LncRNA J13Rik调控TXNIP/NLRP3信号通路介导肠缺血再灌注脑损伤后 小胶质细胞极化的机制研究

81873930
2018
H1602.器官功能衰竭与支持
周军
面上项目
教授
西南医科大学
57万元
小胶质细胞极化;多脏器功能衰竭;硫氧还蛋白互作蛋白;肠缺血再灌注损伤;长链非编码J13Rik
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Thioredoxin-Interacting Protein (TXNIP) Knockdown Protects against Sepsis-Induced Brain Injury and Cognitive Decline in Mice by Suppressing Oxidative Stress and Neuroinflammation 期刊论文 Yu Zhang;Cheng-Jun Xing;Xiao Liu;Ya-Hong Li;Jing Jia;Jianguo Feng;Cheng-Jie Yang;Ye Chen;Jun Zhou
2 Amelioration of Coagulation Disorders and Inflammation by Hydrogen-Rich Solution Reduces Intestinal Ischemia/Reperfusion Injury in Rats through NF-κB/NLRP3 Pathway. 期刊论文 Ling Yang;Yan Guo;Xin Fan;Ye Chen;Bo Yang;Ke-Xuan Liu;Jun Zhou
3 丙泊酚预处理对脓毒症大鼠认知功能的影响 期刊论文 杨博;张茂芮;周军
4 Activation of LRP1 Ameliorates Cerebral Ischemia/Reperfusion Injury and Cognitive Decline by Suppressing Neuroinflammation and Oxidative Stress through TXNIP/NLRP3 Signaling Pathway in Mice 期刊论文 Cheng-Jie Yang;Xin Li;Xiao-Qing Feng;Ye Chen;Jianguo Feng;Jing Jia;Ji-Cheng Wei;Jun Zhou
5 The role of AMPK-Sirt1-autophagy pathway in the intestinal protection process by propofol against regional ischemia/reperfusion injury in rats. 期刊论文 Xiao Liu;Bo Yang;Ya-Fang Tan;Jian-Guo Feng;Jing Jia;Cheng-Jie Yang;Ye Chen;Mao-Hua Wang;Jun Zhou
6 利拉鲁肽的器官保护作用及研究进展 期刊论文 黄俊颖;管少迪;伍虹燕;尹颢霖;罗涛;周军
7 RBM3 Increases Cell Survival but Disrupts Tight Junction of Microvascular Endothelial Cells in Acute Lung Injury 期刊论文 Jianguo Feng;Jianguo Feng;Xiaoli Yang;Feiyu Long;Jun Zhou;Yi Liao;Maohua Wang
8 Trigeminal neuralgia causes neurodegeneration in rats associated with upregulation of the CD95/CD95L pathway 期刊论文 Lu Wang;Menghong Long;Maohua Wang;Shuangchun Peng;Guangxiang Chen;Jun Zhou;Cehua Ou
9 Irisin Contributes to the Hepatoprotection of Dexmedetomidine during Intestinal Ischemia/Reperfusion 期刊论文 Xin Fan;Juan Du;Mao-Hua Wang;Jia-Man Li;Bo Yang;Ye Chen;Jun-Chao Dai;Chunxiang Zhang;Jun Zhou
10 富氢盐水对大鼠肠缺血再灌注凝血功能的影响 期刊论文 范馨;杜娟;杨博;周军
11 Irisin pretreatment ameliorates intestinal ischemia/reperfusion injury in mice through activation of the Nrf2 pathway 期刊论文 Juan Du;Xin Fan;Bo Yang;Ye Chen;Ke-Xuan Liu;Jun Zhou
12 氢气对器官的保护作用及机制的研究进展 期刊论文 王怡;卫静文;杨珏玺;吴松睿;周军
13 Dexmedetomidine alleviates neuroinflammation, restores sleep disorders and neurobehavioral abnormalities in rats with minimal hepatic encephalopathy 期刊论文 Zhang Yu;Tan Su-Lan;Du Juan;Chen Ye;Jia Jing;Feng Jian-Guo;Liu Ke-Xuan;Zhou Jun
14 Dexmedetomidine Ameliorated Cognitive Dysfunction Induced by Intestinal Ischemia Reperfusion in Mice with Possible Relation to the Anti-inflammatory Effect Through the Locus Coeruleus Norepinephrine System 期刊论文 Gang Li;Jun Zhou;Jicheng Wei;Bin Liu
15 Melatonin alleviates intestinal injury, neuroinflammation and cognitive dysfunction caused by intestinal ischemia/reperfusion. 期刊论文 Bo Yang;Li-Yin Zhang;Ye Chen;Yi-Ping Bai;Jing Jia;Jian-Guo Feng;Ke-Xuan Liu;Jun Zhou
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