雌激素受体α和β在水飞蓟宾对抗中波紫外线皮肤损伤中的作用研究
81703528
2017
H3504.抗炎与免疫药物药理
刘伟伟
青年科学基金项目
副教授
沈阳药科大学
20万元
表皮细胞;雌激素受体;中波紫外线;水飞蓟宾;真皮细胞
2018-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Silibinin-induced mitochondria fission leads to mitophagy, which attenuates silibinin-induced apoptosis in MCF-7 and MDA-MB-231 cells | 期刊论文 | Si Lingling;Fu Jianing;Liu Weiwei;Hayashi Toshihiko;Mizuno Kazunori;Hattori Shunji;Fujisaki Hitomi;Onodera Satoshi;Ikejima Takashi |
| 2 | Silibinin-induced apoptosis of breast cancer cells involves mitochondrial impairment | 期刊论文 | Si Lingling;Liu Weiwei;Hayashi Toshihiko;Ji Yachao;Fu Jianing;Nie Yuheng;Mizuno Kazunori;Hattori Shunji;Onodera Satoshi;Ikejima Takashi |
| 3 | DNA damage-triggered activation of cGAS-STING pathway induces apoptosis in human keratinocyte HaCaT cells | 期刊论文 | Li Can;Liu Weiwei;Wang Fang;Hayashi Toshihiko;Mizuno Kazunori;Hattori Shunji;Fujisaki Hitomi;Ikejima Takashi |
| 4 | Effect of silibinin on ethanol- or acetaldehyde-induced damge of mouse primary hepatocytes in vitro | 期刊论文 | Song Xiaoyu;Li Ronghua;Liu Weiwei;Hayashi Toshihiko;Mizuno Kazunori;Hattori Shunji;Fujisaki Hitomi;Ikejima Takashi |
| 5 | Silibinin protects rat pancreatic beta-cell through up-regulation of estrogen receptors' signaling against amylin- or A beta(1-42)-induced reactive oxygen species/reactive nitrogen species generation | 期刊论文 | Yang Jing;Sun Yue;Xu Fanxing;Liu Weiwei;Hayashi Toshihiko;Hattori Shunji;Ushiki Kaku Yuko;Onodera Satoshi;Tashiro Shin ichi;Ikejima Takashi |
| 6 | Estrogen receptors participate in silibinin-caused nuclear translocation of apoptosis-inducing factor in human breast cancer MCF-7 cells | 期刊论文 | Liu Weiwei;Ji Yachao;Sun Yu;Si Lingling;Fu Jianing;Hayashi Toshihiko;Onodera Satoshi;Ikejima Takashi |
| 7 | Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion | 期刊论文 | Si Lingling;Fu Jianing;Liu Weiwei;Hayashi Toshihiko;Nie Yuheng;Mizuno Kazunori;Hattori Shunji;Fujisaki Hitomi;Onodera Satoshi;Ikejima Takashi |
| 8 | Silibinin treatment protects human skin cells from UVB injury through upregulation of estrogen receptors | 期刊论文 | Liu Weiwei;Wang Fang;Li Can;Otkur Wuxiyar;Hayashi Toshihiko;Mizuno Kazunori;Hattori Shunji;Fujisaki Hitomi;Onodera Satoshi;Ikejima Takashi |
| 9 | Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic beta-cells is mediated by estrogen receptor alpha | 期刊论文 | Sun Yue;Yang Jing;Liu Weiwei;Yao Guodong;Xu Fanxing;Hayashi Toshihiko;Onodera Satoshi;Ikejima Takashi |
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