智能型石墨烯/光敏剂/CpG纳米光致免疫复合药物的构建及其介导的高效抗肿瘤作用研究

81471785
2014
H2808.纳米医学
吴春惠
面上项目
副教授
电子科技大学
70万元
光敏剂;功能化纳米石墨烯;树突状细胞;肿瘤免疫治疗;寡核苷酸;CpG
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 一种用于肿瘤原位可视化治疗的核壳型纳米药物及其制备方法 专利 吴春惠;官晓天;田原;刘秋月;徐继明;张映雪;李顺;秦翔;杨红;刘贻尧
2 Mitochondria-targeted pegylatednanographene for enhanced cancer photodynamic therapy 会议论文 Lianhui Wang;Xiaotian Guan;Yuan Tian;Chunhui Wu
3 Folate-functionalized magnetic-mesoporous silica nanoparticles for drug/gene codelivery to potentiate the antitumor efficacy 期刊论文 Tingting Li;Xue Shen;Yue Geng;Zhongyuan Chen;Li Li;Shun Li;Hong Yang;Chunhui Wu;Hongjuan Zeng;Yiyao Liu
4 Gd/Photosensitizer dural conjugated graphene quantum dots for magnetic resonance/photoacoustic bimodal imaging-guided phototherapy 会议论文 Xiaotian Guan;Yuan Tian;Qiuyue Liu;Chunhui Wu;Shun Li;Xiang Qin;Hong Yang;Yiyao Liu
5 Chemo-photodynamic combined gene therapy and dual-modal cancer imaging achieved by pH-responsive alginate/chitosan multilayer-modified magnetic mesoporous silica nanocomposites 期刊论文 Hong Yang;Yin Chen;Zhongyuan Chen;Yue Geng;Xiaoxue Xie;Xue Shen;Tingting Li;Shun Li;Chunhui Wu;Yiyao Liu
6 一种线粒体靶向的纳米光敏免疫复合药物及其制备方法和应用 专利 吴春惠;王莲慧;田原;官晓天;刘秋月;刘贻尧;杨红;曾红娟
7 Photosensitizer-assembled PEGylated graphene-copper sulfide nanohybrids as a synergistic near-infrared phototherapeutic agent 期刊论文 Chunhui Wu;Anni Zhu;Dan Li;Lianhui Wang;Hong Yang;Hongjuan Zeng;Yiyao Liu
8 Engineered nanoformulation based on graphene/nanoparticle hybrids for cancer combination phototherapy 会议论文 Chunhui Wu;Qiuyue Liu;Yingxue Zhang;Jiming Xu;Hong Yang;Yiyao Liu
9 Irinotecan/IR-820 co-loaded hollow mesoporous silica nanoparticles as a platform for combinational chemotherapy and photothermal therapy of tumor 期刊论文 Tingting Li;Xue Shen;Xiaoxue Xie;Zhongyuan Chen;Shun Li;Xiang Qin;Hong Yang;Chunhui Wu;Yiyao Liu
10 Co-delivery of photosensitizer and toll-like receptor ligands via pH triggered charge-reversal polyelectrolyte-functionalized graphene for enhanced cancer photoimmunotherapy, 会议论文 Yuan Tian;Xiaotian Guan;Lianhui Wang;Chunhui Wu;Hong Yang;Yiyao Liu
11 Luminescent/magnetic hybrid PLGA-based nanocomposites: a smart nanocarrier system for targeted codelivery and dual-modality imaging in cancer theranostics 期刊论文 Xue Shen;Tingting Li;Zhongyuan Chen;Yue Geng;Xiaoxue Xie;Shun Li;Hong Yang;Chunhui Wu;Yiyao Liu
12 Photoactive targeted hybrid nanoassemblies for cancer combined photo/chemotherapy 会议论文 Qiuyue Liu;Jiming Xu;Yingxue Zhang;Chunhui Wu
13 Graphene quantum dots based nanotheraosics for magnetic resonance imaging-guided tumor phototherapy 会议论文 Chunhui Wu;Xiaotian Guan;Jiming Xu;Yingxue Zhang;Qiuyue Liu;Hong Yang;Yiyao Liu
14 Magnetic mesoporous silica nanoparticles co-delivering doxorubicin and VEGF siRNA for cervical cancer targeting therapy and MR imaging 会议论文 Tingting Li;Xue Shen;Chengchen Zhang;Hong Yang;Chunhui Wu;Yiyao Liu
15 基于石墨烯/金纳米星光敏复合物的高效光疗及其光声成像研究 会议论文 吴春惠;王莲慧;李丹;田原;官晓天;杨红;刘贻尧
16 Prospect of Engineered Graphene-Based Theragnostic Nanoformulation for Cancer Precise Treatment 会议论文 Chunhui Wu;Lianhui Wang;Dan Li;Xiaotian Guan;Yuan Tian;Hong Yang;Yiyao Liu
17 Near-Infrared light responsive graphene based nanocomposites for synergistic cancer phototherapy 会议论文 Chunhui Wu;Anni Zhu;Dan Li;Lianhui Wang;Hong Yang;Yiyao Liu
18 Construction of graphene-gold nanohybrids for tumor near-infrared combined phototherapy 会议论文 Dan Li;Lianhui Wang;Anni Zhu;Chunhui Wu;Hong Yang;Yiyao Liu
19 Charge-reversal functionalized PLGA nanobubbles as theranostic agents for ultrasonic imaging-guided combination therapy 期刊论文 Hong Yang;Xue Shen;Jie Yan;Xiaoxue Xie;Zhongyuan Chen;Tingting Li;Shun Li;Xiang Qin;Chunhui Wu;Yiyao Liu
20 Single wavelength light-mediated, synergistic bimodal cancer photoablation and amplified photothermal performance by graphene/gold nanostar/photosensitizer theranostics 期刊论文 Chunhui Wu;Dan Li;Lianhui Wang;Xiaotian Guan;Yuan Tian;Hong Yang;Shun Li;Yiyao Liu
21 Multifunctional core/shell nanoparticles cross-linked polyetherimide-folic acid as efficient Notch-1 siRNA carrier for targeted killing of breast cancer 期刊论文 Hong Yang;Ying Li;Tingting Li;Min Xu;Yin Chen;Chunhui Wu;Xitong Dang;Yiyao Liu
22 Chitosan hybrid nanoparticles as a theranostic platform for targeted doxorubicin/VEGF shRNA codelivery and dual-modality fluorescence imaging 期刊论文 Hong Yang;Min Xu;Shun Li;Xue Shen;Tingting Li;Jie Yan;Chengchen Zhang;Chunhui Wu;Hongjuan Zeng;Yiyao Liu
23 Multifunctional PLGA nanobubbles as theranostic agents: combining doxorubicin and P-gp siRNA co-delivery into human breast cancer cells and ultrasound cellular imaging 期刊论文 Hong Yang;Liwei Deng;Tingting Li;Xue Shen;Jie Yan;Liangming Zuo;Chunhui Wu;Yiyao Liu
24 近红外光猝发的线粒体靶向型纳米复合物介导的光疗/免疫联合抗肿瘤研究 会议论文 吴春惠;田原;官晓天;刘秋月;杨红;刘贻尧
25 "Triple-punch" anticancer strategy mediated by near-infrared photosensitizer/CpG oligonucleotides dual-dressed and mitochondria-targeted nanographene 期刊论文 Chunhui Wu;Lianhui Wang;Yuan Tian;Xiaotian Guan;Qiuyue Liu;Shun Li;Xiang Qin;Hong Yang;Yiyao Liu
26 Rational design of multifunctional polymeric micelles with stimuli-responsive for imaging-guided combination cancer therapy 期刊论文 Hong Yang;Chengchen Zhang;Tingting Li;Xue Shen;Zhongyuan Chen;Xiaoxue Xie;Shun Li;Xiang Qin;Chunhui Wu;Yiyao Liu
27 Polyetherimide-grafted Fe3O4@SiO2 nanoparticles as theranostic agents for simultaneous VEGF siRNA delivery and magnetic resonance cell imaging 期刊论文 Tingting Li;Xue Shen;Yin Chen;Chengchen Zhang;Jie Yan;Hong Yang;Chunhui Wu;Hongjun Zeng;Yiyao Liu
28 一种碳量子点的制备方法及其应用 专利 刘贻尧;徐敏;杨红;吴春惠;曾红娟
29 Synergistic anticancer activity of photo- and chemoresponsive nanoformulation based on polylysine-functionalized graphene 期刊论文 Chunhui Wu;Qiuming He;Anni Zhu;Dan Li;Min Xu;Hong Yang;Yiyao Liu
30 Synergistic cancer photoablation and amplified photothermal performance by graphene/gold nanostar/photosensitizer theranostics 会议论文 Chunhui Wu;Dan Li;Lianhui Wang;Xiaotian Guan;Yuan Tian;Hong Yang;Yiyao Liu
31 "Triple-punch" anticancer strategy mediated by near-infrared photosensitizer/CpG oligonucleotides dual-dressed and mitochondria-targeted nanographene 期刊论文 Chunhui Wu;Lianhui Wang;Yuan Tian;Xiaotian Guan;Qiuyue Liu;Shun Li;Xiang Qin;Hong Yang;Yiyao Liu
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