miR-299a-5p/NF-κB调控环路促进睾丸Leydig细胞衰老的分子机制研究

91949123
2019
H1901.衰老机制与调控
陈浩林
重大研究计划
研究员
温州医科大学
68万元
炎症;老化;睾丸;迟发型性腺功能衰退症;Leydig细胞
2020-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 High-fidelity reprogramming into Leydig-like cells by CRISPR activation and paracrine factors 期刊论文 Li Z;Fan Y;Xie C;Liu J;Guan X;Li S;Huang Y;Zeng R;Chen H;Su Z
2 Single-cell RNA sequencing of adult rat testes after Leydig cell elimination and restoration 期刊论文 Guan X;Ji M;Wen Xin;Huang F;Zhao X;Chen D;Shao J;Wang J;Xie J;Tian J;Lin H;Duan P;Barry R.;Su Z;Chen H
3 Effects of Midazolam on the Development of Adult Leydig Cells From Stem Cells In Vitro 期刊论文 Zhao X;Ji M;Wen X;Chen D;Huang F;Guan X;Tian J;Xie J;Shao J;Wang J;Huang L;Lin H;Ye L;Chen H
4 通过双酚A暴露重置脑垂体稳态增加成年大鼠血清睾酮的测试方法 专利 陈浩林;陈丹;管小菊;赵星仪;黄福
5 Stem Leydig Cells in the Adult Testis: Characterization, Regulation and Potential Applications 期刊论文 Chen P;Zirkin BR;Chen H
6 防飞溅眼镜 专利 管小菊;陈浩林;温馨;黄福;季敏鹏;赵星仪;陈丹;汪婕遐;邵晶晶;谢佳佳
7 Effects of Gestational Exposure to Perfluorooctane Sulfonate on the Lung Development of Offspring Rats 期刊论文 Huishan Zhang;Hemin Lu;Lin Yu;Jiexin Yuan;Qin Shan;Cong Li;Ren-Shan Ge;Haolin Chen;Leping Ye
8 Phthalate inhibits Leydig cell differentiation and promotes adipocyte differentiation 期刊论文 Hao X;Guan X;ZhaoX;Ji M;Wen X;Chen P;Chen F;Yang J;Lian Q;Ye L;Chen H
9 Pubertal Bisphenol A exposure increases adult rat serum testosterone by resetting pituitary homeostasis 期刊论文 Chen D;Zhao X;Huang F;Guan X;Tian J;Ji M;Wen X;Shao J;Xie J;Wang J;Chen H
10 咪达唑仑对体外培养的睾丸间质细胞发育影响的试验方法 专利 陈浩林;季敏鹏;赵星仪;温馨;陈丹
11 Differentiation of seminiferous tubule-associated stem cells into leydig cell and myoid cell lineages 期刊论文 Zhao X;Wen X;Ji M;Guan X;Chen P;Hao X;Chen F;Hu Y;Duan P;Ge RS;Chen H
12 Isolation of Leydig cells from adult rat testes by magnetic-activated cell sorting protocol based on prolactin receptor expression 期刊论文 Ji M;Chen D;Zhao X;Huang F;Guan X;Wen X;Wang J;Shao J;Xie J;Shan D;Cao S;Chen C;Chen H
13 大鼠睾丸间质Leydig细胞的分离方法 专利 陈浩林;季敏鹏;赵星仪;温馨
14 Generation of Leydig-like cells: approaches, characterization, and challenges 期刊论文 Li Z;Lu J;Li S;Chen H;Su Z
15 Identification of Rat Testicular Leydig Precursor Cells by Single-Cell-RNA-Sequence Analysis 期刊论文 Guan X;Chen P;Ji M;Wen X;Chen D;Zhao X;Huang F;Wang J;Shao J;Xie J;Zhao X;Chen F;Tian J;Lin H;Zirkin BR;Duan P;Su Z;Chen H
16 用于固定大鼠睾丸进行注射的固定装置 专利 陈浩林;林函;郝欣蕊;管小菊
17 用于定位大鼠进行灌胃操作的固定装置 专利 陈浩林;连庆泉;林函;郝欣蕊
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