构建肽核酸编码的α-芋螺毒素肽二硫键模拟物文库
21807001
2018
B0702.生物分子的化学生物学
方葛敏
青年科学基金项目
教授
安徽大学
25万元
固相合成;蛋白质化学;多肽化学;组合化学
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Helix-Constrained Peptides Constructed by Head-to-Side Chain Cross-Linking Strategies | 期刊论文 | Xiao-Xu Chen;Tang Yang;Meng Wu;Yan-Ni Zhang;Kai Chen;Zhaocai Zhou;Ge-Min Fang |
| 2 | Head-to-Tail Cross-Linking to Generate Bicyclic Helical Peptides with Enhanced Helicity and Proteolytic Stability | 期刊论文 | Kai Chen;Yang Tang;Meng Wu;Xiao-Cui Wan;Yan-Ni Zhang;Xiao-Xu Chen;Fei-Qiang Yu;Zhi-Hui Cui;Jin-Ming Ma;Zhaocai Zhou;Ge-Min Fang |
| 3 | A versatile resin for the generation of thioether-bonded head-to-tail cyclized peptides | 期刊论文 | Xi Tong-Kuai;Zhu Han-Ying;Chen Kai;Yu Fei-Qiang;Zhang Yan-Ni;Fang Ge-Min |
| 4 | Chemical synthesis and racemic crystallization of rat C5a-desArg | 期刊论文 | Zuo Chao;Zhang Baochang;Wu Meng;Bierer Donald;Shi Jing;Fang Ge-Min |
| 5 | Synthesis of Peptide Disulfide-Bond Mimics by Using Fully Orthogonally Protected Diaminodiacids | 期刊论文 | Tao Wang;Jian Fan;Xiao-Xu Chen;Rui Zhao;Yang Xu;Donald Bierer;Lei Liu;Yi-Ming Li;Jing Shi;Ge-Min Fang |
| 6 | Chemical synthesis of thioether-bonded bicyclic peptides using tert-butylthio and Trt-protected cysteines | 期刊论文 | Zhu Han-Ying;Wu Meng;Yu Fei-Qiang;Zhang Yan-Ni;Xi Tong-Kuai;Chen Kai;Fang Ge-Min |
| 7 | Robust synthesis of C-terminal cysteine-containing peptide acids through a peptide hydrazide-based strategy | 期刊论文 | Zuo Chao;Yan Bing-Jia;Zhu Han-Ying;Shi Wei-Wei;Xi Tong-Kuai;Shi Jing;Fang Ge-Min |
| 8 | Non-reducible disulfide bond replacement implies that disulfide exchange is not required for hepcidin–ferroportin interaction | 期刊论文 | Dong-Liang Huang;Jing-Si Bai;Meng Wu;Xia Wang;Bernd Riedl;Elisabeth Pook;Carsten Alt;Marion Erny;Yi-Ming Li;Donald Bierer;Jing Shi;Ge-Min Fang |
| 9 | 一种树脂及其制备方法以及其在制备头尾环肽中的应用 | 专利 | 方葛敏;席痛快;武梦;朱汉英;张燕妮 |
| 10 | Comparison of different strategies towards the chemical synthesis of long-chain scorpion toxin AaH-II | 期刊论文 | Yu-Lei Li;Qian Qu;Yun-Kun Qi;Lei Liu;Ke Wei Wang;Yani Liu;Ge-Min Fang |
| 11 | Delivery of cell membrane impermeable peptides into living cells by using head-to-tail cyclized mitochondria-penetrating peptides | 期刊论文 | Yang Qian-Qian;Zhu Liang-Jing;Xi Tong-Kuai;Zhu Han-Ying;Chen Xiao-Xu;Wu Meng;Sun Chuan;Xu Changzhi;Fang Ge-Min;Meng Xiangming |
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