基于代谢组学与组合药代动力学表征的葛根芩连汤药性物质基础与配伍机制研究

81573629
2015
H3207.中药药性理论
于治国
面上项目
教授
沈阳药科大学
55万元
四气五味;药性;葛根芩连汤;代谢组学;组合药代动力学
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Rapid characterization of chemical constituents of Gansuibanxia decoction by UHPLC-FT-ICR-MS analysis 期刊论文 Yue Cui;Huanhuan Yang;Jixue Jing;Ting Liu;Roujia Wang;Fuyu Di;Fei Han;Yunli Zhao;Zhiguo Yu
2 A plasma metabonomic analysis on potential biomarker in pyrexia induced by three methods using ultra high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry 期刊论文 Ting Liu;Songhe Li;Xiumin Tian;Zhaoqin Li;Yue Cui;Fei Han;Yunli Zhao;Zhiguo Yu
3 Metabolic profiling of Gegenqinlian decoction in rat plasma, urine, bile and feces after oral administration by ultra high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry 期刊论文 Ting Liu;Xiumin Tian;Zhaoqin Li;Fei Han;Bin Ji;Yunli Zhao;Zhiguo Yu
4 Metabonomic analysis of potential plasma biomarkers in pyrexia rats after treatment with Gegenqinlian decoction, aspirin and itraconazole by UHPLC-FT-ICR-MS 期刊论文 Ting Liu;Ruiyun Li;Yue Cui;Zhiguo Yu;Yunli Zhao
5 LC-ESI-MS/MS method for simultaneous determination of eleven bioactive compounds in rat plasma after oral administration of Ling-Gui-Zhu-Gan Decoction and its application to a pharmacokinetics study 期刊论文 Bin Ji;Yunli Zhao;Peipei Yu;Bin Yang;Ceng Zhou;Zhiguo Yu
6 Investigation of the mechanism of incompatible herb pair gansui-gancao-induced hepatotoxicity and nephrotoxicity and the attenuated effect of gansuibanxia decoction by UHPLC-FT-ICR-MS-based plasma metabonomic analysis 期刊论文 Yue Cui;Roujia Wang;Ye Zhang;Ting Liu;Fei Han;Ruiyun Li;Nan Zhang;Yunli Zhao;Zhiguo Yu
7 Detection of chemical constituents in Gegenqinlian decoction by ultra-high performance liquid chromatography coupled with Fourier transform ion cyclotron resonance mass spectrometry 期刊论文 Ting Liu;Yue Cui;Xiumin Tian;Songhe Li;Fei Han;Bin Ji;Yunli Zhao;Zhiguo Yu
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