自组装环境敏感型纳米球晶介导STAT3靶标肽的胞内转运及重建肿瘤免疫微环境的基础研究

31671020
2016
C1007.纳米生物学
石凯
面上项目
教授
沈阳药科大学
62万元
多肽;肿瘤微环境;生物纳米材料;肿瘤疫苗;免疫治疗
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Polymeric metformin and its use as a therapeutic agent and as a delivery vehicle 专利 Leaf Huang;Yi Zhao;Shutao Guo;Kai Shi
2 胰岛素-磷脂复合物的制备及其理化性质的研究 期刊论文 毕洪书;房燕;高珊;杨东娟;石凯
3 Cleavable PEGylation: A Strategy for Overcoming the "PEG Dilemma" in Efficient Drug Delivery 期刊论文 Fang Yan;Xue Jianxiu;Gao Shan;Lu Anqi;Shi Kai
4 Dual Functional LipoMET Mediates Envelope-type Nanoparticles to Combinational Oncogene Silencing and Tumor Growth Inhibition 期刊论文 Kai Shi;Yi Zhao;Lei Miao;Andrew Satterlee;Matthew Haynes;Cong Luo;Sara Musetti;Leaf Huang
5 药剂学 专著 李范珠;石凯
6 Current developments in drug delivery with thermosensitive liposomes 期刊论文 Bi Hongshu;Xue Jianxiu;Jiang Hong;Gao Shan;Yang Dongjuan;Fang Yan;Shi Kai
7 Engineering nanoparticles for targeted remodeling of the tumor microenvironment to improve cancer immunotherapy 期刊论文 Shan Gao;Dongjuan Yang;Yan Fang;Xiaojie Lin;Xuechao Jin;Qi Wang;Xiyan Wang;Liyuan Ke;Kai Shi
8 药学(师)应试指南 专著 赵春杰;石凯
9 Nanovaccines for Remodeling the Suppressive Tumor Microenvironment: New Horizons in Cancer Immunotherapy 期刊论文 Shi Kai;Haynes Matthew;Huang Leaf
10 壳-核结构多柔比星脂质磷酸钙纳米粒的制备及体外性能评价 期刊论文 薛建秀;毕洪书;李雨爱;陈瑶;刘晓庆;徐正奇;潘虎威;石凯
11 基于生物大分子自组装过程的递药系统设计与评价 会议论文 石凯
12 双功能LipoMET信封式纳米粒介导的组合基因沉默和肿瘤生长抑制 会议论文 石凯
13 高分子メトホルミンならびに治療用薬剤としておよび送達媒体としてのその使用 专利 フアン，リーフ;ヂャオ，イー;グオ，シュータオ;シー，カイ
14 聚合物二甲双胍和其作为治疗剂和作为递送载体的用途 专利 黄力夫;赵熠;郭述涛;石凯
15 Gastrointestinal Responsive Polymeric Nanoparticles for Oral Delivery of Insulin: Optimized Preparation, Characterization, and In Vivo Evaluation 期刊论文 Fang Yan;Wang Qi;Lin Xiaojie;Jin Xuechao;Yang Dongjuan;Gao Shan;Wang Xiyan;Yang Mingshi;Shi Kai
16 Inorganic kernel - Supported asymmetric hybrid vesicles for targeting delivery of STAT3-decoy oligonucleotides to overcome anti-HER2 therapeutic resistance of BT474R 期刊论文 Shi Kai;Fang Yan;Gao Shan;Yang Dongjuan;Bi Hongshu;Xue Jianxiu;Lu Anqi;Li Yuai;Ke Liyuan;Lin Xiaojie;Jin Xuechao;Li Min
17 Inorganic Kernel-Reconstituted Lipoprotein Biomimetic Nanovehicles Enable Efficient Targeting "Trojan Horse" Delivery of STAT3-Decoy Oligonucleotide for Overcoming TRAIL Resistance 期刊论文 Shi Kai;Xue Jianxiu;Fang Yan;Bi Hongshu;Gao Shan;Yang Dongjuan;Lu Anqi;Li Yuai;Chen Yao;Ke Liyuan
18 The pi-pi stacking-guided supramolecular self-assembly of nanomedicine for effective delivery of antineoplastic therapies 期刊论文 Dongjuan Yang;Shan Gao;Yan Fang;Xiaojie Lin;Xuechao Jin;Xiyan Wang;Liyuan Ke;Kai Shi
19 Design and Fabrication of Dual Redox Responsive Nanoparticles with Diselenide Linkage Combined Photodynamically 期刊论文 Yan Fang;Xiaojie Lin;Xuechao Jin;Dongjuan Yang;Shan Gao;Kai Shi;Mingshi Yang
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