Hsp90与共伴侣Cdc37通过Erk1/2及p38信号通路调控人精子获能的分子机制研究

81771647
2017
H0405.精子发生异常与男性不育
倪崖
面上项目
研究员
杭州医学院
55万元
丝裂原活化蛋白激酶信号通路;精子获能;细胞分裂周期蛋白37;磷酸化;热休克蛋白90
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Emerging role for SRC family kinases in junction dynamics during spermatogenesis 期刊论文 Xiao Xiang;Yang Yue;Mao Baiping;Cheng C Yan;Ni Ya
2 KCNQ1 Potassium Channel Expressed in Human Sperm Is Involved in Sperm Motility, Acrosome Reaction, Protein Tyrosine Phosphorylation, and Ion Homeostasis During Capacitation. 期刊论文 Gao Tian;Li Kun;Liang Fei;Yu Jianmin;Liu Ajuan;Ni Ya;Sun Peibei
3 四川省科学技术进步奖 奖励 许文明;秦朗;张小虎;倪崖;文帮芬;汪燕;张娅;陈小章;孙培蓓;童煜;肖秀君;谯小勇
4 Novel distance-progesterone-combined selection approach improves human sperm quality. 期刊论文 Li Kun;Li Rui;Ni Ya;Sun Peibei;Liu Ye;Zhang Dan;Huang Hefeng
5 The Seminiferous Epithelial Cycle of Spermatogenesis: Role of Non-receptor Tyrosine Kinases. 期刊论文 Xiao Xiang;Zheng Dongwang;Liang Fei;Ying Shibo;Sun Peibei;Yu Jianmin;Ni Ya
6 Protein kinases regulate hyperactivated motility of human sperm. 期刊论文 Wang Ya-Yan;Sun Pei-Bei;Li Kun;Gao Tian;Zheng Dong-Wang;Wu Fang-Ping;Liu A-Juan;Ni Ya
7 Hsp90 interacts with Cdc37, is phosphorylated by PKA/PKC, and regulates Src phosphorylation in human sperm capacitation 期刊论文 Li Kun;Sun Peibei;Wang Yayan;Gao Tian;Zheng Dongwang;Liu Ajuan;Ni Ya
8 Hsp90 modulates human sperm capacitation via the Erk1/2 and p38 MAPK signaling pathways. 期刊论文 Sun Peibei;Wang Yayan;Gao Tian;Li Kun;Zheng Dongwang;Liu Ajuan;Ni Ya
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