基于纳米磁分离的多样本多位点高通量核酸分析系统及其关键技术研究

60927001
2009
F0124.生物电子学与生物信息处理
何农跃
专项基金项目
教授
东南大学
150万元
核酸突变;单核苷酸多态性;荧光ddNPT单碱基循环延伸;多样本多位点高通量;分子诊断
2010-01-01到2012-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Therapy for Cerebral Ischemic Injury with Erythropoietin-Containing Nanoparticles 期刊论文 He, Nongyue|Wang, Ting|Jiang, Li|Wang, Daxin|Hu, Yan|Zhang, Long|
2 全自动核酸分子诊断系统的某些进展 期刊论文 刘宾|覃斌兵|刘洪娜|何农跃|
3 基于磁分离与生物芯片技术的高通量核酸分析集成系统 会议论文 何农跃|
4 New advances of application of magnetic nanoparticles in high throughput SNP genotyping 会议论文 He, Nongyue|Jia, Yingying|Mou, Xianbo|Liu, Hongna|Li, Song|
5 Synthesis of Size-Controlled Fe3O4@SiO2 Magnetic Nanoparticles for Nucleic Acid Analysis 期刊论文 Sun, Huanxiang|Zeng, Xin|Liu, Ming|Elingarami, Sauli|Li, Guopeng|Shen, Bin|He, Nongyue|
6 Preparation of Functionial Magnetic Nanoparticles Mediated with PEG 4000 and Application in Pseudomonas aeruginosa Rapid Detection 期刊论文 Yongjun Tang, et al|Nongyue He|
7 Fabrication and characterization of streptavidin gamma-Fe2O3@Au nanocomposites for biological application 会议论文 He, Nongyue|Wang, Fang|Liu, Lishang|Liu, Bin|Liu, Hongna|Li, Song|
8 Preparation of carboxyl group-modified palladium nanoparticles in an aqueous solution and their conjugation with DNA 期刊论文 Wang, Zhifei|Li, Hongying|Zhen, Shuang|He, Nongyue|
9 Electrochemical Detection of E. coli O157:H7 Using Porous Pseudo-Carbon Paste Electrode Modified with Carboxylic Multi-Walled Carbon Nanotubes, Glutaraldehyde and 3-Aminopropyltriethoxysilane 期刊论文 Lijian Xu, et al|Nongyue He|
10 多孔“类碳糊电极”的羧基化及其对Escherichia ocli O157:H7的检测 期刊论文 许利剑|杜晶晶|邓燕|李智洋|徐春祥|何农跃|汪华|史智扬|
11 Erythropoietin Nanopariticles: Therapy for Cerebral Ischemic Injury and Metabolize in Kidney and Liver 期刊论文 Ting Wang|Yan Hu|Long Zhang|Li Jiang|Zhan Chen|Nongyue He|
12 Preparation, characterization and applications of low-molecular-weight alginate-oligochitosan nanocapsules 期刊论文 Wang, Ting, et al|He, Nongyue|
13 Highly Sensitive and Rapid Detection of Pseudomonas aeruginosa Based on Magnetic Enrichment and Magnetic Separation 期刊论文 Yongjun Tang, et al|Nongyue He|
14 A novel automated assay with dual-color hybridization for single-nucleotide polymorphisms genotyping on gold magnetic nanoparticle array 期刊论文 Li, Song|Liu, Hongna|Liu, Lishang|Tian, Lan|He, Nongyue|
15 带震动装置的全温液相颗粒孵育及杂交仪 专利 刘宾; 李智洋; 何农跃
16 基于磁分离与高保真酶校正功能的核酸序列分析方法 专利 *何农跃; 曾新
17 全温微体积混匀孵育及杂交仪 专利 李智洋; *何农跃; 黄瑾; 刘宾
18 Application of magnetic nanoparticles in high-throughput single nucleotide polymorphisms (SNPs) and copy number variations (CNVs) analysis 会议论文 何农跃|
19 An Automatic High-Throughput Single Nucleotide Polymorphism Genotyping Approach Based on Universal Tagged Arrays and Magnetic Nanoparticles 期刊论文 Song Li|Hongna Liu|Yingying Jia|Xianbo Mou|Yan Deng|Lin Lin|Bin Liu|Nongyue He|
20 Preliminary Studies on Palladium Nanoparticle as a Novel Label for DNA Microarray and Their Corresponding Detection 期刊论文 Zhifei Wang, et al|Nongyue He|
21 基于磁性颗粒微阵列与双色荧光杂交的单核苷酸多态性分型方法研究 期刊论文 刘洪娜|李松|刘丽赏|田岚|贾英英|李智洋|邓燕|何农跃|
22 Preparation and Electrochemical Behavior of L-glutamate Electrochemical Biosensor 期刊论文 Yan Deng, et al|Yan Deng|
23 Research of the Incubation and Hybridization Instrument with Vibration for Nanoparticles 期刊论文 Zheng Liu|Yan Deng, et al|Nongyue He|
24 Progress of Research in Gastric Cancer 期刊论文 Zeeshan Ali|Yan Deng|Chao Ma|
25 功能化掺杂介孔材料设计、制备、性质与应用研究 奖励 何农跃|葛树勋|匡跃平|,曹洁明|,须沁华|
26 基于磁分离和光学检测的分子诊断新方法及相关仪器的研发 会议论文 李智洋|
27 基于纳米技术的高通量自动化单碱基差异检测方法研究 奖励 刘洪娜|
28 A Novel SNPs Detection Method Based on Gold Magnetic Nanoparticles Array and Single Base Extension 期刊论文 Song Li et al.|Nongyue He|
29 Synthesis and Characterization of Fe3O4@SiO2 Core-Shell Magnetic Microspheres for Extraction of Genomic DNA from Human Whole Blood 期刊论文 Li, Guopeng|Shen, Bin|He, Nongyue|Ma, Chao|Elingarami, Sauli|Li, Zhiyang|
30 High-throughput SNPs detection system based magnetic separation 会议论文 Liu, Bin|He, Nongyue|Qin, Binbing|
31 Single nucleotide polymorphisms genotyping using solid-phase single base extension on magnetic nanoparticles 会议论文 何农跃|
32 一种呈微米级立方体的超分散四氧化三铁颗粒的制备方法 专利 何农跃; 李小龙; 李智洋; 李国鹏
33 三层核壳结构金磁纳米颗粒的制备方法 专利 *何农跃; 江红荣; 曾新; 王婷
34 Single nucleotide polymorphisms genotyping using solid-phase single base extension on magnetic nanoparticles 会议论文 N. Y. He|
35 带震动功能的全温液相颗粒孵育及杂交装置 专利 李智洋; 刘宾; *何农跃
36 New Perspective of GABA as an Inhibitor of Formation of Advanced Lipoxidation End-Products: It’s Interaction with Malondiadehyde 期刊论文 Deng, Yan|Xu, Lijian|Jiang, Huanmei|Li,Zhiyang|Liu, Hongna|Qin, Binbing|He, Nongyue|
37 用于生物检测的链霉亲和素修饰γ-Fe_2O_3@Au复合颗粒的制备与表征 期刊论文 刘丽赏|刘洪娜|李松|邓燕|李小龙|何农跃|
38 High Throughput SNP Detection System Based on Magnetic Nanoparticles Separation 期刊论文 Bin Liu, et al|Nongyue He|
39 Green Synthesis of Uniform Magnetite (Fe3O4) Nanoparticles and Micron Cubes 期刊论文 Li, Xiaolong|Zhang, Fengqin|Ma, Chao|Saul, Elingarami|He, Nongyue|
40 Preparation and Biomedical Applications of Core-Shell Silica/Magnetic Nanoparticle Composites 期刊论文 Li, Chuanyan|Ma, Chao|Wang, Fang|Xi, Zhijiang|Wang, Zhifei|Deng, Yan|He, Nongyue|
41 Preparation and Characterization of Porous Electrochemical Sensor and Its Application in Voltammetric Determination of Paracetamol 期刊论文 Nongyue He, et al|
42 Magnetic Nanoparticles-Based Extraction and Verification of Nucleic Acids from Different Sources 期刊论文 Chao Ma, et al|Nongyhue He|
43 Advance in Applications of Dendritic Compounds 期刊论文 Ningning Ma|Chao Ma|Ting Wang|Yan Deng|Nongyue He|
44 Current Advances in Combinatorial Chemistry Application in Biochips Nanotechnology 期刊论文 Sauli Elingarami|Zunliang Wang|Xin Zeng|
45 Current advances in high throughput SNP genotyping based on magnetic nanoparticles 会议论文 何农跃|
46 基于蛋白质芯片的TORCH检测新技术的研究 奖励 蒋犁|余章斌|陆祖宏|何农跃|张春秀|
47 An Automated MagStation for High-Throughput Single Nucleotide Polymorphism Genotyping and the Dual-Color Hybridization 期刊论文 Lan Tian|Song Li, et al|Nongyue He|
48 基于磁分离的多样本多位点高通量核酸分析系统 专利 *何农跃; 刘宾; 李松; 刘铮; 李智洋; 陈慧; 刘洪娜
49 基于磁分离与引物延伸的化学发光检测拷贝数多态性的方法 专利 曾新; 何农跃; 柳明
50 Preparation and Characterization of Monodisperse Core-Shell Fe3O4 @ SiO2 Microspheres and Its Application for Magnetic Separation of Nucleic Acids from E. coli BL21 期刊论文 Chao Ma, et al.|Nongyue He|
51 Chemiluminescence Analysis for HBV-DNA Hybridization Detection with Magnetic Nanoparticles based DNA Extraction from Positive Whole Blood Samples, 期刊论文 Nongyue He et al.|
52 东南大学第七届大学生创业计划竞赛暨第七届“挑战杯”全国大学生创业计划竞赛东南大学校内选拔赛 奖励 刘宾|
53 Current advances in high throughput SNP genotyping based on magnetic nanoparticle bead-array 会议论文 何农跃|
54 Integrated detection system development for biomacromolecules based on magnetic separation 会议论文 何农跃|
55 Research of Temperature Control Algorithm in PCR Gene Amplify Instrument 会议论文 Bin Liu, et al|Nongyue He|
56 基于物联网的社区空气质量检测系统 奖励 程铅|杜宇航|马嫚|刘铮|张博博|陈慧|夏云|李其花|
57 Molecular Dynamics Simulations of End-Tethered Single-Stranded DNA Probes on a Silica Surface 期刊论文 Wang, Zunliang|Zeng, Xin|Deng, Yan|He, Nongyue|Wang, Qiong|Huang, Jianguo|
58 基于蛋白质微阵列方法对TORCH感染检测新的技术研究 奖励 蒋犁|余章斌|陆祖宏|何农跃|张春秀|张茜|
59 基于磁分离的高通量SNP分型系统及相关试剂盒 奖励 刘宾|
60 Surface-Engineered Magnetic Nanoparticles for Molecular Detection of Infectious agents and Cancer: Current Advances 期刊论文 Sauli Elingarami|Nongyue He, et al|
61 A system for nucleic acid quantification based on magnetic nanoparticles and chemiluminescence by ligation-dependent PCR 会议论文 Ming Liu|Xin Zeng|Nongyue He|
62 Long term consequences of erythropoietin nanocarriers single treatment for periventricular leukomalacia rats’ model 奖励 王婷|
63 全温微体积混匀孵育及杂交仪 专利 *何农跃; 李智洋; 黄谨; 刘宾
64 Single Lipid Bilayers Constructed on Polymer Cushion Studied by Sum Frequency Generation Vibrational Spectroscopy 期刊论文 Wang, Ting|Chen, Zhan|Li, Dawei|Lu, Xiaolin|Khmaladze, Alexander|Han, Xiaofeng|Ye, Shuji|Yang, Pei|Xue, Gi|He, Nongyue|
65 An integrated and sensitive detection platform for biosensing application based on Fe@Au magnetic nanoparticles as bead array carries 期刊论文 Hongna Liu, et al.|Nongyue He|
66 Applications of Magnetic Nanoparticles for Bio-Separation, Sequencing, Diagnosis and Drug Delivery 期刊论文 Sauli Elingarami|Xin Zeng, et al|
67 Current Advance in Development of the Integrated System for High-throughput Nucleotide Analysis Based on Magnetic Separation 会议论文 何农跃|
68 基于物联网的老年人跌倒监测系统 奖励 刘铮|张博博|陈慧|夏云|
69 基于蛋白质微阵列方法对TORCH感染检测新的技术研究 奖励 蒋犁|余章斌|陆祖宏|何农跃|张春秀|张茜|
70 Erythropoietin-loaded oligochitosan nanoparticles for treatment of periventricular leukomalacia 期刊论文 Wang, Ting|Hu, Yan|Leach, Michelle K.|Zhang, Long|Yang, Wenjing|Jiang, Li|Feng, Zhang-Qi|He, Nongyue|
71 Conditions of PCR Amplification by Magnetic Enrichment and Nanoscale Detection Sensitivity 期刊论文 Nongyue He, et al|
72 Controllable Synthesis of ZnO with Various Morphologies by Hydrothermal Method 期刊论文 Xiaolong Li, et al|Nongyue He|
73 高通量磁分离系统及应用 奖励 刘宾|张博博|江红荣|
74 Application of Solid-State NMR in Characterization of Bone Related Tissue Engineering 期刊论文 He, Nongyue|Elingarami, Sauli|Zhu, Peizhi|
75 The State of Field of High-throughput SNP Genotyping System 会议论文 Zheng Liu|Bin Liu|Yan Deng|Nongyue He|
76 Development of a Total Temperature Micro-Volume Blended Incubating and Hybridizing Apparatus for DNA Hybridization on Nanoparticles 期刊论文 Bin Liu, et al.,|Nongyue He|
77 Fabrication and Characterization of Nanoporous Pseudo-Carbon Paste Electrode 期刊论文 Xu, Lijian|Du, Jingjing|Deng, Yan|Li, Zhiyang|Xu, Chunxiang|He, Nongyue|
78 High−throughput single nucleotide polymorphisms (SNPs) detection and copy number variations (CNVs) analysis with the help of magnetic nanoparticles 会议论文 何农跃|
79 Preparation of Silicotungstenic Acid-Containing Mesoporous Materials 期刊论文 Nongyue He et al|
80 一种凝胶软膏制剂及其制备方法 专利 王婷; 何农跃
81 磁性多孔化学电极的制备方法 专利 何农跃; 许利剑; 李智洋; 邓燕; 杜晶晶
82 低荧光背景的组装型金磁复合纳米颗粒的制备方法及其应用 专利 *何农跃; 曾新; 江红荣; 李传燕
83 Preparation of SiO2/(PMMA/Fe3O4) Nanoparticles Using Linolenic Acid as Cross link Agent for Nucleic Acid Detection Using Chemiluminescent Method 期刊论文 He, Lei|Li, Zhiyang|Fu, Jing|Wang, Fang|Ma, Chao|Deng, Yan|Shi, Zhiyang|Wang, Hua|He, Nongyue|
84 Polymerase Chain Reaction Coupling with Magnetic Nanoparticles-Based Biotin-Avidin System for Amplification of Chemiluminescent Detection Signals of Nucleic Acid 期刊论文 Li, Zhiyang|Wang, Daxin|He, Lei|He, Nongyue|Deng, Yan|Shi, Zhiyang|Wang, Hua|Li, Song|Liu, Hongna|Wang, Zhifei|
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