具有代谢调控功能新型旁分泌生长因子FGFs的发现及降糖机制研究
81874323
2018
H3507.代谢性疾病药物药理
黄志锋
面上项目
教授
温州医科大学
57万元
成纤维细胞生长因子;共性特征;代谢调控;降糖机制;旁分泌
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Paracrine-endocrine FGF chimeras as potent therapeutics for metabolic diseases | 期刊论文 | Longwei Zhao;Jianlou Niu;Huan Lin;Jing Zhao;Yang Liu;Zihui Song;Congshang Xiang;Xiaojie Wang;Yong Yang;Xiaokun Li;Moosa Mohammadi;Zhifeng Huang |
| 2 | Curtailing FGF19’s mitogenicity by suppressing its receptor dimerization ability | 期刊论文 | Jianlou Niu;Jing Zhao;Jiamin Wu;Guanting Qiao;Junlian Gu;Chuanren Zhou;Qi Li;Lei Ying;Dezhong Wang;Huan Lin;Xiaokun Li;Moosa Mohammadi;Zhifeng Huang |
| 3 | FGF1ΔHBS prevents diabetic cardiomyopathy by maintaining mitochondrial homeostasis and reducing oxidative stress via AMPK/Nur77 suppression | 期刊论文 | Dezhong Wang;Yuan Yin;Shuyi Wang;Tianyang Zhao;Fanghua Gong;Yushuo Zhao;Beibei Wang;Yuli Huang;Zizhao Cheng;Guanghui Zhu;Zengshou Wang;Yang Wang;Jun Ren;Guang Liang;Xiaokun Li;Zhifeng Huang |
| 4 | The application of FGF4 and FGFR1 binding ligands in diabetes | 专利 | 黄志锋;沈伟;孙红彬;李校堃;温红 |
| 5 | Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects | 期刊论文 | Lei Ying;Luyao Wang;Kaiwen Guo;Yushu Hou;Na Li;Shuyi Wang;Xingfeng Liu;Qijin Zhao;Jie Zhou;Longwei Zhao;Jianlou Niu;Chuchu Chen;Lintao Song;Shaocong Hou;Lijuan Kong;Xiaokun Li;Jun Ren;Pingping Li;Moosa Mohammadi;Zhifeng Huang |
| 6 | FGF4 protects the liver from nonalcoholic fatty liver disease by activating the AMP-activated protein kinase-Caspase 6 signal axis | 期刊论文 | Lintao Song;Luyao Wang;Yushu Hou;Jie Zhou;Chuchu Chen;Xianxi Ye;Wenliya Dong;Huan Gao;Yi Liu;Guanting Qiao;Tongtong Pan;Qiong Chen;Yu Cao;Fengjiao Hu;Zhiheng Rao;Yajing Chen;Yu Han;Minghua Zheng;Yongde Luo;Xiaokun Li;Yongping Chen;Zhifeng Huang |
| 7 | FGF4及其应用 | 专利 | 黄志锋;应磊;王璐瑶;侯煜姝;周洁;金辉;李校堃;穆萨.穆罕穆迪 |
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