猪繁殖与呼吸综合征病毒ORF1b影响其致病性的分子机制

31330077
2013
C1802.兽医病毒学
杨汉春
重点项目
教授
中国农业大学
297万元
致病性;分子机制;致病机制;开放阅读框1b;猪繁殖与呼吸综合征病毒
2014-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 The DEAD-box RNA helicase 5 positively regulates the replication of porcine reproductive and respiratory syndrome virus by interacting with viral Nsp9 in vitro 期刊论文 Zhao Shuangcheng;Ge Xinna;Wang Xiaolong;Liu Aijing;Guo Xin;Zhou Lei;Yu Kangzhen;Yang Hanchun
2 The interaction of nonstructural protein 9 with retinoblastoma protein benefits the replication of genotype 2 porcine reproductive and respiratory syndrome virus in vitro 期刊论文 Dong Jianguo;Zhang Ning;Ge Xinna;Zhou Lei;Guo Xin;Yang Hanchun
3 Nsp9 and Nsp10 Contribute to the Fatal Virulence of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Emerging in China 期刊论文 Li Yan;Zhou Lei;Zhang Jialong;Ge Xinna;Zhou Rong;Zheng Huaguo;Geng Gang;Guo Xin;Yang Hanchun
4 Both Nsp1 beta and Nsp11 are responsible for differential TNF-alpha production induced by porcine reproductive and respiratory syndrome virus strains with different pathogenicity in vitro 期刊论文 He Qing;Li Yan;Zhou Lei;Ge Xinna;Guo Xin;Yang Hanchun
5 Nonstructural protein 9 residues 586 and 592 are critical sites in determining the replication efficiency and fatal virulence of the Chinese highly pathogenic porcine reproductive and respiratory syndrome virus 期刊论文 Lei Xu;Lei Zhou;Weifeng Sun;Pingping Zhang;Xinna Ge;Xin Guo;Jun Han;Hanchun Yang
6 Interleukin-2 enhancer binding factor 2 interacts with the nsp9 or nsp2 of porcine reproductive and respiratory syndrome virus and exerts negatively regulatory effect on the viral replication 期刊论文 Wen Xuexia;Bian Ting;Zhang Zhibang;Zhou Lei;Ge Xinna;Han Jun;Guo Xin;Yang Hanchun;Yu Kangzhen
7 Highly pathogenic porcine reproductive and respiratory syndrome virus infection results in acute lung injury of the infected pigs 期刊论文 Han Deping;Hu Yanxin;Li Limin;Tian Haiyan;Chen Zhi;Wang Lin;Ma Haiyan;Yang Hanchun;Teng Kedao
8 猪繁殖与呼吸综合征 专著 杨汉春;田克恭;肖少波;周磊
9 Cellular DEAD-box RNA helicase 18 (DDX18) Promotes the PRRSV Replication via Interaction with Virus nsp2 and nsp10 期刊论文 Jin Huan;Zhou Lei;Ge Xinna;Zhang Han;Zhang Ruimin;Wang Cong;Wang Li;Zhang Zhibang;Yang Hanchun;Guo Xin
10 Porcine reproductive and respiratory syndrome virus counteracts the porcine intrinsic virus restriction factors-IFITM1 and Tetherin in MARC-145 cells 期刊论文 Wang Xiaolong;Li Congcong;Zhou Lei;Zhang Ning;Wang Xingchen;Ge Xinna;Guo Xin;Yang Hanchun
11 一种抑制猪繁殖与呼吸综合征病毒细胞内复制的药物 专利 杨汉春
12 Interactome Profile of the Host Cellular Proteins and the Nonstructural Protein 2 of Porcine Reproductive and Respiratory Syndrome Virus 期刊论文 Wang Li;Zhou Lei;Zhang Han;Li Yan;Ge Xinna;Guo Xin;Yu Kangzhen;Yang Hanchun
13 Induction of Apoptosis by the Nonstructural Protein 4 and 10 of Porcine Reproductive and Respiratory Syndrome Virus 期刊论文 Yuan Shuaizhen;Zhang Ning;Xu Lei;Zhou Lei;Ge Xinna;Guo Xin;Yang Hanchun
14 The amino acid at residue 155 in nonstructural protein 4 of porcine reproductive and respiratory syndrome virus contributes to its inhibitory effect for interferon-beta transcription in vitro 期刊论文 Chen Zhi;Li Mou;He Qing;Du Jige;Zhou Lei;Ge Xinna;Guo Xin;Yang Hanchun
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