基于NRL基因敲入的人类胚胎干细胞定向分化为视杆细胞
81700885
2017
H1309.眼科学研究新技术与新方法
葛香连
青年科学基金项目
实验师
温州医科大学
20万元
诱导分化;人类胚胎干细胞;视网膜色素变性;NRL;视杆细胞
2018-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Engineering the Direct Repeat Sequence of crRNA for Optimization of FnCpf1-Mediated Genome Editing in Human Cells. | 期刊论文 | Lin Li;He Xiubin;Zhao Tianyuan;Gu Lingkai;Liu Yeqing;Liu Xiaoyu;Liu Hongyan;Yang Fayu;Tu Mengjun;Tang Lianchao;Ge Xianglian;Liu Changbao;Zhao Junzhao;Song Zongming;Qu Jia;Gu Feng |
| 2 | SaCas9 Requires 5-NNGRRT-3 PAM for Sufficient Cleavage and Possesses Higher Cleavage Activity than SpCas9 or FnCpf1 in Human Cells | 期刊论文 | Xie Haihua;Tang Lianchao;He Xiubin;Liu Xiexie;Zhou Chenchen;Liu Junjie;Ge Xianglian;Li Jin;Liu Changbao;Zhao Junzhao;Qu Jia;Song Zongming;Gu Feng |
| 3 | Functional non-homologous end joining patterns triggered by CRISPR/Cas9 in human cells | 期刊论文 | Yang Fayu;Ge Xianglian;He Xiubin;Liu Xiexie;Zhou Chenchen;Sun Huihui;Zhang Junsong;Zhao Junzhao;Song Zongming;Qu Jia;Liu Changbao;Gu Feng |
| 4 | High-fidelity SaCas9 identified by directional screening in human cells | 期刊论文 | Xie Haihua;Ge Xianglian;Yang Fayu;Wang Bang;Li Shuang;Duan Jinzhi;Lv Xiujuan;Cheng Congsheng;Song Zongming;Liu Changbao;Zhao Junzhao;Zhang Yu;Wu Jinyu;Gao Caixia;Zhang Jinwei;Gu Feng |
| 5 | Recapitulating X-Linked Juvenile Retinoschisis in Mouse Model by Knock-In Patient-Specific Novel Mutation | 期刊论文 | Chen Ding;Xu Tao;Tu Mengjun;Xu Jinlin;Zhou Chenchen;Cheng Lulu;Yang Ruqing;Yang Tanchu;Zheng Weiwei;He Xiubin;Deng Ruzhi;Ge Xianglian;Li Jin;Song Zongming;Zhao Junzhao;Gu Feng |
| 6 | A Single Multiplex crRNA Array for FnCpf1-Mediated Human Genome Editing | 期刊论文 | Sun Huihui;Li Fanfan;Liu Jie;Yang Fayu;Zeng Zhenhai;Lv Xiujuan;Tu Mengjun;Liu Yeqing;Ge Xianglian;Liu Changbao;Zhao Junzhao;Zhang Zongduan;Qu Jia;Song Zongming;Gu Feng |
查看更多信息请先登录或注册
