地榆单体TMEA通过c-kit/PI3K/Akt途径促巨核细胞分化的分子机制

81774013
2017
H3219.中药学研究新技术与新方法
吴建明
面上项目
教授
西南医科大学
55万元
三甲基逆没食子酸;c-kit/PI3K/Akt通路;血小板生成;巨核细胞分化;地榆
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Whole transcriptome sequencing and integrated network analysis elucidates the effects of 3,8-Di-O-methylellagic acid 2-O-glucoside derived from Sanguisorba offcinalis L., a novel differentiation inducer on erythroleukemia cells. 期刊论文 Long Wang;Liu Sha;Li Xiao-Xuan;Shen Xin;Zeng Jing;Luo Jie-Si;Li Ke-Ru;Wu An-Guo;Yu Lu;Qin Da-Lian;Hu Guang-Qiang;Yang Jing;Wu Jian-Ming
2 地榆活性成分在制备抗肿瘤的药物中的用途 专利 吴建明;秦大莲;柏冲飞;杨靖;孙悦珊
3 A rapid and sensitive UHPLC-MS/MS method for the determination of ziyuglycoside I and its application in a preliminary pharmacokinetic study in healthy and leukopenic rats 期刊论文 Zhu Lin-jie;Chen Lin;Bai Chong-fei;Wu An-guo;Liang Si-cheng;Huang Fei-hong;Cao Shou-song;Yang Le;Zou Wen-jun;Wu Jian-ming
4 Network Pharmacology and Pharmacological Evaluation Reveals the Mechanism of the Sanguisorba Officinalis in Suppressing Hepatocellular Carcinoma 期刊论文 Nan Jiang;Hong Li;Yueshan Sun;Jing Zeng;Fei Yang;Fahsai Kantawong;Jianming Wu
5 TMEA, a Polyphenol in Sanguisorba officinalis, Promotes Thrombocytopoiesis by Upregulating PI3K/Akt Signaling. 期刊论文 Li Hong;Jiang Xueqin;Shen Xin;Sun Yueshan;Jiang Nan;Zeng Jing;Lin Jing;Yue Liang;Lai Jia;Li Yan;Wu Anguo;Wang Long;Qin Dalian;Huang Feihong;Mei Qibing;Yang Jing;Wu Jianming
6 3,4'-O-二甲基逆没食子酸、其衍生物及其制药用途 专利 吴建明;王龙;杨靖;吴安国;秦大莲;姜雪琴;李晓璇;刘莎;曹娅
7 Targeting autophagy in ethnomedicine against human diseases. 期刊论文 Lai Jia;Tang Yong;Yang Fei;Chen Jianping;Huang Fei-Hong;Yang Jing;Wang Long;Qin Dalian;Law Betty Yuen-Kwan;Wu An-Guo;Wu Jian-Ming
8 Antitumor Effects of Trimethylellagic Acid Isolated From Sanguisorba officinalis L. on Colorectal Cancer via Angiogenesis Inhibition and Apoptosis Induction 期刊论文 Bai Chongfei;Sun Yueshan;Pan Xianchao;Yang Jing;Li Xiaoxuan;Wu Anguo;Qin Dalian;Cao Shousong;Zou Wenjun;Wu Jianming
9 Elucidation of the molecular mechanism of Sanguisorba Officinalis L. against leukopenia based on network pharmacology 期刊论文 Long Wang;Hong Li;Xin Shen;Jing Zeng;Liang Yue;Jing Lin;Jing Yang;Wenjun Zou;Yan Li;Dalian Qin;Anguo Wu;Jianming Wu
10 A Comprehensive Review of Genus Sanguisorba: Traditional Uses, Chemical Constituents and Medical Applications. 期刊论文 Zhou Ping;Li Jingyan;Chen Qi;Wang Long;Yang Jing;Wu Anguo;Jiang Nan;Liu Yuanzhi;Chen Jianping;Zou Wenjun;Zeng Jing;Wu Jianming
11 Efficacy and Safety of Avatrombopag in Patients With Thrombocytopenia: A Systematic Review and Meta-Analysis of Randomized Controlled Trials 期刊论文 Li Chunlu;Li Xiaoxuan;Huang Feihong;Yang Jing;Wu Anguo;Wang Long;Qin Dalian;Zou Wenjun;Wu Jianming
12 地榆成分3,3'-二甲氧基逆没食子酸-4-木糖苷对NIH3T3细胞促增殖作用及其机制研究 期刊论文 柏冲飞;陈琳;孙悦珊;李晓璇;杨靖;吴安国;邹文俊;吴建明
13 地榆活性成分DMAG 促血小板生成作用及其分子机制 会议论文 Yueshan Sun;Xueqin Jiang;Rong Pan;Dalian Qin;Rui Xiong;Yiling Wang;Wenqiao Qiu;Anguo Wu;Jianming Wu
14 Whole transcriptome analysis identifies differentially regulated networks during proliferation inhibition and megakaryocytic differentiation of AML cell induced by DMAG 会议论文 Wang Long;Li Xiao-xuan;Liu Sha;Yang Jing;Wu Jian-ming
15 地榆活性成分在制备促进创面愈合药物中的用途 专利 吴建明;陈琳;柏冲飞;孙悦珊;秦大莲;杨靖
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