典型药物污染物卡马西平及其代谢产物对斑马鱼的神经行为毒性和作用机制研究

41907222
2019
D0708.生态毒理学
陈辉辉
青年科学基金项目
副研究员
中国科学院南京地理与湖泊研究所
25万元
神经行为毒性;有害结局路径;药物活性化合物;基因组学;毒性作用机制
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Characterization of the GABAergic system in Asian clam Corbicula fluminea: Phylogenetic analysis, tissue distribution, and response to the aquatic contaminant carbamazepine 期刊论文 Huihui Chen;Xiaohong Gu;Qingfei Zeng;Zhigang Mao;Martyniuk J. Christopher
2 Co-occurrence of multiple cyanotoxins and taste-and-odor compounds in the large eutrophic Lake Taihu, China: Dynamics, driving factors, and challenges for risk assessment 期刊论文 Hongmin Li;Xiaohong Gu;Huihui Chen;Zhigang Mao;Ruijie Shen;Qingfei Zeng;You Ge
3 超高效液相色谱-串联质谱法同时测定环境水体中15种精神类药物 期刊论文 金苗;杨慧婷;陈辉辉;沈幸;王钰洋;沈睿杰
4 Occurrence and Bioaccumulation of Psychotropic Pharmaceuticals and Their Metabolites in Water and Fish in a Shallow Lake in China: Implications for Ecological and Human Health Risks 期刊论文 Yuxin Weng;Huiting Yang;Huihui Chen;Yan Xu;Xiaohong Gu;Zhonghua Zhao;Miao Jin;Zhigang Mao;Qingfei Zeng;Jinmiao Zha;Christopher J. Martyniuk
5 Molecular and behavioral responses of zebrafish embryos/larvae after sertraline exposure 期刊论文 Huiting Yang;Xuefang Liang;Yanyan Zhao;Xiaohong Zhao;Zhigang Mao;Qingfei Zeng;Huihui Chen;Christopher J. Martyniuk
6 Environmentally relevant concentrations of sertraline disrupts behavior and the brain and liver transcriptome of juvenile yellow catfish (Tachysurus fulvidraco): Implications for the feeding and growth axis 期刊论文 Huihui Chen;Xuefang Liang;Xiaohong Gu;Qingfei Zeng;Zhigang Mao;Martyniuk J. Christopher
7 Transcriptome profiling reveals toxicity mechanisms following sertraline exposure in the brain of juvenile zebrafish (Danio rerio) 期刊论文 Huiting Yang;Xiaohong Gu;Huihui Chen;Qingfei Zeng;Zhigang Mao;Miao Jin;Hongmin Li;You Ge;Jinmiao Zha;Christopher J. Martyniuk
8 江苏高宝邵伯湖表层水体典型精神类药物及其代谢产物的污染水平、分布特征及风险评估 期刊论文 翁郁馨;杨慧婷;陈辉辉;许妍;谷孝鸿;金苗;毛志刚;曾庆飞
9 Development and molecular investigation into the effects of carbamazepine exposure in the zebrafish (Danio rerio) 期刊论文 Huihui Chen;Huiting Yang;Yanyan Zhao;Xiaohong Gu;Christopher J Martyniuk
10 Comparative toxicological effects of planktonic Microcystis and benthic Oscillatoria on zebrafish embryonic development: Implications for cyanobacteria risk assessment 期刊论文 Hongmin Li;Xiaohong Gu;Huihui Chen;Zhigang Mao;Qingfei Zeng;Huiting Yang;Kecong Kan
11 环境相关浓度的卡马西平对斑马鱼幼鱼抗氧化系统和神经递质系统的影响 期刊论文 杨慧婷;谷孝鸿;陈辉辉;曾庆飞;毛志刚;李红敏;葛优;查金苗
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