器官芯片技术仿生构建肝-胰组织互作模型与药物评价新体系、新方法

31971373
2019
C2104.共性生物技术
秦建华
面上项目
研究员
中国科学院大连化学物理研究所
60万元
多器官芯片;器官芯片;微生理系统;药物筛选;器官间相互作用
2020-01-01到2023-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Controllable Fabrication of Composite Core-Shell Capsules at a Macroscale as Organoid Biocarriers 期刊论文 He Fan;Tao Tingting;Liu Haitao;Wang Yaqing;Cui Kangli;Guo Yaqiong;Qin Jianhua
2 Human Organoids and Organs‐on‐Chips for Addressing COVID‐19 Challenges 期刊论文 Yaqing Wang;Peng Wang;Jianhua Qin
3 A Transwell-Based Vascularized Model to Investigate the Effect of Interstitial Flow on Vasculogenesis 期刊论文 Pengwei Deng;Mengqian Zhao;Xu Zhang;Jianhua Qin
4 Microfluidic Organs-on-a-Chip for Modeling Human Infectious Diseases 期刊论文 Yaqing Wang;Peng Wang;Jianhua Qin
5 Blood–brain barrier injury and neuroinflammation induced by SARS-CoV-2 in a lung–brain microphysiological system 期刊论文 Peng Wang;Lin Jin;Min Zhang;Yunsong Wu;Zilei Duan;Yaqiong Guo;Chaoming Wang;Yingqi Guo;Wenwen Chen;Zhiyi Liao;Yaqing Wang;Ren Lai;Luke P. Lee;Jianhua Qin
6 一种基于微流控技术的体外无泵组织培养芯片 专利 秦建华;郭雅琼
7 一种通用型器官芯片灌流装置 专利 秦建华;邓鹏伟
8 一种基于层流效应的微流控芯片谷胱甘肽局部亲水修饰法 专利 秦建华;刘海涛
9 一种基于三维类肝芯片的非酒精性脂肪肝体外模型建立方法 专利 秦建华;王亚清;王慧
10 类器官芯片 期刊论文 王亚清;陶婷婷;秦建华
11 A Droplet Microfluidic System to Fabricate Hybrid Capsules Enabling Stem Cell Organoid Engineering 期刊论文 Liu Haitao;Wang Yaqing;Wang Hui;Zhao Mengqian;Tao Tingting;Zhang Xu;Qin Jianhua
12 一种心/肝/胎盘/脑/胰岛多器官芯片 专利 秦建华;邓鹏伟
13 One‐Step Generation of Porous GelMA Microgels by Droplet‐Based Chaotic Advection Effect 期刊论文 Zhongqiao Gan;Haitao Liu;Yaqing Wang;Tingting Tao;Mengqian Zhao;Jianhua Qin
14 HiPSC-derived multi-organoids-on-chip system for safety assessment of antidepressant drugs 期刊论文 Yin Fangchao;Zhang Xu;Wang Li;Wang Yaqing;Zhu Yujuan;Li Zhongyu;Tao Tingting;Chen Wenwen;Yu Hao;Qin Jianhua
15 One-Step Generation of Aqueous-Droplet-Filled Hydrogel Fibers as Organoid Carriers Using an All-in-Water Microfluidic System 期刊论文 Wang Hui;Liu Haitao;Zhang Xu;Wang Yaqing;Zhao Mengqian;Chen Wenwen;Qin Jianhua
16 一种用于三维细胞培养的模块化插件 专利 秦建华;邓鹏伟
17 Recent advances in defined hydrogels in organoid research 期刊论文 Zhongqiao Gan;Xinyuan Qin;Haitao Liu;Jiayue Liu;Jianhua Qin
18 Microengineered Multi‐Organoid System from hiPSCs to Recapitulate Human Liver‐Islet Axis in Normal and Type 2 Diabetes (Adv. Sci. 5/2022) 期刊论文 Tingting Tao;Pengwei Deng;Yaqing Wang;Xu Zhang;Yaqiong Guo;Wenwen Chen;Jianhua Qin
19 One-step synthesis of composite hydrogel capsules to support liver organoid generation from hiPSCs 期刊论文 Wang Yaqing;Liu Haitao;Zhang Min;Wang Hui;Chen Wenwen;Qin Jianhua
20 Advances in human organoids-on-chips in biomedical research 期刊论文 Yaqing Wang;Jianhua Qin
21 A flexible microfluidic strategy to generate grooved microfibers for guiding cell alignment 期刊论文 Zhao Mengqian;Liu Haitao;Zhang Xu;Wang Hui;Tao Tingting;Qin Jianhua
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