内源性类固醇激素高覆盖分析策略研究及其应用
21874130
2018
B0401.分离与分析
胡春秀
面上项目
副研究员
中国科学院大连化学物理研究所
65万元
结构鉴定;代谢组学;类固醇激素;卵巢癌;高覆盖分析
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Effect of roxadustat on serum metabolome and lipidome in patients with end-stage renal disease and erythropoiesis-stimulating agent resistance | 期刊论文 | Wang Lichao;Wu Yulin;Li Yongjiang;You Lianlian;Liu Xinyu;Wang Zhihong;Xiao Jia;Zhang Shuang;Xu Tianrun;Wang Xiaolin;Li Qi;Hu Chunxiu;Xu Guowang;Liu Shuxin |
| 2 | Strategy for Nontargeted Metabolomic Annotation and Quantitation Using a High-Resolution Spectral-Stitching Nanoelectrospray Direct-Infusion Mass Spectrometry with Data-Independent Acquisition | 期刊论文 | Wang Lichao;Lv Wangjie;Sun Xiaoshan;Zheng Fujian;Xu Tianrun;Liu Xinyu;Li Hang;Lu Xin;Peng Xiaojun;Hu Chunxiu;Xu Guowang |
| 3 | Parallel derivatization strategy coupled with liquid chromatography-mass spectrometry for broad coverage of steroid hormones | 期刊论文 | Qin Qian;Feng Disheng;Hu Chunxiu;Wang Bohong;Chang Mengmeng;Liu Xinyu;Yin Peiyuan;Shi Xianzhe;Xu Guowang |
| 4 | Rapid lipidomic profiling based on ultra-high performance liquid chromatography-mass spectrometry and its application in diabetic retinopathy | 期刊论文 | Xuan Qiuhui;Zheng Fujian;Yu Di;Ouyang Yang;Zhao Xinjie;Hu Chunxiu;Xu Guowang |
| 5 | 一种用于细胞实验的多维度精调节分析平台 | 专利 | 李杭;许国旺;石先哲;丰迪生;胡春秀 |
| 6 | 一种基于直接进样质谱的定性和定量分析方法 | 专利 | 许国旺;王利超;胡春秀;石先哲;刘心昱;路鑫;秦望舒 |
| 7 | 一种基于双衍生处理分析甾体激素的检测方法 | 专利 | 石先哲;秦倩;王博弘;许国旺 |
| 8 | 基于液相色谱-质谱联用的高覆盖代谢组学方法开发及应用 | 奖励 | 许国旺;赵欣捷;石先哲;刘心昱;胡春秀;周丽娜;赵春霞;路鑫;尹沛源;许志良 |
| 9 | 基于阵列孔板珠打研磨的细胞前处理装置及方法 | 专利 | 许国旺;李杭;贾震;石先哲;赵金慧;胡春秀 |
| 10 | 一种单细胞在线化学衍生质谱分析装置 | 专利 | 许国旺;李杭;徐天润;胡春秀;贾震;周丽娜 |
| 11 | Recent advances in analytical strategies for mass spectrometry-based lipidomics | 期刊论文 | Xu Tianrun;Hu Chunxiu;Xuan Qiuhui;Xu Guowang |
| 12 | 一种少量细胞脂质组学分析方法 | 专利 | 许国旺;徐天润;胡春秀;李杭;丰迪生;秦望舒 |
| 13 | 一种血清代谢标志物的用途及检测试剂盒 | 专利 | 许国旺;轩秋慧;欧阳瑒;王砚凤;赵欣捷;胡春秀 |
| 14 | 联合标志物及在诊断心房颤动中应用及诊断试剂或试剂盒 | 专利 | 许国旺;张雨晴;赵欣捷;刘心昱;吕王洁;胡春秀;徐天润 |
| 15 | Human Prostate Cancer Is Characterized by an Increase in Urea Cycle Metabolites | 期刊论文 | Franko Andras;Shao Yaping;Heni Martin;Hennenlotter Joerg;Hoene Miriam;Hu Chunxiu;Liu Xinyu;Zhao Xinjie;Wang Qingqing;Birkenfeld Andreas L.;Todenhoefer Tilman;Stenzl Arnulf;Peter Andreas;Haering Hans-Ulrich;Lehmann Rainer;Xu Guowang;Lutz Stefan Z. |
| 16 | Linking bioenergetic function of mitochondriato tissue-specific molecular fingerprints | 期刊论文 | Kappler Lisa;Hoene Miriam;Hu Chunxiu;von Toerne Christine;Li Jia;Bleher Daniel;Hoffmann Christoph;Böhm Anja;Kollipara Laxmikanth;Zischka Hans;Königsrainer Alfred;Häring Hans-Ulrich;Peter Andreas;Xu Guowang;Sickmann Albert;M.Hauck Stefanie;Weigert Cora;Lehmann Rainer |
| 17 | Protein profiling analysis based on matrix-assisted laser desorption/ionization-Fourier transform ion cyclotron resonance mass spectrometry and its application in typing Streptomyces isolates | 期刊论文 | Sun Xiaoshan;Wu Peichun;Zhao Chunxia;Zheng Fujian;Hu Chunxiu;Lu Xin;Xu Guowang |
| 18 | Exercise prevents fatty liver by modifying the compensatory response of mitochondrial metabolism to excess substrate availability | 期刊论文 | Hoene Miriam;Kappler Lisa;Kollipara Laxmikanth;Hu Chunxiu;Irmler Martin;Bleher Daniel;Hoffmann Christoph;Beckers Johannes;de Angelis Martin Hrabe;Haring Hans-Ulrich;Birkenfeld Andreas L.;Peter Andreas;Sickmann Albert;Xu Guowang;Lehmann Rainer;Weigert Cora |
| 19 | 一种用于单细胞取样与喷针快速更换的操作仪 | 专利 | 许国旺;李杭;徐天润;胡春秀 |
| 20 | 基于石英阵列微孔板的细胞破壁装置 | 专利 | 许国旺;李杭;徐天润;胡春秀;窦鹏;刘心昱 |
| 21 | 联合型代谢标志物的试剂在制备用于诊断食管上皮非典型增生疾病的试剂盒中的用途 | 专利 | 陆欣;李艳丽;路鑫;胡春秀;王砚凤;许国旺 |
| 22 | 一种用于快速鉴别质谱样本聚乙二醇污染的方法 | 专利 | 陆欣;许国旺;胡春秀;张秀琼;由蕾;孙晓珊 |
| 23 | Untargeted Lipidomics Reveals Specific Lipid Abnormalities in Nonfunctioning Human Pituitary Adenomas | 期刊论文 | Hu Chunxiu;Zhou Yang;Feng Jie;Zhou Shiyu;Li Chuzhong;Zhao Sida;Shen Yutao;Hong Lichuan;Xuan Quhui;Liu Xinyu;Li Qi;Wang Xiaolin;Zhang Yazhuo;Xu Guowang |
| 24 | Muscle-Liver Substrate Fluxes in Exercising Humans and Potential Effects on Hepatic Metabolism | 期刊论文 | Hu Chunxiu;Hoene Miriam;Plomgaard Peter;Hansen Jakob S.;Zhao Xinjie;Li Jia;Wang Xiaolin;Clemmesen Jens O.;Secher Niels H.;Haering Hans U.;Lehmann Rainer;Xu Guowang;Weigert Cora |
| 25 | Serum lipidomics profiles reveal potential lipid markers for prediabetes and type 2 diabetes in patients from multiple communities | 期刊论文 | Xuan Qiuhui;Hu Chunxiu;Zhang Yinan;Wang Qingqing;Zhao Xinjie;Liu Xinyu;Wang Congrong;Jia Weiping;Xu Guowang |
| 26 | 一种纳升电喷雾离子化的质谱仪接口装置 | 专利 | 李杭;许国旺;石先哲;丰迪生;胡春秀 |
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