on phenotypic transformation of hepatic stellate cells and the effect of CP-25 会议论文 Du Jia-jia;Sun Jia-chang;Li Nan;Li Xiu-qin;Wei Wei;Sun Wu-yi
9 Emerging Roles of G Protein-Coupled Receptors in Hepatocellular Carcinoma. 期刊论文 Peng Wen-Ting;Sun Wu-Yi;Li Xin-Ran;Sun Jia-Chang;Du Jia-Jia;Wei Wei
10 G protein-coupled receptor kinase 2 regulating beta2-adrenergic receptor signaling in M2-polarized macrophages contributes to hepatocellular carcinoma progression. 期刊论文 Wu Jing-Jing;Yang Yang;Peng Wen-Ting;Sun Jia-Chang;Sun Wu-Yi;Wei Wei
11 G protein-coupled receptor kinase 2 as novel therapeutic target in fibrotic diseases 期刊论文 Nan Li;Shan Shan;Xiu-Qin Li;Ting-Ting Chen;Meng Qi;Sheng-Nan Zhang;Zi-Ying Wang;Ling-Ling Zhang;Wei Wei;Wu-Yi Sun
12 β-arrestin2 regulating β2-adrenergic receptor signaling in hepatic stellate cells contributes to hepatocellular carcinoma progression. 期刊论文 Li Xiu-Qin;Peng Wen-Ting;Shan Shan;Wu Jing-Jing;Li Nan;Du Jia-Jia;Sun Jia-Chang;Chen Ting-Ting;Wei Wei;Sun Wu-Yi
13 β-Arrestin2 deficiency attenuates oxidative stress in mouse hepatic fibrosis through modulation of NOX4. 期刊论文 Du JiaJia;Sun JiaChang;Li Nan;Li XiuQin;Sun WuYi;Wei Wei
14 GRK2 Suppresses Hepatocellular Carcinoma Metastasis and Invasion Through Down-Regulation of Prostaglandin E Receptor 2. 期刊论文 Li Nan;Wu Jing-Jing;Chen Ting-Ting;Li Xiu-Qin;Du Jia-Jia;Shan Shan;Wei Wei;Sun Wu-Yi
15 β-arrestin2 deficiency protects against hepatic fibrosis in mice and prevents synthesis of extracellular matrix 会议论文 Wu-Yi Sun
16 The role of G protein-coupled receptor kinases in the pathology of malignant tumors. 期刊论文 Sun Wu-Yi;Wu Jing-Jing;Peng Wen-Ting;Sun Jia-Chang;Wei Wei
17 不同浓度四氯化碳诱导小鼠肝纤维化模型的比较 期刊论文 孙家昌;孙妩弋;厉歆然;彭文婷;杜佳佳;魏伟
18 人参皂苷CK对人肝癌细胞HepG2迁移及侵袭的影响 期刊论文 彭文婷;孙妩弋;孙家昌;杜佳佳;魏伟
19 G蛋白偶联受体激酶2对纤维化疾病调控作用的研究现状 期刊论文 李秀芹;孙妩弋;李南;杜佳佳;魏伟
20 β2-AR signaling pathway activation contributes to the tumor-promoting effects of hepatic stellate cells in hepatocellular carcinoma 会议论文 Wu-Yi Sun
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