p16INK4a-STAT3通路调控角膜上皮干细胞衰老及其在角膜上皮损伤修复中的作用

81670828
2016
H1301.角膜及眼表疾病
杨玲玲
面上项目
研究员
山东第一医科大学
58万元
STAT3;角膜上皮干细胞;损伤修复;衰老;p16INK4a
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The proinflammatory cytokines IL-1β and TNF-α modulate corneal epithelial wound healing through p16 suppressing STAT3 activity 期刊论文 Xiaolei Wang;Songmei Zhang;Muchen Dong;Yunqiu Li;Qingjun Zhou;Lingling Yang
2 MANF Promotes Diabetic Corneal Epithelial Wound Healing and Nerve Regeneration by Attenuating Hyperglycemia-Induced Endoplasmic Reticulum Stress 期刊论文 Xiaochuan Wang;Weina Li;Qingjun Zhou;Jing Li;Xiaolei Wang;Jing Zhang;Dewei Li;Xia Qi;Ting Liu;Xiaowen Zhao;Suxia Li;Lingling Yang;Lixin Xie
3 LRG1 promotes corneal angiogenesis and lymphangiogenesis in a corneal alkali burn mouse model 期刊论文 Song Shan;Cheng Jun;Yu Bing-Jie;Zhou Li;Xu Hai-Feng;Yang Ling-Ling
4 Corneal Denervation Causes Epithelial Apoptosis Through Inhibiting NAD+ Biosynthesis 期刊论文 Ya Li;Xiubin Ma;Jing Li;Lingling Yang;Xiaowen Zhao;Xia Qi;Xiaoping Zhang;Qingjun Zhou;Weiyun Shi
5 Different Effects of Pro-Inflammatory Factors and Hyperosmotic Stress on Corneal Epithelial Stem/Progenitor Cells and Wound Healing in Mice 期刊论文 Lingling Yang;Songmei Zhang;Haoyun Duan;Muchen Dong;Xiaoli Hu;Zhaohua Zhang;Yao Wang;Xiaoping Zhang;Weiyun Shi;Qingjun Zhou
6 Leucine-rich α-2-glycoprotein-1 promotes diabetic corneal epithelial wound healing and nerve regeneration via regulation of matrix metalloproteinases 期刊论文 Weina Li;Xiaochuan Wang;Jun Cheng;Jing Li;Qun Wang;Qingjun Zhou;Hua Li;Junfa Xue;Yuan Zhang;Lingling Yang;Lixin Xie
7 Induction of Fibroblast Senescence During Mouse Corneal Wound Healing. 期刊论文 xiaolei wang;Mingli qu;Jing Li;Danielson P;Lingling Yang;Qingjun Zhou
8 MANF在促进角膜损伤修复中的应用 专利 杨玲玲;王晓川;李维钠;谢立信
9 Hyperglycemia-reduced NAD + biosynthesis impairs corneal epithelial wound healing in diabetic mice 期刊论文 Ya Li;Jing Li;Can Zhao;Lingling Yang;Xia Qi;Xiaochuan Wang;Qingjun Zhou;Weiyun Shi
10 Insulin Promotes Corneal Nerve Repair and Wound Healing in Type 1 Diabetic Mice by Enhancing Wnt/β-Catenin Signaling. 期刊论文 Shuo Yang;Yangyang Zhang;Zhaohua Zhang;Jing Dan;Qingjun Zhou;Xiaochuan Wang;Weina Li;Li Zhou;Lingling Yang;Lixin Xie
11 一种构建组织工程角膜缘的方法 专利 周庆军;董沐晨;史伟云;杨玲玲;段豪云
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