抑制TRAF6缓解高糖诱导的炎症反应和糖尿病肾病的作用机制研究

81872918
2018
H3507.代谢性疾病药物药理
张亚利
面上项目
副研究员
温州医科大学
55万元
炎症反应;糖尿病肾病;肾小管上皮细胞;TNF受体相关因子6;高糖
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 A novel resveratrol analog PA19 attenuates obesity-induced cardiac and renal injury by inhibiting inflammation and inflammatory cell infiltration 期刊论文 Zhang Wenxin;Chen Hongjin;Sun Chuchu;Wu Beibei;Bai Bin;Liu Hui;Shan Xiaoou;Liang Guang;Zhang Yali
2 Arachidonic acid inhibits inflammatory responses by binding to myeloid differentiation factor-2 (MD2) and preventing MD2/toll-like receptor 4 signaling activation 期刊论文 Yali Zhang;Hongjin Chen;Wenxin Zhang;Yan Cai;Peiren Shan;Di Wu;Bing Zhang;Hui Liu;Zia A. Khan;Guang Liang
3 Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2 期刊论文 Zhang Yali;Zhang Wenxin;Yan Jueqian;Tang Yelin;Jia Wenjing;Xu Zhengwei;Xu Mingjiang;Chattipakorn Nipon;Wang Yi;Feng Jianpeng;Liu Zhiguo;Liang Guang
4 Kaempferol reduces K63-linked polyubiquitination to inhibit nuclear factor-kappa B and inflammatory responses in acute lung injury in mice 期刊论文 Qian Jianchang;Chen Xuemei;Chen Xiaojun;Sun Chuchu;Jiang Yuchen;Qian Yuanyuan;Zhang Yali;Khan Zia;Zhou Jianmin;Liang Guang;Zheng Chao
5 Kaempferol attenuates streptozotocin-induced diabetic nephropathy by downregulating TRAF6 expression: The role of TRAF6 in diabetic nephropathy 期刊论文 Luo Wu;Chen Xiaojun;Ye Lin;Chen Xuemei;Jia Wenjing;Zhao Yanni;Samorodov Aleksandr V;Zhang Yali;Hu Xueting;Zhuang Fei;Qian Jianchang;Zheng Chao;Liang Guang;Wang Yi
6 Pharmacological inhibition of MyD88 suppresses inflammation in tubular epithelial cells and prevents diabetic nephropathy in experimental mice 期刊论文 Zhang Qiuyan;Xu Sujing;Qian Jianchang;Yang Libin;Chen Pengqin;Wang Yi;Hu Xiang;Zhang Yali;Luo Wu;Liang Guang
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