肝再生磷酸酶-3和法尼基酶双靶点锌配合物抑制剂的设计、合成及抗肿瘤活性研究

21471092
2014
B0702.生物分子的化学生物学
袁彩霞
面上项目
教授
山西大学
85万元
抗肿瘤;锌配合物;法尼基转移酶;肝再生磷酸酶-3;抑制剂
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Ultrashort Beryllium-Beryllium Distances Rivalling Those of Metal-Metal Quintuple Bonds Between Transition Metals 期刊论文 Yuan Caixia;Zhao Xue Feng;Wu Yan Bo;Wang Xiaotai
2 Simulating the effect of a triple bond to achieve the shortest main group metal-metal distance in diberyllium complexes: a computational study 期刊论文 Zhao Xue Feng;Yuan Caixia;Li Si Dian;Wu Yan Bo;Wang Xiaotai
3 丝氨酸N衍生物的金属铜配合物及其制备方法和应用 专利 李艳红;卢丽萍
4 皮考啉腙酸衍生物双氧钒(V)配合物及其制备方法 专利 贾宇琦;卢丽萍;袁彩霞;朱苗力
5 Computational design of organometallic oligomers featuring 1,3-metal-carbon bonding and planar tetracoordinate carbon atoms 期刊论文 Zhao Xue-Feng;Yuan Cai-Xia;Wang Xiang;Li Jia-Jia;Wu Yan-Bo;Wang Xiaotai
6 一种席夫碱铂配合物及其制备方法和应用 专利 袁彩霞;卢丽萍;朱苗力;吴艳波
7 Viable aromatic BenHn stars enclosing a planar hypercoordinate boron or late transition metal 期刊论文 Zhao Xue Feng;Li Jia Jia;Li Hai Ru;Yuan Caixia;Tian Xinxin;Li Si Dian;Wu Yan Bo;Guo Jin Chang;Wang Zhi Xiang
8 一种二维双核锌配位聚合物及其制备方法和应用 专利 李少东;卢丽萍;朱苗力
9 一种席夫碱钯配合物及其制备方法和应用 专利 卢丽萍;高敏;袁彩霞
10 Zigzag double-chain C-Be nanoribbon featuring planar pentacoordinate carbons and ribbon aromaticity 期刊论文 Li Jia Jia;Mu Yuewen;Tian Xinxin;Yuan Caixia;Wu Yan Bo;Wang Qiang;Li Debao;Wang Zhi Xiang;Li Si Dian
11 Synthesis, crystal structure and protein tyrosine phosphatase inhibition of a copper(II) complex with N-(2-pyridylmethyl)-l-serine 期刊论文 Li Yanhong;Yuan Caixia;Lu Liping;Zhu Miaoli;Fu Xueqi;Xing Shu;Gao Zengqiang
12 一种1,2,4-三唑类席夫碱锌配合物及其制备方法和应用 专利 袁彩霞;卢丽萍;朱苗力;吴艳波
13 The degree of pi electron delocalization and the formation of 3D-extensible sandwich structures 期刊论文 Wang Xiang;Wang Qiang;Yuan Caixia;Zhao Xue-Feng;Li Jia-Jia;Li Debao;Wu Yan-Bo;Wang Xiaotai
14 Aspartate aminotransferase is potently inhibited by copper complexes: Exploring copper complex-binding proteome 期刊论文 Jia Yuqi;Lu Liping;Yuan Caixia;Feng Sisi;Zhu Miaoli
15 Synthesis, Crystal Structure and PTPs Inhibition of a Zinc(II) Complex with N-(4-hydroxybenzyl)-L-serine 期刊论文 Li Yan Hong;Lu Li Ping;Zhu Miao Li;Yuan Cai Xia;Feng Si Si;Gao Zeng Qiang
16 一种稀土铈席夫碱配合物及其制备方法和应用 专利 卢丽萍;杜然;袁彩霞
17 N-(2-吡啶甲基)-L-丝氨酸铜配合物的合成、晶体结构及抑制蛋白酪氨酸磷酸酶活性 期刊论文 李艳红;袁彩霞;卢丽萍;朱苗力;付学奇;邢述;高增强
18 A dioxidovanadium (V) complex of NNO-donor Schiff base as a selective inhibitor of protein tyrosine phosphatase 1B: Synthesis, characterization, and biological activities 期刊论文 Jia Yuqi;Lu Liping;Zhu Miaoli;Yuan Caixia;Xing Shu;Fu Xueqi
19 Linear, planar, and tubular molecular structures constructed by double planar tetracoordinate carbon D2hC2(BeH)4species via hydrogen-bridged -BeH2Be-bonds 期刊论文 Zhao Xue-Feng;Li Haixia;Yuan Cai-Xia;Li Yan-Qin;Wu Yan-Bo;Wang Zhi-Xiang
20 Zn(II)-selective and sensitive fluorescent chemosensor based on steric constrains and inhibition of ESIPT 期刊论文 Yuan Caixia;Li Shiyang;Wu Yanbo;Lu Liping;Zhu Miaoli
21 Combining covalent bonding and electrostatic attraction to achieve highly viable species with ultrashort beryllium-beryllium distances: a computational design 期刊论文 Qin Zhen Zhen;Wang Qiang;Yuan Caixia;Yang Yun Tao;Zhao Xue Feng;Li Debao;Liu Ping;Wu Yan Bo
22 三唑席夫碱锌配合物抑制蛋白酪氨酸磷酸酶 1B 活性研究 会议论文 李诗洋;袁彩霞;卢丽萍;朱苗力
23 丝氨酸N衍生物的金属锌配合物及其制备方法和应用 专利 李艳红;卢丽萍;袁彩霞
24 trans-(Aniline-κN)dichlorido(dimethyl sulfoxide-κS)platinum(II) 期刊论文 Wang Weirong;Yuan Caixia
25 Star-like superalkali cations featuring planar pentacoordinate carbon 期刊论文 Guo Jin-Chang;Tian Wen-Juan;Wang Ying-Jin;Zhao Xue-Feng;Wu Yan-Bo;Zhai Hua-Jin;Li Si-Dian
26 A Copper(II) Complex Based on N-(4-hydroxybenzyl)-L-serine: Synthesis, Crystal Structure and Inhibitory Activity on PTP1B and TCPTP 期刊论文 Li Yan Hong;Lu Li Ping;Zhu Miao Li;Yuan Cai Xia;Feng Si Si;Gao Zeng Qiang
27 A triazole Schiff base-based selective and sensitive fluorescent probe for Zn2 +: A combined experimental and theoretical study 期刊论文 Caixia Yuan;Xinyu Liu;Yanbo Wu;Liping Lu;Miaoli Zhu
28 A bifunctional chemosensor for detection of volatile ketone or hexavalent chromate anions in aqueous solution based on a Cd(II) metal-organic framework 期刊论文 Li Shaodong;Lu Liping;Zhu Miaoli;Yuan Caixia;Feng Sisi
29 Synthesis, Crystal Structure and Protein Tyrosine Phosphatase Inhibition of a Copper(II) Complex with N-(2-Pyridylmethyl)-L-serine 期刊论文 Li Yanhong;Yuan Caixia;Lu Liping;Zhu Miaoli;Fu Xueqi;Xing Shu;Gao Zengqiang
30 CBe(5)H(n)n-4 (n=2-5): Hydrogen-Stabilized CBe5 Pentagons Containing Planar or Quasi-Planar Pentacoordinate Carbons 期刊论文 Guo Jin-Chang;Ren Guang-Ming;Miao Chang-Qing;Tian Wen-Juan;Wu Yan-Bo;Wang Xiaotai
31 一种钴金属有机骨架材料及其制备方法和应用 专利 卢丽萍;李少东;冯思思;朱苗力
32 Stabilization of beryllium-containing planar pentacoordinate carbon species through attaching hydrogen atoms 期刊论文 Zhao Xue Feng;Bian Jian Hong;Huang Fang;Yuan Caixia;Wang Qiang;Liu Ping;Li Debao;Wang Xiaotai;Wu Yan Bo
33 Evaluation of Cu(II) Complexes with Schiff Base of Salicylanilide as the Inhibitors of Protein Tyrosine Phosphatases 期刊论文 Yuan Cai-Xia;Lan Shu-Fen;Lu Li-Ping
34 4-(1H-Indol-3-yl)-2,6-bis(pyrazin-2-yl)pyridine 期刊论文 Wang Jianwei;Yuan caixia
35 Syntheses, structures, magnetic properties and luminescence of four coordination polymers based on an asymmetric semirigid tricarboxylate ligand 期刊论文 Shaodong Li;Liping Lu;Sisi Feng;Miaoli Zhu
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