骨髓增生异常综合征和骨髓增殖性肿瘤合并骨髓纤维化作用机制研究
81470297
2014
H0808.骨髓增殖性肿瘤
黄刚
面上项目
副教授
中国医学科学院
75万元
骨髓增生异常综合征;骨髓增殖性肿瘤;发病机制;骨髓纤维化
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A novel fusion of PDGFRB to TSC1, an intrinsic suppressor of mTOR-signaling pathway, in a chronic eosinophilic leukemia patient with t(5;9)(q32;q34) | 期刊论文 | Yue Zhang;Shiqiang Qu;Qianfei Wang;Jianyong Li;Zefeng Xu;Tiejun Qin;Gang Huang;Zhijian Xiao |
| 2 | Bone marrow fibrosis grade is an independent riskfactor for overall survival in patients with primary myelofibrosis. | 期刊论文 | Li B;Zhang P;Feng G;Xu Z;Qin T;Zhang Y;Sha Z;Dong D;Zhang H;Fang L;Pan L;Hu N;Qu S;Cai W;Gang Huang;Xiao Z |
| 3 | The different prognostic impact of type-1 or type-1like and type-2 or type-2 like CALR mutations in patients with primarymyelofibrosis | 期刊论文 | Li B;Xu Z;Li Y;Peter Gale R;Song Z;Ai X;Qin T;Zhang Y;Zhang P;Gang Huang;Xiao Z |
| 4 | HIF1A is a critical downstream mediator for hemophagocytic lymphohistiocytosis | 期刊论文 | Huang Rui;Hayashi Yoshihiro;Yan Xiaomei;Bu Jiachen;Wang Jieyu;Zhang Yue;Zhou Yile;Tang Yuting;Wu Lingyun;Xu Zefeng;Liu Xin;Wang Qianfei;Zhou Jianfeng;Xiao Zhijian;Bridges James P;Marsh Rebecca A;Zhang Kejian;Jordan Michael B;Li Yuhua;Huang Gang |
| 5 | EPO Signaling Triggers Erythrocytosis By Expanding Erythrocytes and Also Subsets of Macrophages | 会议论文 | Yoshihiro Hayashi;Jieyu Wang;Zefeng Xu;Xiaomei Yan;Yue Zhang;Theodosia A Kalfa;Zhijian Xiao;Gang Huang |
| 6 | Pathobiological Pseudohypoxia as a Putative Mechanism Underlying Myelodysplastic Syndromes | 期刊论文 | Yoshihiro Hayashi;Gang Huang |
| 7 | Impact of TET2, SRSF2, ASXL1 and SETBP1 mutations on survival of patients with chronic myelomonocytic leukemia | 期刊论文 | Cui Yajuan;Tong Hongyan;Du Xin;Li Bing;Gale Robert Peter;Qin Tiejun;Liu Jinqin;Xu Zefeng;Zhang Yue;Huang Gang;Jin Jie;Fang Liwei;Zhang Hongli;Pan Lijuan;Hu Naibo;Qu Shiqiang;Xiao Zhijian |
| 8 | Expansion of EPOR-negative macrophages besides erythroblasts by elevated EPOR signaling in erythrocytosis mouse models | 期刊论文 | Wang J;Hayashi Y;Yokota A;Xu Z;Zhang Y;Huang R;Yan X;Liu H;Azam M;Bridges JP;Cancelas JA;Kalfa TA;An X;Xiao Z;Huang G |
| 9 | HIF-1a Pathway, As a Signal Funnel for Genetic, Epigenetic, and Metabolic Aberrations, Is Sufficient and Essential for MDS Development | 会议论文 | Yoshihiro Hayashi;Yue Zhang;Xiaomei Yan;Kwangmin Choi;Goro Sashida;Yunzhu Dong;Zefeng Xu;Lingyun Wu;Aili Chen;Xiujuan Sun;Andre Olsson;Hironori Harada;Lee-Yung Shih;William Tse;James Bridges;David P Witte;Qianfei Wang;Michael A. Caligiuri;H. Leighton Grimes;Stephen D. Nimer;Zhijian Xiao;Gang Huang |
| 10 | Activation of HIF-2a-EPO Axis in Kidney or Liver Is Sufficient to Drive Erythrocytosis in a Novel Inducible HIF-2a Transgenic Mouse Model | 会议论文 | Jieyu Wang;Yoshihiro Hayashi;Zefeng Xu;Lingyun Wu;Xiaomei Yan;Theodosia A. Kalfa;Zhijian Xiao;Gang Huang |
| 11 | Multiplex ligation-dependent probe amplification assay identifies additional copy number changes compared with R-band karyotype and provide more accuracy prognostic information in myelodysplastic syndromes | 期刊论文 | Wang Jingya;Ai Xiaofei;Qin Tiejun;Xu Zefeng;Zhang Yue;Liu Jinqin;Li Bing;Fang Liwei;Zhang Hongli;Pan Lijuan;Hu Naibo;Qu Shiqiang;Cai Wenyu;Ru Kun;Jia Yujiao;Huang Gang;Xiao Zhijian |
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