DNMT1的异常表达机制及其对帕金森病相关基因调控的研究
81571087
2015
H0904.运动障碍性疾病
张雄
面上项目
教授
温州医科大学
57万元
帕金森氏病;表观遗传学;DNA甲基化
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Prioritized brain selenium retention and selenoprotein expression: Nutritional insights into Parkinson's disease | 期刊论文 | Zhang Xiong;Liu Rong Pei;Cheng Wen Hsing;Zhu Jian Hong |
| 2 | Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2 | 期刊论文 | Lai Jun-Mei;Zhang Xiong;Liu Fang-Fang;Yang Rui;Li Shen-Yu;Zhu Lan-Bing;Zou Ming;Cheng Wen-Hsing;Zhu Jian-Hong |
| 3 | Selenotranscriptomic Analyses Identify Signature Selenoproteins in Brain Regions in a Mouse Model of Parkinson's Disease | 期刊论文 | Zhang Xiong;Ye Yang-Lie;Zhu Hui;Sun Sheng-Nan;Zheng Jing;Fan Hui-Hui;Wu Hong-Mei;Chen Song-Fang;Cheng Wen-Hsing;Zhu Jian-Hong |
| 4 | Reduced Circulating Levels of miR-433 and miR-133b Are Potential Biomarkers for Parkinson's Disease | 期刊论文 | Zhang Xiong;Yang Rui;Hu Bei Lei;Lu Pengcheng;Zhou Li Li;He Zhi Yong;Wu Hong Mei;Zhu Jian Hong |
| 5 | Mitochondrial DNA variants modulate genetic susceptibility to Parkinson's disease in Han Chinese | 期刊论文 | Wu Hong Mei;Li Ting;Wang Zhen Feng;Huang Shi Shi;Shao Zi Qiang;Wang Ke;Zhong Hai Qing;Chen Song Fang;Zhang Xiong;Zhu Jian Hong |
| 6 | N-acetylcysteine negatively regulates Notch3 and its malignant signaling | 期刊论文 | Zhang Xiong;Wang Ya-Nan;Zhu Juan-Juan;Liu Xue-Xia;You Hui;Gong Mei-Ying;Zou Ming;Cheng Wen-Hsing;Zhu Jian-Hong |
| 7 | SLC6A4 Repeat and Single-Nucleotide Polymorphisms Are Associated With Depression and Rest Tremor in Parkinson's Disease: An Exploratory Study | 期刊论文 | Wang Jian Yong;Fan Qian Ya;He Jia Hui;Zhu Shi Guo;Huang Chen Ping;Zhang Xiong;Zhu Jian Hong |
| 8 | Meta-analysis of brain iron levels of Parkinson's disease patients determined by postmortem and MRI measurements | 期刊论文 | Wang Jian-Yong;Zhuang Qing-Qing;Zhu Lan-Bing;Zhu Hui;Li Ting;Li Rui;Chen Song-Fang;Huang Chen-Ping;Zhang Xiong;Zhu Jian-Hong |
| 9 | Nuclear selenoproteins and genome maintenance | 期刊论文 | Zhang Xiong;Zhang Li;Zhu Jian-Hong;Cheng Wen-Hsing |
| 10 | Selenoprotein T Promotes Proliferation and G1-to-S Transition in SK-N-SH Cells: Implications in Parkinson's Disease. | 期刊论文 | Shao Zi Qiang;Zhang Xiong;Fan Hui Hui;Wang Xiao Shuang;Wu Hong Mei;Zhang Li;Cheng Wen Hsing;Zhu Jian Hong |
| 11 | Association analyses of variants of SIPA1L2, MIR4697, GCH1, VPS13C, and DDRGK1 with Parkinson's disease in East Asians | 期刊论文 | Zou Ming;Li Rui;Wang Jian Yong;Wang Ke;Wang Ya Nan;Li Yang;Ji Fei Xue;Sun Sheng Nan;Huang Shi Shi;Fan Hui Hui;Huang Chen Ping;Zhang Xiong;Zhu Jian Hong |
| 12 | A homozygous mutation of alanyl-transfer RNA synthetase 2 in a patient of adult-onset leukodystrophy: A case report and literature review | 期刊论文 | Wang Jian Yong;Chen Song Fang;Zhang Hong Qiu;Wang Meng Yan;Zhu Jian Hong;Zhang Xiong |
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