表征肿瘤微环境中受体膜蛋白动态修饰与相互作用的化学蛋白质组学分析新方法

91953118
2019
B0702.生物分子的化学生物学
田瑞军
重大研究计划
教授
南方科技大学
60万元
生物正交;活体细胞;磷酸化;化学蛋白质组学;蛋白质复合物
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Dynamic phosphotyrosine-dependent signaling profiling in living cells by two-dimensional proximity proteomics 期刊论文 Qian Kong;Mi Ke;Yicheng Weng;Yunqiu Qin;An He;Pengfei Li;Zongwei Cai;Ruijun Tian
2 High-Throughput and Integrated Chemical Proteomic Approach for Profiling Phosphotyrosine Signaling Complexes. 期刊论文 Qian Kong;Peiwu Huang;Bizhu Chu;Mi Ke;Wendong Chen;Zhendong Zheng;Shanping Ji;Zongwei Cai;Pengfei Li;Ruijun Tian
3 Zwitter-ionic Monolith-based Spintip Column Coupled with Evosep One Liquid Chromatography for High-throughput Proteomic Analysis 期刊论文 Yiran Su;Xi Wang;Yun Yang;Lijun Yang;Ruilian Xu;Ruijun Tian
4 一种微流控器件及其应用 专利 田瑞军;陈文东;陆雪
5 微流控器件、微流控装置及自动化蛋白质组学样品前处理平台 专利 田瑞军;陈文东;陆雪
6 Mass spectrometry-based ganglioside profiling provides potential insights into Alzheimer's disease development 期刊论文 Hua Li;Yilian Liu;Zhe Wang;Yuping Xie;Lijun Yang;Yanni Zhao;Ruijun Tian
7 Fully Integrated and Multiplexed Sample Preparation Technology for Sensitive Interactome Profiling 期刊论文 Yiheng Mao;Peizhong Chen;Mi Ke;Xiong Chen;Shanping Ji;Wendong Chen;Ruijun Tian
8 基于SCX/SAX混合填料的集成化蛋白质组学样品前处理平台及其应用 专利 田瑞军;唐君;孙秀杰;陈文东
9 Integrated and high-throughput approach for sensitive analysis of tyrosine phosphoproteome 期刊论文 Qian Kong;Yicheng Weng;Zhendong Zheng;Wendong Chen;Pengfei Li;Zongwei Cai;Ruijun Tian
10 一种多组学分析的样品前处理方法及其应用 专利 田瑞军;高伟娜;张巧云;苏怡然
11 一种全自动化蛋白质组学样品前处理平台及其应用 专利 田瑞军;陆雪;陈文东
12 Spatiotemporal profiling of cytosolic signaling complexes in living cells by selective proximity proteomics 期刊论文 Mi Ke;Xiao Yuan;An He;Peiyuan Yu;Wendong Chen;Yu Shi;Tony Hunter;Peng Zou;Ruijun Tian
13 Multiomic analysis of a dried single-drop plasma sample using an integrated mass spectrometry approach 期刊论文 Weina Gao;Qiaoyun Zhang;Yiran Su;Peiwu Huang;Xue Lu;Qinyue Gong;Wendong Chen;Ruilian Xu;Ruijun Tian
14 Motif-dependent immune co-receptor interactome profiling by photoaffinity chemical proteomics 期刊论文 Xiong Chen;Shanping Ji;Zheyi Liu;Xiao Yuan;Congsheng Xu;Ruxi Qi;An He;Heng Zhao;Haiping Song;Chunlei Xiao;Weina Gao;Peng R. Chen;Ray Luo;Pengfei Li;Fangjun Wang;Xueming Yang;Ruijun Tian
15 Generic plug-and-play strategy for high-throughput analysis of PTM-mediated protein complexes 期刊论文 Yunqiu Qin;Zhendong Zheng;Bizhu Chu;Qian Kong;Mi Ke;Courtney Voss;Shawn S C Li;Ruijun Tian
16 Robust capillary- and micro-flow LC-MS/MS methods for high-throughput proteome profiling 期刊论文 Xintong Sui;Qiong Wu;Xiaozhen Cui;Xi Wang;Luobin Zhang;Nan Deng;Yangyang Bian;Ruilian Xu;Ruijun Tian
17 Spatial proteome profiling by immunohistochemistry-based laser capture microdissection and data-independent acquisition proteomics 期刊论文 Peiwu Huang;Qian Kong;Weina Gao;Bizhu Chu;Hua Li;Yiheng Mao;Zongwei Cai;Ruilian Xu;Ruijun Tian
18 Combinatory data independent acquisition and parallel reaction monitoring method for deep profiling of gangliosides. 期刊论文 Hua Li;Ruilian Xu;Lijun Yang;Hemi Luan;Shili Chen;Lan Chen;Zongwei Cai;Ruijun Tian
19 Spatial proteomics for understanding the tissue microenvironment 期刊论文 Yiheng Mao;Xi Wang;Peiwu Huang;Ruijun Tian
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