3D打印改性PCL/凝胶双相支架负载hWJ-MSC来源外泌体促进纤维环缺损修复及其机制研究

81871782
2018
H0604.骨、关节、软组织损伤与修复
杨强
面上项目
主任医师
天津市天津医院
57万元
纤维环;组织工程;支架;3D打印;外泌体
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Immunomodulation of MSCs and MSC-Derived Extracellular Vesicles in Osteoarthritis 期刊论文 Xige Zhao;Yanhong Zhao;Xun Sun;Yi Xing;Xing Wang;Qiang Yang
2 天津市“131”创新型人才团队 奖励 杨强;马信龙;马剑雄;明东;赵强;王涛;刘军;陈超;刘璐;杨阳;孙逊
3 Pretreated Mesenchymal Stem Cells and Their Secretome: Enhanced Immunotherapeutic Strategies 期刊论文 Yuran Su;Chenyu Xu;Wen Cheng;Yanmei Zhao;Lei Sui;Yanhong Zhao
4 Targeted fully endoscopic visualized laminar trepanning approach under local anaesthesia for resection of highly migrated lumbar disc herniation 期刊论文 Chao Chen;Xun Sun;Jie Liu;Xinlong Ma;Dong Zhao;Haiyun Yang;Gang Liu;Baoshan Xu;Zheng Wang;Qiang Yang
5 Tunable Multiple Morphological Transformation of Supramolecular Hyperbranched Polymers Based on an A2B6-type POSS Monomer 期刊论文 Linfeng Fan;Cui-Ling Hou;Xing Wang;Li-Tang Yan;Decheng Wu
6 Facile fabrication of a biocompatible composite gel with sustained release of aspirin for bone regeneration 期刊论文 Yunfan Zhang;Xueyu Dou;Lingyun Zhang;Hufei Wang;Ting Zhang;Rushui Bai;Qiannan Sun;Xing Wang;Tingting Yu;Decheng Wu;Bing Han;Xuliang Deng
7 The Immuno-Modulation Effect of Macrophage-Derived Extracellular Vesicles in Chronic Inflammatory Diseases. 期刊论文 Xing Yi;Sun Xun;Dou Yiming;Wang Min;Zhao Yanmei;Yang Qiang;Zhao Yanhong
8 一种新型颈椎侧块螺钉固定结构 专利 杨强;马信龙;代亚男;何田田;甄超;张勋
9 侧前方入路椎间融合器 专利 杨强;马信龙;王征;张一鸣;甄超;张勋
10 一种纤维环部分切除椎间盘退变或缺损造模器 专利 杨强;马信龙;狄鸣远;窦一鸣;赵志刚;张为;刘杰
11 Can the Full-Percutaneous Endoscopic Lumbar Discectomy in Day Surgery Mode Achieve Better Outcomes Following Enhanced Recovery after Surgery Protocol? A Retrospective Comparative Study 期刊论文 Le Kou;Wentao Wan;Chao Chen;Dong Zhao;Xun Sun;Ziwei Gao;Hongjin Wu;Mingyuan Di;Xinlong Ma;Baoshan Xu;Jun Miao;Zheng Wang;Qiang Yang
12 Poly(N-isopropyl-acrylamide)/poly (γ-glutamic acid) thermo-sensitive hydrogels loaded with superoxide dismutase for wound dressing application 期刊论文 Yunsheng Dong;Huahong Zhuang;Yan Hao;Lin Zhang;Qiang yang;Yufei Liu;Chunxiao Qi;Shufang Wang
13 Full Endoscopic Lumbar Foraminoplasty with Periendoscopic Visualized Trephine Technique for Lumbar Disc Herniation with Migration and/or Foraminal or Lateral Recess Stenosis 期刊论文 Chen Chao;Ma Xinlong;Zhao Dong;Yang Haiyun;Xu Baoshan;Wang Zheng;Yang Qiang
14 Biomechanical study of oblique lumbar interbody fusion (OLIF) augmented with different types of instrumentation: a finite element analysis 期刊论文 Xin-Yi Cai;Han-Ming Bian;Chao Chen;Xin-Long Ma;Qiang Yang
15 Recent Trends in the Development of Bone Regenerative Biomaterials 期刊论文 Guoke Tang;Zhiqin Liu;Yi Liu;Jiangming Yu;Xing Wang;Zhihong Tan;Xiaojian Ye
16 第 2 骶椎骶髂螺钉固定骶骨骨盆的优势及意义 期刊论文 刘钢;杨强;郝永宏;邓树才
17 一种藕状梯度孔隙结构的多孔钛合金腰椎椎间融合器 专利 杨强;张存;马信龙;王征;杨磊;梁春永;刘璐;孙逊
18 An Ultrashort Peptide-Based Supramolecular Hydrogel Mimicking IGF-1 to Alleviate Glucocorticoid-Induced Sarcopenia. 期刊论文 Shang Yuna;Kuang Mingjie;Wang Zhongyan;Huang Ying;Liu Lulu;Zhao Xige;Zhang Rui;Zhao Yanhong;Peng Rong;Sun Shenghuan;Yang Qiang;Yang Zhimou
19 缓释双生长因子的含钙化层骨软骨支架及其制备方法 专利 王淑芳;杨强;董云生;赵艳红;马信龙;李云洁;张琳
20 一种骨水泥锚定器组件 专利 杨强;马信龙
21 一种双层仿生人工骨膜及其制备方法和应用 专利 杨强;刘文广;孙雅格;高梓唯;窦一鸣;刘潞兴;刘洋;狄鸣远
22 可动式椎间盘镜的关键技术创新与临床应用 奖励 徐宝山;许海委;杜立龙;刘越;马信龙;姜洪丰;黎宁;杨强
23 Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies 期刊论文 Yiming Dou;Xun Sun;Xinlong Ma;Xin Zhao;Qiang Yang
24 Engineering a biomimetic integrated scaffold for intervertebral disc replacement. 期刊论文 Du Lilong;Yang Qiang;Zhang Jiamin;Zhu Meifeng;Ma Xinlong;Zhang Yang;Wang Lianyong;Xu Baoshan
25 Regional and sustained dual -release of growth factors from biomimetic tri-layered scaffolds for the repair of large-scale osteochondral defects 期刊论文 Dong Yunsheng;Sun Xun;Zhang Zhiling;Liu Yufei;Zhang Lin;Zhang Xiangyun;Huang Ying;Zhao Yanhong;Qi Chunxiao;Midgley Adam C.;Wang Shufang;Yang Qiang
26 含钙化层的取向全层软骨支架及其制备方法 专利 王淑芳;董云生;杨强;张祥云
27 Role of the Calcified Cartilage Layer of an Integrated Trilayered Silk Fibroin Scaffold Used to Regenerate Osteochondral Defects in Rabbit Knees 期刊论文 Zhao Yanhong;Ding Xiaoming;Dong Yunsheng;Sun Xun;Wang Lianyong;Ma Xinlong;Zhu Meifeng;Xu Baoshan;Yang Qiang
28 天津市创新人才推进计划中青年科技创新领军人才 奖励 杨强
29 Effects of osteoporosis on the biomechanics of various supplemental fixations co-applied with oblique lumbar interbody fusion (OLIF): a finite element analysis 期刊论文 Zi-Xuan Liu;Zi-Wei Gao;Chao Chen;Zi-Yang Liu;Xin-Yi Cai;Ya-Nan Ren;Xun Sun;Xin-Long Ma;Cheng-Fei Du;Qiang Yang
30 Wharton's jelly MSC-derived extracellular vehicles—loaded hyaluronic acid-alginate adhesives for treatment of osteoarthritis 期刊论文 Yanhong Zhao;Xige Zhao;Hainan Xu;Yi Xing;Tengling Wu;Xun Sun;Mingjie Kuang;Xinlong Ma;Wenguang Liu;Qiang Yang
31 Synergistic Effects of Kartogenin and Transforming Growth Factor-β3 on Chondrogenesis of Human Umbilical Cord Mesenchymal Stem Cells In Vitro. 期刊论文 Zhao Yanhong;Teng Binhong;Sun Xun;Dong Yunsheng;Wang Shufang;Hu Yongcheng;Wang Zheng;Ma Xinlong;Yang Qiang
32 一种胸腰椎手术术前、术中定位器 专利 杨强;马信龙;谢梦琦;王征;孙逊;陈超
33 锚定器 专利 马信龙;杨强
34 骨髓间充质干细胞来源外泌体对炎症微环境中巨噬细胞 表型及软骨细胞的调控作用 期刊论文 邢轶;窦一鸣;王敏;徐海楠;杨强;孙逊;赵艳红
35 Comparative radiological outcomes and complications of sacral-2-alar iliac screw versus iliac screw for sacropelvic fixation 期刊论文 Ziwei Gao;Xun Sun;Chao Chen;Zhaowei Teng;Baoshan Xu;Xinlong Ma;Zheng Wang;Qiang Yang
36 Cross-talk Between Histone and DNA Methylation Mediates Bone Loss in Hind Limb Unloading. 期刊论文 Li Bing;Zhao Jie;Ma Jianxiong;Chen Weibo;Zhou Ce;Wei Wuzeng;Li Shuai;Li Guomin;Xin Guosheng;Zhang Yang;Liu Jun;Wang Yinsong;Ma Xinlong
37 Comparative analysis of the biomechanics of the adjacent segments after minimally invasive cervical surgeries versus anterior cervical discectomy and fusion: A finite element study. 期刊论文 Chen Chao;Yuchi Chen-Xi;Gao Ziwei;Ma Xinlong;Zhao Dong;Li Jun-Wei;Xu Baoshan;Zhang Chun-Qiu;Wang Zheng;Du Cheng-Fei;Yang Qiang
38 Doping bioactive elements into a collagen scaffold based on synchronous self-assembly/mineralization for bone tissue engineering. 期刊论文 Liu Huanhuan;Lin Mingli;Liu Xue;Zhang Ye;Luo Yuyu;Pang Yanyun;Chen Haitao;Zhu Dongwang;Zhong Xue;Ma Shiqing;Zhao Yanhong;Yang Qiang;Zhang Xu
39 Endplate volumetric bone mineral density biomechanically matched interbody cage 期刊论文 Yuanzhi Weng;Mingyuan Di;Tianchi Wu;Xinlong Ma;Qiang Yang;Weijia William Lu
40 High efficacy of tetra-PEG hydrogel sealants for sutureless dural closure 期刊论文 Tengjiao Zhu;Hufei Wang;Zehao Jing;Daoyang Fan;Zhongjun Liu;Xing Wang;Yun Tian
41 一种可撑开椎间植入物 专利 杨强;马信龙;许书富;程磊;王卡;甄超;张勋;董骧
42 椎体修复套件 专利 张为;李严;黎庆初;杨强;孙亚鹏;李佳奇;张飞;郭磊
43 一种骶骨螺钉固定结构 专利 杨强;马信龙;代亚男;何田田;甄超;张勋
44 小面关节固定系统 专利 杨强;马信龙;王征;代亚男;甄超;张勋
45 一种用于抗炎和促组织再生的巨噬细胞来源外泌体制剂及其制备方法和应用 专利 杨强;赵艳红;邢轶;马信龙;窦一鸣;杨磊;孙逊;王敏;赵昕
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