离子液体在质膜蛋白质规模化分离分析中的作用机制及应用研究
21834006
2018
B0401.分离与分析
张丽华
重点项目
研究员
中国科学院大连化学物理研究所
315万元
样品处理;离子液体;机理研究;蛋白质组;质膜蛋白质和复合体
2019-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Metal organic layers enabled cell surface engineering coupling biomembrane fusion for dynamic membrane proteome profiling | 期刊论文 | Qianqian Jiang;He Wang;Zichun Qiao;Yutong Hou;Zhigang Sui;Baofeng Zhao;Zhen Liang;Bo Jiang;Yukui Zhang;Lihua Zhang |
| 2 | 膜蛋白质复合物提取方法研究进展 | 期刊论文 | 褚宏伟;郑诗颖;赵群;赵宝锋;梁振;张丽华;张玉奎 |
| 3 | Tracking the Micro-Heterogeneity and Hydrogen-Bonding Interactions in Hydroxyl-Functionalized Ionic Liquid Solutions: A Combined Experimental and Computational Study | 期刊论文 | Yaqing Zhang;Xin Tan;Weilu Ding;Yanlei Wang;Hongyan He;Zhiwu Yu |
| 4 | 肝癌药物的辅助治疗药物及应用和治疗肝癌药物混合物 | 专利 | 张丽华;张堃;王子璇;马宝福;潘慧;赵宝锋;梁振;杨开广;张玉奎 |
| 5 | 基于离子液体的蛋白质组样品制备新方法 | 期刊论文 | 郑诗颖;褚宏伟;赵群;赵宝锋;张丽华;张玉奎 |
| 6 | Segmented MS/MS acquisition of a1 ion-based strategy for in-depth proteome quantitation | 期刊论文 | Zhiting Wang;Chao Liu;Songduo Wang;Xinhang Hou;Pengyun Cong;Xiao Li;Zhen Liang;Jianhui Liu;Lihua Zhang;Yukui Zhang |
| 7 | 一种活细胞膜蛋白质靶向光交联剂及其制备和应用 | 专利 | 张丽华;刘祎;赵群;毛永爆;杨开广;梁振;张玉奎 |
| 8 | Proteomic Analysis Reveals that EPHX1 Contributes to 5-Fluorouracil Resistance in a Human Hepatocellular Carcinoma Cell Line | 期刊论文 | Rui Sun;Chengyong Dong;Rui Li;Hongwei Chu;Jianhui Liu;Dingjun Hao;Lihua Zhang;Baofeng Zhao;Liming Wang;Yukui Zhang |
| 9 | Pushpin-like nanozyme for plasmon-enhanced tumor targeted therapy | 期刊论文 | Baofu Ma;Kun Zhang;Zhen Sun;Hui Pan;Kaiguang Yang;Bo Jiang;Baofeng Zhao;Zhen Liang;Yukui Zhang;Lihua Zhang |
| 10 | Quantitative proteomics identifies FOLR1 to drive sorafenib resistance via activating autophagy in hepatocellular carcinoma cells | 期刊论文 | Hongwei Chu;Changqing Wu;Qun Zhao;Rui Sun;Kuo Yang;Baofeng Zhao;Yang Liu;Zhen Liang;Shijun Zhong;Lihua Zhang;Yukui Zhang |
| 11 | Investigating the property and strength of intermolecular interaction in saturated and unsaturated cyclic cations constructed ionic liquids | 期刊论文 | Tao Zhang;Wei-lu Ding;Yaqin Zhang;Kailun Bi;Yumiao Lu;Lin Ji;Hongyan He |
| 12 | Enhancing Top-Down Characterization of Membrane Proteoforms with C8-Functional Amine-Bridged Hybrid Monoliths | 期刊论文 | Yue Sun;Yu Liang;Chao Wang;Baofeng Zhao;Zhen Liang;Xiaodan Zhang;Yukui Zhang;Lihua Zhang |
| 13 | 一种用于生物样本的高能量紫外交联仪 | 专利 | 张丽华;戴忠鹏;赵群;陈宇文;杨开广;张玉奎 |
| 14 | FOLR1抑制剂的应用和治疗肝癌药物混合物 | 专利 | 张丽华;褚宏伟;赵宝锋;马宝福;王子璇;杨开广;梁振;张玉奎 |
| 15 | Deep coverage proteome analysis of hair shaft for forensic individual identification | 期刊论文 | Jialei Wu;Jianhui Liu;Anquan Ji;Dongsheng Ding;Guiqiang Wang;Yao Liu;Lihua Zhang;Lei Fang;Jian Ye |
| 16 | 一种多功能交联剂及其制备方法和应用 | 专利 | 张丽华;高航;赵群;赵丽丽;张玉奎 |
| 17 | Interaction and Mechanism between Imidazolium Ionic Liquids and the Zwitterionic Amino Acid Tyr: a DFT Study | 期刊论文 | Zhiwei Wu;Weilu Ding;Yaqin Zhang;Yanlei Wang;Hongyan He |
| 18 | AKR1C3-dependent lipid droplet formation confers hepatocellular carcinoma cell adaptability to targeted therapy | 期刊论文 | Changqing Wu;Chaoliu Dai;Xinyu Li;Mingju Sun;Hongwei Chu;Qiuhui Xuan;Yalei Yin;Chengnan Fang;Fan Yang;Zhonghao Jiang;Qing Lv;Keqing He;Yiying Qu;Baofeng Zhao;Ke Cai;Shujun Zhang;Ran Sun;Guowang Xu;Lihua Zhang;Siyu Sun;Yang Liu |
| 19 | Insights into Ionic Liquids: From ZBonds to Quasi-Liquids | 期刊论文 | Yanlei Wang;Hongyan He;Chenlu Wang;Yumiao Lu;Kun Dong;Feng Huo;Suojiang Zhang |
| 20 | Molecular Dynamics Simulation-assisted Ionic Liquid Screening for Deep Coverage Proteome Analysis | 期刊论文 | Fei Fang;Qun Zhao;Huiying Chu;Mingwei Liu;Baofeng Zhao;Zhen Liang;Lihua Zhang;Guohui Li;Liming Wang;Jun Qin;Yukui Zhang |
| 21 | Abnormal Enhanced Free Ions of Ionic Liquids Confined in Carbon Nanochannels | 期刊论文 | Mi Wang;Yanlei Wang;Chenlu Wang;Zhongdong Gan;Feng Huo;Hongyan He;Suojiang Zhang |
| 22 | 一种基于胆固醇膜锚定基团的细胞表面蛋白靶向富集方法 | 专利 | 张丽华;蒋倩倩;江波;王鹤;赵宝锋;杨开广;张玉奎 |
| 23 | 一步富集型细胞表面靶向交联剂及制备和应用 | 专利 | 张丽华;刘祎;赵群;吴慈;杨开广;梁振;张玉奎 |
| 24 | Ionic liquid-trimetallic electrocatalytic system for C–O bond cleavage in lignin model compounds and lignin under ambient conditions | 期刊论文 | Guangyong Liu;Yumiao Lu;JunFeng Lu;Yanlei Wang;Shijing Liang;Hongyan He;Lilong Jiang |
| 25 | 一种基于吡咯烷基离子液体提取的膜蛋白质复合体分析方法 | 专利 | 张丽华;郑诗颖;赵群;赵宝锋;杨开广;张玉奎 |
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