基于非天然糖代谢标记的分泌蛋白质糖基化精细分析新方法研究

21775146
2017
B0401.分离与分析
秦洪强
面上项目
研究员
中国科学院大连化学物理研究所
65万元
位点特异性糖型;非天然糖代谢标记;分泌蛋白质;肿瘤耐药;糖基化位点占有率
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Automated Intact Glycopeptide Enrichment Method Facilitating Highly Reproducible Analysis of Serum Site-Specific N-Glycoproteome 期刊论文 Liu Luyao;Zhu Bin;Fang Zheng;Zhang Na;Qin Hongqiang;Guo Zhimou;Liang Xinmiao;Yao Zhenzhen;Ye Mingliang
2 Glycoproteomics Analysis Reveals Differential Expression of Site-Specific Glycosylation in Human Milk Whey during Lactation 期刊论文 Wang Zhongyu;Zhang Na;Wang Wendan;Li Yitong;Szeto Ignatius M.;Qin Hongqiang;Jin Yan;Ye Mingliang
3 一种基于化学酶促的人血清O糖基化鉴定方法 专利 叶明亮;由昕;秦洪强
4 Profiling of Endogenously Intact N-Linked and O-Linked Glycopeptides from Human Serum Using an Integrated Platform 期刊论文 Wang Shuyue;Qin Hongqiang;Mao Jiawei;Fang Zheng;Chen Yao;Zhang Xiaolei;Hu Lianghai;Ye Mingliang
5 Highly Efficient Identification of O-GalNAc Glycosylation by an Acid-Assisted Glycoform Simplification Approach 期刊论文 Xin You;Hongqiang Qin;Jiawei Mao;Yu Tian;Mingming Dong;Zhimou Guo;Xinmiao Liang;Liming Wang;Yan Jin;Mingliang Ye
6 一种功能化修饰纳米介孔材料的制备方法和应用 专利 邹汉法;秦洪强;叶明亮;欧俊杰
7 Highly Efficient Enrichment of O-GlcNAc Glycopeptides Based on Chemical Oxidation and Reversible Hydrazide Chemistry 期刊论文 Chen Yao;Qin Hongqiang;Yue Xuyang;Zhou Jiahua;Liu Luyao;Nie Yongzhan;Ye Mingliang
8 一种基于化学反应简化的O-G alNAc糖基化肽段鉴定方法 专利 叶明亮;由昕;秦洪强
9 Highly Efficient Enrichment of O-GalNAc Glycopeptides by Using Immobilized Metal Ion Affinity Chromatography 期刊论文 Yue Xuyang;Qin Hongqiang;Chen Yao;Fang Zheng;Liu Luyao;Zhu He;Liu Xiaoyan;Zhou Jiahua;Tian Kailu;Qiao Xiaoqiang;Ye Mingliang
10 Chemoenzymatic Approach for the Proteomics Analysis of Mucin-Type Core-1 O-Glycosylation in Human Serum 期刊论文 Xin You;Yating Yao;Jiawei Mao;Hongqiang Qin;Xinmiao Liang;Liming Wang;Mingliang Ye
11 Highly Efficient Analysis of Glycoprotein Sialylation in Human Serum by Simultaneous Quantification of Glycosites and Site-Specific Glycoforms 期刊论文 Qin Hongqiang;Dong Xuefang;Mao Jiawei;Chen Yao;Dong Mingming;Wang Liming;Guo Zhimou;Liang Xinmiao;Ye Mingliang
12 Mirror-Cutting-Based Digestion Strategy Enables the In-Depth and Accuracy Characterization of N-Linked Protein Glycosylation 期刊论文 Chen Yao;Fang Zheng;Zhou Jiahua;Qin Hongqiang;Ye Mingliang
13 Multi-histidine functionalized material for the specific enrichment of sialylated glycopeptides 期刊论文 Wang Shuyue;Qin Hongqiang;Dong Jing;Hu Lianghai;Ye Mingliang
14 Proteomics analysis of site-specific glycoforms by a virtual multistage mass spectrometry method 期刊论文 Qin Hongqiang;Chen Yao;Mao Jiawei;Cheng Kai;Sun Deguang;Dong Mingming;Wang Lu;Wang Liming;Ye Mingliang
15 一种高通量富集和鉴定内源性N/O-连接糖肽的方法 专利 叶明亮;王舒越;秦洪强;陈尧;王璐
16 一种基于拟多级谱策略的N-连接糖肽鉴定与定量分析方法 专利 叶明亮;秦洪强;陈尧;王璐
17 A New Searching Strategy for the Identification of O-Linked Glycopeptides 期刊论文 Mao Jiawei;You Xin;Qin Hongqiang;Wang Chenye;Wang Liming;Ye Mingliang
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