EGFR协同丙酮酸激酶M2调控内毒素血症中有氧糖酵解的相关分子机制研究
81873951
2018
H1601.脓毒症
唐靖
面上项目
教授
广东医科大学
57万元
丙酮酸激酶M2;细胞代谢;有氧糖酵解;表皮生长因子;内毒素血症
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Sorafenib inhibits LPS-induced inflammation by regulating Lyn-MAPK-NF-kB/AP-1 pathway and TLR4 expression | 期刊论文 | Xiaolian Li;Mingkun Xu;Jiaojiao Shen;Yuqin Li;Shaoping Lin;Min Zhu;Qiongni Pang;Xiujuan Tan;Jing Tang |
| 2 | METTL3 mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling | 期刊论文 | Shuhua Luo;Chaoxiong Liao;Lina Zhang;Chunxiu Ling;Xuedi Zhang;Pengyun Xie;Guomei Su;Zhanghui Chen;Liangqing Zhang;Tianwen Lai;Jing Tang |
| 3 | Erlotinib protests against LPS-induced parthanatos through inhibiting macrophage surface TLR4 expression | 期刊论文 | Xue Qiong;Liu Xiaolei;Chen Cuiping;Zhang Xuedi;Xie Pengyun;Liu Yupin;Zhou Shuangnan;Tang Jing |
| 4 | Remimazolam Protects Against LPS-Induced Endotoxicity Improving Survival of Endotoxemia Mice | 期刊论文 | Xiaolei Liu;Shaoping Lin;Yiyue Zhong;Jiaojiao Shen;Xuedi Zhang;Shuhua Luo;Li Huang;Liangqing Zhang;Shuangnan Zhou;Jing Tang |
| 5 | Propofol Upregulates MicroRNA-30b to Inhibit Excessive Autophagy and Apoptosis and Attenuates Ischemia/Reperfusion Injury In Vitro and in Patients | 期刊论文 | Zhiqi Lu;Jiaojiao Shen;Xubin Chen;Zhihua Ruan;Weihua Cai;Shuyun Cai;Minjun Li;Yuhui Yang;Jian Mo;Guixi Mo;Yan Lu;Jing Tang;Liangqing Zhang |
| 6 | Macrophage ICAM-1 functions as a regulator of phagocytosis in LPS induced endotoxemia | 期刊论文 | Zhong Hanhui;Lin Haitao;Pang Qiongni;Zhuang Jinling;Liu Xiaolei;Li Xiaolian;Liu Jinghua;Tang Jing |
| 7 | Propofol inhibits parthanatos via ROS-ER-calcium-mitochondria signal pathway in vivo and vitro | 期刊论文 | Zhong Hanhui;Song Rui;Pang Qiongni;Liu Yawei;Zhuang Jinling;Chen Yeming;Hu Jijie;Hu Jian;Liu Youtan;Liu Zhifeng;Tang Jing |
| 8 | Propofol postconditioning ameliorates hypoxia/reoxygenation induced H9c2 cell apoptosis and autophagy via upregulating forkhead transcription factors under hyperglycemia | 期刊论文 | Rong-Hui Han;He-Meng Huang;Hong Han;Hao Chen;Fei Zeng;Xiang Xie;Dan-Yong Liu;Yin Cai;Zheng-Yuan Xia;Jing Tang |
| 9 | EGFR signaling augments TLR4 cell surface expression and function in macrophages via regulation of Rab5a activation (vol 33, pg 451, 2020) | 期刊论文 | Jing Tang;Bowei Zhou;Melanie J Scott;Linsong Chen;Dengming Lai;Erica K Fan;Yuehua Li;Qiang Wu;Timothy R Billiar;Mark A Wilson;Ping Wang;Jie Fan |
| 10 | Incidence, Risk Factors, and Attributable Mortality of Catheter-Related Bloodstream Infections in the Intensive Care Unit After Suspected Catheters Infection: A Retrospective 10-year Cohort Study | 期刊论文 | Zhong Yiyue;Zhou Limin;Liu Xiaolei;Deng Liehua;Wu Ruona;Xia Zhengyuan;Mo Guixi;Zhang Liangqing;Liu Zhifeng;Tang Jing |
| 11 | EGFR tyrosine kinase activity and Rab GTPases coordinate EGFR trafficking to regulate macrophage activation in sepsis | 期刊论文 | Xuedi Zhang;Cuiping Chen;Chunxiu Ling;Shuhua Luo;Ziying Xiong;Xiaolei Liu;Chaoxiong Liao;Pengyun Xie;Youtan Liu;Liangqing Zhang;Zhanghui Chen;Zhifeng Liu;Jing Tang |
| 12 | EGFR promotes the apoptosis of CD4+ T lymphocytes through TBK1/Glut1 induced Warburg effect in sepsis | 期刊论文 | Li Huang;Xuedi Zhang;Junyu Fan;Xiaolei Liu;Shuhua Luo;Dianqing Cao;Youtan Liu;Zhengyuan Xia;Hanhui Zhong;Cuiping Chen;Liangqing Zhang;Zhifeng Liu;Jing Tang |
| 13 | Effects of stellate ganglion block on early brain injury in patients with subarachnoid hemorrhage: a randomised control trial | 期刊论文 | Zhang Jian;Nie Ying;Pang Qiongni;Zhang Xubiao;Wang Qianting;Tang Jing |
| 14 | Interplay between RAGE and TLR4 Regulates HMGB1-Induced Inflammation by Promoting Cell Surface Expression of RAGE and TLR4 | 期刊论文 | Hanhui Zhong;Xiaolian Li;Shuangnan Zhou;Ping Jiang;Xiaolei Liu;Mingwen Ouyang;Ying Nie;Xinying Chen;Liangqing Zhang;Youtan Liu;Tao Tao;Jing Tang |
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