以钙离子通道为靶标的新型绿色杀虫剂创制研究

21772103
2017
B0706.药物化学生物学
王宝雷
面上项目
副研究员
南开大学
66万元
双酰胺类杀虫剂;杀虫活性;先导发现与优化;钙离子通道;构效关系
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Anthranilic diamides derivatives as potential ryanodine receptor modulators: Synthesis, biological evaluation and structure activity relationship 期刊论文 Liu Jing-Bo;Li Feng-Yun;Dong Jing-Yue;Li Yu-Xin;Zhang Xiu-Lan;Wang Yuan-Hong;Xiong Li-Xia;Li Zheng-Ming
2 Synthesis and evaluation of novel 1-(((6-substitutedbenzo[d]thiazol-2-yl)amino)(heteroaryl)methyl)naphthalen-2-ol as pesticidal agents 期刊论文 Junfeng Shang;Yuxin Li;Na Yang;Lixia Xiong;Baolei Wang
3 Synthesis and structure-insecticidal activity relationship of novel phenylpyrazole carboxylic acid derivatives containing fluorine moiety 期刊论文 Wang Baolei;Wang Hongxue;Liu Hang;Xiong Lixia;Yang Na;Zhang Yan;Li Zhengming
4 基于邻甲酰氨基苯甲酰胺类RyR杀虫剂的结构改造和生物活性 会议论文 王宝雷;朱洪伟;张吉凤;陈有为;熊丽霞;李正名
5 8-[(3,4,4-三氟丁-3-烯-1-基)硫基]取代的新型甲基黄嘌呤及其衍生物的合成和生物活性 期刊论文 刘航;张舒昀;李欢;张燕;李正名;王宝雷
6 一种含取代磺亚胺酰基芳基的吡唑甲酰胺衍生物及其制备方法和用途 专利 王宝雷;李正名;张燕
7 One-pot synthesis, structure and structure-activity relationship of novel bioactive diphenyl/diethyl (3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl)(arylamino)methylphosp honates 期刊论文 Wang Bao-Lei;Zhu Hong-Wei;Li Zheng-Ming;Zhang Xiao;Yu Shu-Jing;Ma Yi;Song Hai-Bin
8 M-(2-(5-(3-溴-1 -(3-氯吡啶-2-基)-1 H-吡唑-5-基)-1,3,4-噁二唑-2-基)-4-氯-6-甲基苯基)酰胺类新化合物的合成及生物活性 期刊论文 张燕;尚俊峰;李欢;刘航;宋海斌;王宝雷;李正名
9 Synthesis and pesticidal activities of novel anthranilic diamides containing pyridylpyrazole and iminodithiocarbamate or thiosemicarbazone motifs 期刊论文 Qiao-Xia Liu;Bao-Lei Wang;Ming-Zhen Mao;Li-Xia Xiong;Zheng-Ming Li
10 Synthesis, biological evaluation and SAR analysis of novel poly-heterocyclic compounds containing pyridylpyrazole group 期刊论文 Wang Bao-Lei;Zhu Hong-Wei;Li Zheng-Ming;Wang Li-Zhong;Zhang Xiao;Xiong Li-Xia;Song Hai-Bin
11 3-(((3-溴-1-(3-氯吡啶-2-基)-1H-吡唑-5-基)亚甲基)氨基)取代苯并[d][1,2,3]三嗪-4(3H)-酮类化合物的合成及生物活性 期刊论文 张燕;朱洪伟;尚俊峰;王宝雷;李正名
12 Synthesis, Structure and Biological Activities of Novel 2-(Trifluoromethyl)-6-arylimidazo[2,1-b][1,3,4]-thiadiazole (bis-)Mannich Base Derivatives Containing Substitutedpiperazine Moiety 期刊论文 Zhang Yan;Li Zhengming;Song Haibin;Wang Baolei
13 基于酮醇酸还原异构酶的新型含哌嗪的杂环Mannich碱的设计、合成及生物活性研究 会议论文 张燕;王宝雷;李正名
14 Design, Synthesis, Biological Evaluation and SARs of Novel N-Substituted Sulfoximines as Potential Ryanodine Receptor Modulators 期刊论文 Xie Yongtao;Zhou Sha;Li Yuxin;Zhou Shaa;Chen Minggui;Wang Baolei;Xiong Lixia;Yang Na;Li Zhengming
15 含苯并噻唑氨基和杂芳基的萘酚衍生物与制备方法和用途 专利 王宝雷;李正名;尚俊峰
16 Synthesis, insecticidal activities, and SAR studies of novel piperazine-containing heterocyclic mono-/di-/tri-amide derivatives 期刊论文 Huan Li;Hang Liu;Yan Zhang;Na Yang;Lixia Xiong;Zhengming Li;Baolei Wang
17 Design, Synthesis and Biological Evaluation of Novel Thienylpyridyl- and Thioether-Containing Acetamides and Their Derivatives as Pesticidal Agents 期刊论文 Huan Li;Na Yang;Lixia Xiong;Baolei Wang
18 含N-芳基吡咯的邻甲酰氨基苯甲酰胺类化合物与制备方法和应用 专利 李正名;王宝雷;吴长春;熊丽霞;杨娜
19 新型N-取代苯基-2-吡唑基烟酰胺类化合物的合成及其生物活性 期刊论文 尚俊峰;刘巧霞;王宝雷;李正名
20 Synthesis, insecticidal activities and SAR studies of novel anthranilic diamides containing trifluoroethoxyl substituent and chiral amino acid moieties 期刊论文 Zhou Shaa;Zhou Sha;Xie Yongtao;Meng Xiangde;Wang Baolei;Xiong Lixia;Yang Na;Li Zhengming
21 一种含噻吩基吡啶和硫基团的乙酰芳胺衍生物及其制备方法和用途 专利 王宝雷;李欢;杨娜;熊丽霞;李正名
22 新型含取代哌嗪的咖啡因衍生物的合成、结构表征及生物活性研究 期刊论文 张舒昀;刘航;汪蕾;李正名;王宝雷
23 Synthesis and insecticidal evaluation of novel sulfide-containing amide derivatives as potential ryanodine receptor modulators 期刊论文 Yan Zhang;Yuxin Li;Huan Li;Junfeng Shang;Zhengming Li;Baolei Wang
24 Synthesis of novel N-pyridylpyrazole derivatives containing 1,2,4-oxadiazole moiety via 1,3-dipolar cycloaddition and their structures and biological activities 期刊论文 Zhang Yan;Shang Junfeng;Li Huan;Liu Hang;Song Haibin;Wang Baolei;Li Zhengming
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