PDE5抑制剂抑制小胶质细胞活化抗脑缺血的cGMP通路相关机制研究
81102455
2011
H3504.抗炎与免疫药物药理
杨静玉
青年科学基金项目
教授
沈阳药科大学
25万元
PDE5抑制剂;cGMP;LPS;脑缺血;小胶质细胞活化
2012-01-01到2014-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Yonkenafil: A novel phosphodiesterase type 5 inhibitor induces neuronal network potentiation by a cGMP-dependent Nogo-R axis in acute experimental stroke | 期刊论文 | Chen, Xuemei|Wang, Nannan|Liu, Yueyang|Liu, Yinglu|Zhang, Tianyu|Zhu, Lei|Wang, Yongfeng|Wu, Chunfu|Yang, Jingyu| |
| 2 | A self-propelling cycle mediated by reactive oxide species and nitric oxide exists in LPS-activated microglia | 期刊论文 | Zhang Lijia|Zhao Siqi|Wang Xiaoxiao|Wu Chunfu|Yang Jingyu| |
| 3 | Neuroprotection by sildenafil: neuronal networks potentiation in acute experimental stroke | 期刊论文 | Chen, Xue-mei|Wang, Nan-nan|Zhang, Tian-yu|Wu, Chun-fu|Yang, Jing-yu| |
| 4 | A self-propelling cycle mediated by reactive oxide species and nitric oxide exists in LPS-activated microglia | 期刊论文 | Lijia Zhang|Siqi Zhao|Xiaoxiao Wang|Chunfu Wu|Jingyu Yang| |
| 5 | Neuroprotection by sildenafil: neuronal networks potentiation in acute experimental stroke. | 期刊论文 | Chen, Xue-Mei|Wang, Nan-Nan|Zhang, Tian-Yu|Wang, Fang|Wu, Chun-Fu|Yang, Jing-Yu| |
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