构建骨髓增生异常综合征/继发性白血病小鼠动物模型及其造血干细胞克隆演变机制研究
81470338
2014
H0809.白血病
张悦
面上项目
副教授
中国医学科学院
70万元
克隆演变;动物模型;继发性白血病;发病机制;骨髓增生异常综合症
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development | 会议论文 | Yoshihiro Hayashi;Yue Zhang;Xiaomei Yan;Kwangmin Choi;Goro Sashida;Yunzhu Dong;Zefeng Xu;Lingyun Wu;Aili Chen;Xiujuan Sun;Andre Olsson;Hironori Harada;Lee-Yung Shih;William Tse;James Bridges;David P Wang;Qianfei Wang;Michael A. Caligiuri;H.Leighton Grimes;Stephen D.Nimer;Zhijian Xiao;Gang Huang |
| 2 | Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models | 期刊论文 | Wang Jieyu;Hayashi Yoshihiro;Yokota Asumi;Xu Zefeng;Zhang Yue;Huang Rui;Yan Xiaomei;Liu Hongyun;Ma Liping;Azam Mohammad;Bridges James P.;Cancelas Jose A.;Kalfa Theodosia A.;An Xiuli;Xiao Zhijian;Huang Gang |
| 3 | A novel fusion of PDGFRB to TSC1, an intrinsic suppressor of mTOR-signaling pathway, in a chronic eosinophilic leukemia patient with t(5;9)(q32;q34) | 期刊论文 | Yue Zhang;Shiqiang Qu;Qianfei Wang;Jianyong Li;Zefeng Xu;Tiejun Qin;Gang Huang;Zhijian Xiao |
| 4 | Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes | 期刊论文 | Hayashi Yoshihiro;Zhang Yue;Yokota Asumi;Yan Xiaomei;Liu Jinqin;Choi Kwangmin;Li Bing;Sashida Goro;Peng Yanyan;Xu Zefeng;Huang Rui;Zhang Lulu;Freudiger George M;Wang Jingya;Dong Yunzhu;Zhou Yile;Wang Jieyu;Wu Lingyun;Bu Jiachen;Chen Aili;Zhao Xinghui;Sun Xiujuan;Chetal Kashish;Olsson Andre;Watanabe Miki;Romick Rosendale Lindsey E;Harada Hironori;Shih Lee Yung;Tse William;Bridges James P;Caligiuri Michael A... |
| 5 | 端粒酶抑制剂伊美司他治疗骨髓增殖性肿瘤的研究进展与展望 | 期刊论文 | 颜呈呈;张悦 |
| 6 | 慢性嗜中性粒细胞白血病:新基因突变对诊断及治疗选择的影响 | 期刊论文 | 张悦 |
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