基于趋化因子/BMP-2骨再生材料的构建及其协同促进成骨机制

31470924
2014
C1002.生物材料与生物效应
袁媛
面上项目
教授
华东理工大学
80万元
机制;促进成骨;趋化因子;骨形态发生蛋白-2;引导骨组织再生
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Surface Topography Regulates Osteogenic Differentiation of MSCs via Crosstalk between FAK/MAPK and ILK/beta-Catenin Pathways in a Hierarchically Porous Environment 期刊论文 Niu Haoyi;Lin Dan;Tang Wei;Ma Yifan;Duan Bing;Yuan Yuan;Liu Changsheng
2 MBG scaffolds containing chitosan microspheres for binary delivery of IL-8 and BMP-2 for bone regeneration 期刊论文 Cai Lisha;Lin Dan;Chai Yanjun;Yuan Yuan;Liu Changsheng
3 PEGylated poly(glycerol sebacate)-modified calcium phosphate scaffolds with desirable mechanical behavior and enhanced osteogenic capacity 期刊论文 Ma Yifan;Zhang Wenjing;Wang Zihao;Wang Zi;Xie Qing;Niu Haoyi;Guo Han;Yuan Yuan;Liu Changsheng
4 Urethane-based low-temperature curing, highly-customized and multifunctional poly(glycerol sebacate)-co-poly(ethylene glycol) copolymers 期刊论文 Wang Zihao;Ma Yifan;Wang YanXiang;Liu Yutong;Chen Kai;Wu Zihan;Yu Shuang;Yuan Yuan;Liu Changsheng
5 Magnesium modification of a calcium phosphate cement alters bone marrow stromal cell behavior via an integrin-mediated mechanism 期刊论文 Jing Zhang; Xiaoyu Ma; Dan Lin; Hengsong Shi; Yuan Yuan; Wei Tang; Huanjun Zhou; Han Guo; Jiangchao Qian; Changsheng Liu
6 Strontium attenuates rhBMP-2-induced osteogenic differentiation via formation of Sr-rhBMP-2 complex and suppression of Smad-dependent signaling pathway 期刊论文 Zhang Wenjing;Tian Yu;He Hongyan;Chen Rui;Ma Yifan;Guo Han;Yuan Yuan;Liu Changsheng
7 Rapid initiation of guided bone regeneration driven by spatiotemporal delivery of IL-8 and BMP-2 from hierarchical MBG-based scaffol 期刊论文 Lin D;Chai YJ;Ma YF;Duan B;Yuan Y;Liu CS
8 Microporous density-mediated response of MSCs on 3D trimodal macro/micro/nano-porous scaffolds via fibronectin/integrin and FAK/MAPK signaling pathways 期刊论文 Duan Bing;Niu Haoyi;Zhang Wenjing;Ma Yifan;Yuan Yuan;Liu Changsheng
9 一种多参数可调控的聚癸二酸甘油酯/介孔生物玻璃复合支架的制备与性能表征 会议论文 林丹;袁媛
10 Bioinspired trimodal macro/micro/nano-porous scaffolds loading rhBMP-2 for complete regeneration of critical size bone defect 期刊论文 Tang Wei;Lin Dan;Yu Yuanman;Niu Haoyi;Guo Han;Yuan Yuan;Liu Changsheng
11 高强度仿生大孔/微孔/介孔三级结构介孔生物玻璃支架固载rhBMP-2用于临界尺寸骨缺损的完全修复 会议论文 林丹;袁媛
12 异氰酸酯交联聚乙二醇-聚癸二酸甘油酯生物弹性体及其制备方法和应用 专利 刘昌胜;袁媛;马一帆;王子豪
13 A poly(glycerol sebacate)-coated mesoporous bioactive glass scaffold with adjustable mechanical strength, degradation rate, controlled-release and cell behavior for bone tissue engineering 期刊论文 Dan Lin; Kai Yang; Wei Tang; Yutong Liu; Yuan Yuan; Changsheng Liu
14 Calcium ion-induced formation of beta-sheet/-turn structure leading to alteration of osteogenic activity of bone morphogenetic protein-2 期刊论文 Wenjing Zhang; Hongyan He; Yu Tian; Qi Gan; Jing Zhang; Yuan Yuan; Changsheng Liu
15 Facilitated receptor-recognition and enhanced bioactivity of bone morphogenetic protein-2 on magnesium-substituted hydroxyapatite surface 期刊论文 Huang Baolin;Yuan Yuan;Li Tong;Ding Sai;Zhang Wenjing;Gu Yuantong;Liu Changsheng
16 RhBMP-2 loaded MBG/PEGylated poly(glycerol sebacate) composite scaffolds for rapid bone regeneration 期刊论文 Chai Yanjun;Lin Dan;Ma Yifan;Yuan Yuan;Liu Changsheng
17 人骨形态发生蛋白-2复合材料及其制备方法和应用 专利 刘昌胜;林丹;柴延军;袁媛
18 MBG-Modified beta-TCP Scaffold Promotes Mesenchymal Stem Cells Adhesion and Osteogenic Differentiation via a FAK/MAPK Signaling Pathway 期刊论文 Liu Yutong;Ma Yifan;Zhang Jing;Xie Qing;Wang Zi;Yu Shuang;Yuan Yuan;Liu Changsheng
19 一种介孔生物玻璃/聚癸二酸甘油酯复合支架及其制备方法和应用 专利 刘昌胜;林丹;杨凯;袁媛
20 Localization and promotion of recombinant human bone morphogenetic protein-2 bioactivity on extracellular matrix mimetic chondroitin sulfate-functionalized calcium phosphate cement scaffolds 期刊论文 Huang Baolin;Wu Zihan;Ding Sai;Yuan Yuan;Liu Changsheng
21 "Bioactivation of Calcium Phosphate Cement by Growth Factors and Their Applications" in "Developments and Applications of Calcium Phosphate Bone Cements" 专著 袁媛
22 "Bioactivation of Calcium Phosphate Cement by Growth Factors and Their Applications" in "Developments and Applications of Calcium Phosphate Bone Cements" 专著 袁媛
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