改善骨细胞再生微环境的三维复合支撑骨架MSCs+dBECM-PGA+HA对于骨创伤的修复作用及其机制研究

81772316
2017
H0603.骨、关节、软组织医用材料
赵应征
面上项目
教授
温州医科大学
55万元
聚谷氨酸-羟基磷灰石复合材料;骨细胞再生微环境;骨创伤修复;骨髓间充质干细胞;骨脱细胞基质
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 引流孔医用贴 专利 赵应征;肖健;章晓东;鲁翠涛;徐荷林;吴疆;张宏宇;杨靖靖;殷佳玉
2 Recent development and biomedical applications of decellularized extracellular matrix biomaterials 期刊论文 Yao Qing;Zheng Ya Wen;Lan Qing Hua;Kou Longfa;Xu He Lin;Zhao Ying Zheng
3 一种神经单元球形支架及其制备 专利 赵应征;鲁翠涛;肖健;虞希冲;徐荷林;杨伟;张宏宇;杨靖靖;许洁;范子梁;陈翩翩
4 Bioactive Factors-imprinted Scaffold Vehicles for Promoting Bone Healing: The Potential Strategies and the Confronted Challenges for Clinical Production 期刊论文 Peng-Peng Xue;Jian-dong Yuan;Qing Yao;Ying-Zheng Zhao;He-Lin Xu
5 一种去细胞化软骨支架及其制备方法 专利 赵应征;鲁翠涛;肖健;徐荷林;陈翩翩;许洁;杨靖靖;范子梁
6 低免疫源性骨缺损部位填充材料及其制备方法 专利 赵应征;鲁翠涛;徐荷林;姚情;夏清海;诸葛德力;杨外庚
7 一种促进细胞和器官移植后血管重建的生物胶及其制备方法 专利 赵应征;傅红兴;朱群燕;刘成洋;蒋煊;鲁翠涛
8 一种骨修复材料及其制备方法 专利 赵应征;鲁翠涛;徐荷林;姚情;杨外庚;陈睿
9 Magnetic PLGA microspheres loaded with SPIONs promoted the reconstruction of bone defects through regulating the bone mesenchymal stem cells under an external magnetic field 期刊论文 Zhao Ying-Zheng;Chen Rui;Xue Peng-Peng;Luo Lan-Zi;Zhong Bin;Tong Meng-Qi;Chen Bin;Yao Qing;Yuan Jian-Dong;Xu He-Lin
10 Pharmacological actions and therapeutic potentials of bilirubin in islet transplantation for the treatment of diabetes 期刊论文 Yao Qing;Jiang Xue;Kou Longfa;Samuriwo Adelaide T;Xu He Lin;Zhao Ying Zheng
11 一种维持组织超微结构和营养微环境的脱细胞试剂盒 专利 赵应征;陈翩翩;徐荷林;林倩;朱群燕;金冰慧;沈碧欣;诸葛德力;鲁翠涛
12 HA/MgO nanocrystal-based hybrid hydrogel with high mechanical strength and osteoinductive potential for bone reconstruction in diabetic rats 期刊论文 Chen Rui;Chen Hang-Bo;Xue Peng-Peng;Yang Wai-Geng;Luo Lan-Zi;Tong Meng-Qi;Zhong Bin;Xu He-Lin;Zhao Ying-Zheng;Yuan Jian-Dong
13 Thiolated gamma-polyglutamic acid as a bioadhesive hydrogel-forming material: evaluation of gelation, bioadhesive properties and sustained release of KGF in the repair of injured corneas 期刊论文 Xu He Lin;Tong Meng Qi;Wang Li Fen;Chen Rui;Li Xin Ze;Sohawon Yasin;Yao Qing;Xiao Jian;Zhao Ying Zheng
14 Sustained-release of FGF-2 from a hybrid hydrogel of heparin-poloxamer and decellular matrix promotes the neuroprotective effects of proteins after spinal injury 期刊论文 Xu He-Lin;Tian Fu-Rong;Xiao Jian;Chen Pian-Pian;Xu Jie;Fan Zi-Liang;Yang Jing-Jing;Lu Cui-Tao;Zhao Ying-Zheng
15 Bone-Inspired Tube Filling Decellularized Matrix of Toad Cartilage Provided an Osteoinductive Microenvironment for Mesenchymal Stem Cells to Facilitate the Radius Defect Repair of Rabbit 期刊论文 Xu He-Lin;Yang Wai-Geng;Chen Pian-Pian;Chen Rui;Xue Peng-Peng;Wang Li-Fen;Yuan Jian-Dong;Yao Qing;Chen Bin;Zhao Ying-Zheng
16 一种肌肤护理用丝素蛋白水凝胶及其制备方法 专利 赵应征;鲁翠涛;肖健;徐荷林;杨伟;虞希冲;傅红兴;胡淑平;姜义娜
17 心脑系统疾病的生物大分子药物高效治疗系统 奖励 赵应征;鲁翠涛;肖健;李校堃;王海彬;杨伟;虞希冲
18 治疗骨性关节炎的一氧化氮原位水凝胶 专利 赵应征;鲁翠涛;徐荷林;姚情;陈睿;兰清华
19 Exploiting crosslinked decellularized matrix to achieve uterus regeneration and construction 期刊论文 Yao Qing;Zheng Ya-Wen;Lin Hui-Long;Lan Qing-Hua;Huang Zhi-Wei;Wang Li-Fen;Chen Rui;Xiao Jian;Kou Longfa;Xu He-Lin;Zhao Ying-Zheng
20 基于生物材料与制剂技术的创伤修复新产品研发和应用 奖励 肖健;林才;赵应征;吴疆;姜丽萍;王晓杰;吴洪信;张宏宇;夏卫东;徐荷林;陈大庆;王健;耿武军
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