基于三元-气血论和BACE-1/GSK-3β双重抑制作用的三种土家药抗阿尔茨海默病药效物质基础研究

81573694
2015
H3218.民族药学
孟大利
面上项目
教授
沈阳药科大学
55万元
阿尔茨海默病;土家药;GSK-3β;BACE1;生物碱
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Anti-gout nor-oleanane triterpenoids from the leaves of Stauntonia brachyanthera 期刊论文 Liu Xuan-li;Li Shuang;Meng Da-li
2 The inhibitory effects of nor-oleanane triterpenoid saponins from Stauntonia brachyanthera towards UDP-glucuronosyltransferases 期刊论文 Liu Dan;Li Shuang;Qi Jia-qi;Meng Da-li;Cao Yun-feng
3 Phytochemical and cytotoxic studies on the roots of Euphorbia fischeriana 期刊论文 Shi Qun;Sun Yi wei;Meng Dali
4 Virtual screening of active compounds from Artemisia argyi and potential targets against gastric ulcer based on Network pharmacology 期刊论文 Wang Yue;Sun Yi-wei;Wang Yu-meng;Ju Yan;Meng Da-li
5 Gut Microbiota Serve As a New Therapeutic Target for Alzheimer’s Diseases 会议论文 周洪旭;孟大利
6 Revealing synergistic mechanism of multiple components in Stauntonia brachyanthera Hand.-Mazz. for gout by virtual screening and system pharmacological approach 期刊论文 Hua Qiong-qiong;Liu Ying;Liu Cai-hong;Liu Li;Meng Da-li
7 土家药大金发藓化学成分与生物活性研究 会议论文 李容;孟大利
8 毛黄堇药材的生药学研究 期刊论文 张毅;张建华;柴智;吴佳;韩凤;孟大利
9 Isoquinolines from national herb Corydalis tomentella and neuroprotective effect against lipopolysaccharide-induced BV2 microglia cells 期刊论文 Yu-Meng Wang;Wen-Zhuo Ming;Hui Liang;Ying-Jiao Wang;Yun-Hong Zhang;Da-Li Meng
10 Potential anti-gout constituents as xanthine oxidase inhibitor from the fruits of Stauntonia brachyanthera 期刊论文 Liu Dan;Wang Dandan;Yang Wei;Meng Dali
11 Isoquinolines from Corydalis tomentella from Tibet, China, possess hepatoprotective activities 期刊论文 Yingjiao Wang;Dandan Wang;Jianhua Zhang;Dan Liu;Zihao Wang;Dali Meng
12 New nor-oleanane triterpenoids from the fruits of Stauntonia brachyanthera with potential anti-inflammation activity 期刊论文 Jiaheng Lia;Kaicheng Du;Dan Liu;Dali Meng
13 Near-infrared laser triggered release of a natural flavone - eupatilin from hollow gold nanoparticles 会议论文 孙伊维;车鑫;孟大利
14 Brachyantheraoside A(8), a new natural nor-oleanane triterpenoid as a kidney-type glutaminase inhibitor from Stauntonia brachyanthera 期刊论文 Li Rong;Wei Peifeng;Wang Yue;Liu Ying;Liu Xuanli;Meng Dali
15 Potential anti-Alzheimer's disease activities of the roots of Desmodium caudatum 期刊论文 Guo Jia;Feng Xiaohe;Zhou Shaobo;Yan Wenxia;Meng Dali
16 The total triterpenoid saponins of Xanthoceras sorbifolia improve learning and memory impairments through against oxidative stress and synaptic damage 期刊论文 Ji Xue Fei;Chi Tian Yan;Liu Peng;Li Lu Yi;Xu Ji Kai;Xu Qian;Zou Li Bo;Meng Da Li
17 Caudatan A, an undescribed human kidney-type glutaminase inhibitor with tetracyclic flavan from Ohwia caudata 期刊论文 Sun Yiwei;Feng Xiaohe;Liu Xuanli;Qian Cheng;Che Xin;Cao Fei;Jin Sanshan;Meng Dali
18 降甲基三萜皂苷类化合物对葡萄糖醛酸转移酶抑制作用的研究 会议论文 刘丹;孟大利
19 Xanthoceraside hollow gold nanoparticles, green pharmaceutics preparation for poorly water-soluble natural anti-AD medicine 期刊论文 Meng Da-li;Shang Lei;Feng Xiao-he;Huang Xing-fei;Che Xin
20 Systems Pharmacological Approach to Investigate the Mechanism of Ohwia caudata for Application to Alzheimer's Disease 期刊论文 Sun Yi wei;Wang Yue;Guo Zi feng;Du Kai cheng;Meng Da li
21 Gastro-protective effect of edible plant Artemisia argyi in ethanol-induced rats via normalizing inflammatory responses and oxidative stress 期刊论文 Li Shuang;Zhou Shaobo;Yang Wei;Meng Dali
22 Chemical constituents and synergistic anti-gout studies on Eurycoma longifolia and potential mechanisms evaluation based on systemic analysis approach 期刊论文 Liu Ying;Lai Lantao;Ju Yan;Liu Caihong;Meng Dali
23 Diuretic Properties and Chemical Constituent Studies on Stauntonia brachyanthera 期刊论文 Liu Xuan Li;Wang Dan Dan;Wang Zi Hao;Meng Da Li
24 The analgesic activities of Stauntonia brachyanthera and YM11 through regulating inflammatory mediators and directly controlling the sodium channel prompt 期刊论文 Meng Dali;Wang Lei;Du Jingnan;Chen Jianchao;Chen Chao;Xu Wei;Li Chunli
25 Polyhydroxyl guaianolide terpenoids as potential NF-кB inhibitors induced cytotoxicity in human gastric adenocarcinoma cell line 期刊论文 Yi-wei Sun;Yan Ju;Cai-hong Liu;Kai-cheng Du;Da-li Meng
26 A green and facile preparation approach, licochalcone A capped on hollow gold nanoparticles, for improving the solubility and dissolution of anticancer natural product 期刊论文 Sun Yi Wei;Wang Li Hong;Meng Da Li;Che Xin
27 Xanthoceraside Could Ameliorate Alzheimer's Disease Symptoms of Rats by Affecting the Gut Microbiota Composition and Modulating the Endogenous Metabolite Levels 期刊论文 Zhou Hongxu;Tai Jingjie;Xu Haiyan;Lug Xiumei;Meng Dali
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