新颖的靶向多级纳米载体的构建与智能分步控制释药研究

21571002
2015
B0702.生物分子的化学生物学
沈玉华
面上项目
教授
安徽大学
75万元
多级载体;抗肿瘤机制;靶向功能;控制释放;敏感材料
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A pH-Sensitive Composite with Controlled Multistage Drug 期刊论文 Zheng Yang;Wanghua Xu;Mingxiang Ji;Anjian Xie;Yuhua Shen;Manzhou Zhu
2 Litchi-like Fe3O4@Fe-MOF capped with HAp gatekeepers for pH-triggered drug release and anticancer effect 期刊论文 Yang Yongmei;Xia Feng;Yang Ying;Gong Baoyou;Xie Anjian;Shen Yuhua;Zhu Manzhou
3 Reduced Graphene Oxide@Mesoporous Silica-Doxorubicin/Hydroxyapatite Inorganic Nanocomposites: Preparation and pH-Light Dual-Triggered Synergistic Chemo-Photothermal Therapy 期刊论文 Yang Ying;Wang Yunlong;Xu Wanghua;Zhang Xiuzhen;Shang Yong;Xie Anjian;Shen Yuhua
4 pH-Controlled Drug Release of Nitrigen Doped Carbon Dots Delivering Doxorubicine for Synergetic Photo-Thermal Therapy and Chemotherapy 期刊论文 Zheng Yang;Anjian Xie;Yuhua Shen
5 Construction and Synergistic Anticancer Efficacy of Sandwich-like rGO/Fe3O4@mSiO2 Drug Carriers 期刊论文 Yongmei Yang;Mingxiang Ji;Ying Yang;Anjian Xie;Yuhau Shen
6 A novel composite hydrogel initiated by Spinacia oleracea L. extract on Hela cells for localized photodynamic therapy 期刊论文 Pan Le;Li Yanjie;Zhu Lin;Zhang Buchang;Shen Yuhua;Xie Anjian
7 Engineered Targeted Hyaluronic Acid-Glutathione-Stabilized Gold Nanoclusters/Graphene Oxide-5-Fluorouracil as a Smart Theranostic Platform for Stimulus-Controlled Fluorescence Imaging-Assisted Synergetic Chemo/Phototherapy 期刊论文 Yang Ying;Wang Shuxin;Wang Chen;Tian Chen;Shen Yuhua;Zhu Manzhou
8 A GO@PLA@ HA Composite Microcapsule: Its Preparation and Multistage and Controlled Drug Release 期刊论文 Guo Hailing;Wang Yunlong;Huang Yiping;Huang Fangzhi;Li Shikuo;Shen Yuhua;Zhu Manzhou;Xie Anjian
9 Switching the subcellular organelle targeting of atomically precise gold nanoclusters by modifying the capping ligand 期刊论文 Yang Ying;Wang Shuxin;Chen Shuang;Shen Yuhua;Zhu Manzhou
10 Biomimetic Synthesis of Hydroxyapitite Nanocrystals Controlled by Chinese Yam 会议论文 Mingxiang Ji;Anjian Xie;Yuhua Shen
11 RGO/AuNR/HA-5FU nanocomposite with multi-stage release behavior and efficient antitumor activity for synergistic therapy 期刊论文 Yang Ying;Wang Yunlong;Zhu Manzhou;Chen Yan;Xiao Yazhong;Shen Yuhua;Xie Anjian
12 A pH-induced charge convertible nanocomposite as novel targeted phototherapy agent and gene carrier 期刊论文 Yang Zheng;Hou Bo;Yang Ying;Jiang Lanxuan;Xie Anjian;Shen Yuhua;Zhu Manzhou
13 Effective photodynamic therapy of polymer hydrogel on tumor cells prepared using methylene blue sensitized mesoporous titania nanocrystal 期刊论文 Chang Guanru;Zhang Hui;Li Shikuo;Huang Fangzhi;Shen Yuhua;Xie Anjian
14 A novel porous aspirin-loaded (GO/CTS-HA)nnanocomposite films:Synthesis and multifunction for bone tissue engineeringMingxiang 期刊论文 Mingxaing Ji;Han Li;Hailin Guo;Anjian Xie;Shaohua Wang;Fangzhi Huang;Shikuo Li;Yuhua Shen;Jiacai He
15 Multifunctional Reduced Graphene Oxide Hydrogel as Drug Carrier for Localized and Synergic Photothermal/Photodynamics/Chemo Therapy 期刊论文 Chang Guanru;Li Shikuo;Huang Fangzhi;Zhang Xiuzhen;Shen Yuhua;Xie Anjian
16 Photosensitive multifunctional poly(vinyl alcohol) micelles for enhanced antitumor effect 期刊论文 Yu Qingbo;Xie Anjian;Huang Fangzhi;Li Shikuo;Xiao Yazhong;Shen Yuhua
17 Graphene oxide and creatine phosphate disodium dual template-directed synthesis of GO/hydroxyapatite and its application in drug delivery 期刊论文 Yao Chengli;Zhu Jinmiao;Xie Anjian;Shen Yuhua;Li Hongying;Zheng Bin;Wei Yanxin
18 Fe3O4@MnO2@ PPy nanocomposites overcome hypoxia: magnetic-targeting-assisted controlled chemotherapy and enhanced photodynamic/photothermal therapy 期刊论文 Yang Ying;Wang Chen;Tian Chen;Guo Hailing;Shen Yuhua;Zhu Manzhou
19 Improved fluorescence imaging and synergistic anticancer phototherapy of hydrosoluble gold nanoclusters assisted by a novel two-level mesoporous canal structured silica nanocarrier 期刊论文 Yang Ying;Wang Shuxin;Xu Changzhi;Xie Anjian;Shen Yuhua;Zhu Manzhou
20 A novel 5-FU/rGO/Bce hybrid hydrogel shell on a tumor cell: one-step synthesis and synergistic chemo/photo-thermal/photodynamic effect 期刊论文 Yang Ying;Zhu Lin;Xia Feng;Gong Baoyou;Xie Anjian;Li Shikuo;Huang Fangzhi;Wang Shaohua;Shen Yuhua;Weaver David T
21 4-in-1 phototheranostics: PDA@CoPA-LA nanocomposite for photothermal imaging/photothermal/in-situ O2 generation/photodynamic combination 期刊论文 Zheng Yang;Xinyu Liu;Xueyan Wang;Pengcheng Wang;Shanshan Ruan;Anjian Xie;Yuhua Shen;Manzhou Zhu
22 Construction and synergistic anticancer efficacy of magnetic targeting cabbage-like Fe3O4@MoS2@ZnO drug carriers 期刊论文 Yang Yongmei;Gong Baoyou;Yang Ying;Xie Anjian;Shen Yhua;Zhu Manzhou
23 Methylene blue/titania nanoparticles-phototriggered polymer Hydrogel formation on tumor cells for localized photodynamic antitumor 会议论文 Yuhua Shen;Anjian Xie
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