溶酶体靶向的微环境双光子荧光探针及其在细胞自噬荧光可视化中的应用
21778001
2017
B0701.生物体系分子探针
孟祥明
面上项目
教授
安徽大学
65万元
微环境;实时原位检测;双光子荧光探针;溶酶体靶向;细胞自噬
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | A dual-emission two-photon fluorescent probe for specific-cysteine imaging in lysosomes and in vivo | 期刊论文 | Huang Yinliang;Ren Qifeng;Li Shanqing;Feng Yan;Zhang Wan;Fang Guoshun;Li Linke;Sun Chuan;Wang Xin;Meng Xiangming |
| 2 | A lysosomal polarity-specific two-photon fluorescent probe for visualization of autophagy | 期刊论文 | Yuan Zixiang;Chen Jun;Zhou Qin;Liu Ao;Qiang Zeming;Fang Min;Chen Man;Feng Yan;Yu Haizhu;Yang Xiuli;Meng Xiangming |
| 3 | 一种监测细胞自噬的双光子pH比率计量荧光探针及其制备方法和用途 | 专利 | 孟祥明;候立玲;宁鹏;程浩然;冯燕 |
| 4 | 一种比率型双光子甲醛荧光探针及其制备方法和用途 | 专利 | 孟祥明;倪永兴;郭蒙蒙;朱满洲 |
| 5 | Accurate Monitoring and Multiple Evaluations of Mitophagy by a Versatile Two-Photon Fluorescent Probe | 期刊论文 | Wang Xinru;Chen Qi;Dong Kun;Sun Chuan;Huang Yinliang;Qiang Zeming;Chen Baoqian;Chen Man;Feng Yan;Meng Xiangming |
| 6 | 一种双光子荧光探针及其制备方法和用途 | 专利 | 孟祥明;韦新洁;朱满洲;邵宗龙 |
| 7 | Recent advances in mitochondria- and lysosomes-targeted small-molecule two-photon fluorescent probes | 期刊论文 | Ning Peng;Wang Wenjuan;Chen Man;Feng Yan;Meng Xiangming |
| 8 | A ratiometric two-photon fluorescent probe for selective detection of endogenous formaldehyde via Aza-Cope reaction | 期刊论文 | Yang Hui;Fang Gemin;Guo Mengmeng;Ning Peng;Feng Yan;Yu Haizhu;Meng Xiangming |
| 9 | Delivery of cell membrane impermeable peptides into living cells by using head-to-tail cyclized mitochondria-penetrating peptides | 期刊论文 | Yang Qian-Qian;Zhu Liang-Jing;Xi Tong-Kuai;Zhu Han-Ying;Chen Xiao-Xu;Wu Meng;Sun Chuan;Xu Changzhi;Fang Ge-Min;Meng Xiangming |
| 10 | 一种细胞自噬监测探针及其制备方法和用途 | 专利 | 孟祥明;李龙春;江嘉诚;郭蒙蒙;朱满洲 |
| 11 | Rational design of a ratiometric two-photon fluorescent probe for real-time visualization of apoptosis | 期刊论文 | Huang Yinliang;Zhou Qin;Feng Yan;Zhang Wan;Fang Guoshun;Fang Min;Chen Man;Xu Changzhi;Meng Xiangming |
| 12 | Two-Photon Fluorescent Probe for Monitoring Autophagy via Fluorescence Lifetime Imaging | 期刊论文 | Hou Liling;Ning Peng;Feng Yan;Ding Yaqi;Bai Lei;Li Lin;Yu Haizhu;Meng Xiangming |
| 13 | pH-Independent two-photon fluorescent lysotrackers for real-time monitoring autophagy | 期刊论文 | Wang Wenjuan;Ning Peng;Wang Qi;Zhang Wan;Jiang Jun;Feng Yan;Meng Xiangming |
| 14 | 一种双光子黏度荧光探针及其制备方法和用途 | 专利 | 孟祥明;宁鹏;余升龙;岳平;冯燕;朱满洲 |
| 15 | 一种溶酶体靶向的双光子黏度荧光探针及其制备方法和用途 | 专利 | 孟祥明;宁鹏;倪燕;李晨晨;岳平;冯燕 |
| 16 | Discovery, structure, and chemical synthesis of disulfide-rich peptide toxins and their analogs | 期刊论文 | Fang Ge-Min;Chen Xiao-Xu;Yang Qian-Qian;Zhu Liang-Jing;Li Ning-Ning;Yu Hai-Zhu;Meng Xiang-Ming |
| 17 | Design of a two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorite in mitochondria | 期刊论文 | Linke Li;Xinru Wang;Chuan Sun;Tingting Xu;Zhijian Yang;Zhengsong Zhang;Yan Feng;Min Fang;Man Chen;Xin Wang;Xiangming Meng |
| 18 | Evaluating visually a new apoptosis-induced reagent by a ratiometric two-photon fluorescent pH probe | 期刊论文 | Chen Xiaohua;Chen Qi;Chen Man;Wang Wenjuan;Sun Chuan;Wang Xinru;Ning Peng;Hou Liling;Feng Yan;Meng Xiangming |
| 19 | Real-time visualization of autophagy by monitoring the fluctuation of lysosomal pH with a ratiometric two-photon fluorescent probe | 期刊论文 | Ning Peng;Hou Liling;Feng Yan;Xu Guoyong;Bai Yuyuan;Yu Haizhu;Meng Xiangming |
| 20 | A bright two-photon fluorescent probe for real-time monitoring autophagy in living cells | 期刊论文 | Jiang Chuankun;Li Longchun;Jiang Jiacheng;Hou Lilin;Fang Gemin;Yu Haizhu;Meng Xiangming |
| 21 | A mitochondria-targeted ratiometric two-photon fluorescent probe for detecting intracellular cysteine and homocysteine | 期刊论文 | Yue Ping;Yang Xiuli;Ning Peng;Xi Xinguo;Yu Haizhu;Feng Yan;Shao Rong;Meng Xiangming |
| 22 | 精确结构的金/银团簇的可控合成与构效关系 | 奖励 | 朱满洲;汪恕欣;孟祥明;宋永波;金山 |
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