PSTPIP2在肝纤维化形成与逆转中的作用及调控机制研究

81770609
2017
H0310.肝损伤、修复与再生
李俊
面上项目
教授
安徽医科大学
62万元
巨噬细胞;肝纤维化;NOD样受体;PSTPIP2;DNA甲基化
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 4-Methylcoumarin-[5,6-g]-hesperetin attenuates inflammatory responses in alcoholic hepatitis through PPAR-gamma activation 期刊论文 Meng Hong Wu;You Hong Mei;Yang Yang;Zhang Yi Long;Meng Xiao Ming;Ma Tao Tao;Huang Cheng;Li Jun
2 PTP1B promotes macrophage activation by regulating the NF-κB pathway in alcoholic liver injury 期刊论文 Lei Yang;Ying-yin Sun;Ya-ru Liu;Na-na Yin;Fang-tian Bu;Hai-xia Yu;Xiao-sa Du;Jun Li;Cheng Huang
3 PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro 期刊论文 Yao Y;Yu H;Liu Y;Xu Q;Li X;Meng X;Huang C;Li J
4 一种4位,7位双取代的橙皮素衍生物及其制备和作为抗类风湿关节炎的药物中的应用 专利 李俊;张义龙;黄成;马陶陶;李增;孟晓明;孙正浩
5 肝脏疾病的表观遗传修饰调控研究及新靶点发现 奖励 李俊;黄成;孟晓明;吕雄文;徐涛
6 PSTPIP2 connects DNA methylation to macrophage polarization in CCL4-induced mouse model of hepatic fibrosis 期刊论文 Yang Yang;Wu Xiao-qin;Li Wan-xia;Huang Hui-min;Li Hai-di;Pan Xue-yin;Li Xiao-feng;Huang Cheng;Meng Xiao-ming;Zhang Lei;Lv Xiong-wen;Wang Hua;Li Jun
7 Design, Synthesis and Investigation of the Potential Anti-Inflammatory Activity of 7-O-Amide Hesperetin Derivatives 期刊论文 Zhang Yilong;Zheng Yan;Shi Wen;Guo Yahui;Xu Tao;Li Zeng;Huang Cheng;Li Jun
8 PSTPIP2 inhibits cisplatin-induced acute kidney injury by suppressing apoptosis of renal tubular epithelial cells 期刊论文 Zhu H;Jiang WJ;Zhao HZ;He CS;Tang XH;Xu SB;Xu CT;Feng R;Li J;Ma TT;Huang C
9 PSTPIP2在自身炎症性疾病中的研究进展 期刊论文 姚瑶;黄成;李俊
10 Role of the F-BAR Family Member PSTPIP2 in Autoinflammatory Diseases 期刊论文 Xu JJ;Li HD;Du XS;Li JJ;Meng XM;Huang C;Li J
11 一种7-O-酰胺基取代的橙皮素衍生物及其制备方法和应用 专利 李俊;郑燕;张义龙;黄成;马陶陶;孟晓明;石雯
12 一种酰胺基取代的橙皮素衍生物及其制备方法和作为抗阿尔兹海默症的药物中的应用 专利 李俊;张义龙;黄成;李增;马陶陶;孟晓明;李波
13 一种酰胺基取代的橙皮素衍生物及其制备和作为抗炎的药物中的应用 专利 李俊;张义龙;黄成;马陶陶;张磊;黄爱玲
14 PSTPIP2 attenuates joint damage and suppresses inflammation in adjuvant-induced arthritis 期刊论文 Yao Yao;Cai Xiaoyu;Yu Haixia;Xu Qingqing;Li Xiaofeng;Yang Yang;Meng Xiaoming;Huang Cheng;Li Jun
15 DNMT3b-mediated methylation of ZSWIM3 enhances inflammation in alcohol-induced liver injury via regulating TRAF2-mediated NF-kappa B pathway 期刊论文 Li Hai-Di;Chen Xin;Xu Jie-Jie;Du Xiao-Sa;Yang Yang;Li Juan-Juan;Yang Xiao-Juan;Huang Hui-Min;Li Xiao-Feng;Wu Ming-Fei;Zhang Chong;Zhang Chao;Li Zeng;Wang Hua;Meng Xiao-Ming;Huang Cheng;Li Jun
16 The miR-455-3p/HDAC2 axis plays a pivotal role in the progression and reversal of liver fibrosis and is regulated by epigenetics 期刊论文 You HM;Wang L;Bu FT;Meng HW;Pan XY;Li JJ;Zhang YF;Wang A;Yin NN;Huang C;Li J
17 Emerging Roles for NLRC5 in Immune Diseases 期刊论文 Wang JQ;Liu YR;Xia Q;Chen RN;Liang J;Xia QR;Li J
18 LEFTY2 alleviates hepatic stellate cell activation and liver fibrosis by regulating the TGF-β1/Smad3 pathway 期刊论文 Ya-ru Yang;Fang-tian Bu;Yang;Hao Li;Cheng Huang;Xiao-ming Meng;Lei Zhang;Xiong-wen Lv;Jun Li
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