ApoE基因型通过影响肺泡巨噬细胞褪黑素合成调控NLRP3炎症小体活化参与支气管哮喘发病的分子机制

81770032
2017
H0104.支气管哮喘
吴惠梅
面上项目
研究员
安徽医科大学
55万元
褪黑素;NLRP3炎症小体;载脂蛋白E;哮喘;肺泡巨噬细胞
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 新发呼吸道病毒性传染病炎症风暴机制与防治策略研究及其临床应用 奖励 费广鹤;吴惠梅;胡先纬;李永怀;涂友慧;季爽;戴梦缘;韦媛媛
2 Sevoflurane Prevents Airway Remodeling via Downregulation of VEGF and TGF-beta 1 in Mice with OVA-Induced Chronic Airway Inflammation 期刊论文 Shen Qi-Ying;Wu Ling;Wei Chuan-Sheng;Zhou Yan-Nan;Wu Hui-Mei
3 Melatonin enhances autophagy and decreases apoptosis induced by nanosilica in RAW264.7 cells 期刊论文 Zhang Shi-Hai;Wu Hui-Mei;Li Shuai;Wang Mu-Zi;Fang Lei;Liu Rong-Yu
4 CpG oligdeoxynucleotides suppresses endoplasmic reticulum stress via JNK signal in OVA-induced allergic airway inflammation 会议论文 Zhang Hai-Yun;Xie Qiu-Meng;Zhao Cui-Cui;Fei Guang-He;Wu Hui-Mei
5 Estrogen ameliorates allergic airway inflammation by regulating activation of NLRP3 in mice 期刊论文 Cheng Cheng;Wu Hui-Mei;Wang Mu-Zi;Wang Li-Xia;Zou Hong-Yun;Li Shuai;Liu Rong-Yu
6 TLR2-Melatonin Feedback Loop Regulates the Activation of NLRP3 Inflammasome in Murine Allergic Airway Inflammation 期刊论文 Wu Hui-Mei;Zhao Cui-Cui;Xie Qiu-Meng;Xu Juan;Fei Guang-He
7 TLR9 mediates the activation of NLRP3 inflammasome and oxidative stress in murine allergic airway inflammation 期刊论文 Zhao Cui-Cui;Xie Qiu-Meng;Xu Juan;Yan Xue-Bo;Fan Xiao-Yun;Wu Hui-Mei
8 稳定表达人源不同ApoE基因型的Raw264.7细胞系的应用及其制备方法 专利 吴惠梅;谢邱梦;章海云;沙家凤;阮雅
9 ResolvinD1 Protects the Airway Barrier Against Injury Induced by Influenza A Virus Through the Nrf2 Pathway. 期刊论文 Guo Yan;Tu You-Hui;Wu Xu;Ji Shuang;Shen Ji-Long;Wu Hui-Mei;Fei Guang-He
10 Melatonin biosynthesis restored by CpG oligodeoxynucleotides attenuates allergic airway inflammation via regulating NLRP3 inflammasome. 期刊论文 Wu Hui-Mei;Xie Qiu-Meng;Zhao Cui-Cui;Xu Juan;Fan Xiao-Yun;Fei Guang-He
11 Apolipoprotein E negatively regulates murine allergic airway inflammation via suppressing the activation of NLRP3 inflammasome and oxidative stress 期刊论文 Zhao Cui-Cui;Xu Juan;Xie Qiu-Meng;Fan Xiao-Yun;Fei Guang-He;Wu Hui-Mei
12 载脂蛋白E基因多态性通过影响Raw264.7细胞中的褪黑素合成差异调节NLRP3炎症小体的活化 会议论文 吴惠梅;赵翠翠;谢邱梦
13 CpG Oligodeoxynucleotides Attenuate OVA-Induced Allergic Airway Inflammation via Suppressing JNK-Mediated Endoplasmic Reticulum Stress. 期刊论文 Zhang Hai-Yun;Xie Qiu-Meng;Zhao Cui-Cui;Sha Jia-Feng;Ruan Ya;Wu Hui-Mei
14 Dexamethasone alleviate allergic airway inflammation in mice by inhibiting the activation of NLRP3 inflammasome 期刊论文 Guan Ming-Long;Ma Heng-Li;Fan Xiao-Yun;Chen Xu;Miao Man-Li;Wu Hui-Mei
15 Abscisic acid suppresses the activation of NLRP3 inflammasome and oxidative stress in murine allergic airway inflammation. 期刊论文 Zhao Cui-Cui;Xu Juan;Xie Qiu-Meng;Zhang Hai-Yun;Fei Guang-He;Wu Hui-Mei
16 褪黑素在制备抑制新型冠状病毒SARS-CoV-2受体表达药物中的应用 专利 吴惠梅;费广鹤;谢邱梦;赵翠翠;韦媛媛;章海云
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