TLR5及NAIP5/NLRC4炎症小体介导梅毒螺旋体鞭毛蛋白致炎反应的分子机制研究

81471576
2014
H1104.炎症、感染与免疫
吴移谋
面上项目
教授
南华大学
73万元
鞭毛蛋白;炎症小体;Toll样受体;梅毒螺旋体
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 梅毒螺旋体鞭毛蛋白与其受体相互作用的研究 会议论文 徐嫚;谢亚锋;谭满意;郑康;吴移谋
2 梅毒螺旋体FlaB3致炎作用的分子机制初步研究 会议论文 徐嫚;谢亚锋;谭满意;郑康;吴移谋
3 Treponema pallidum flagellin FlaA2 induces IL-6 secretion in THP-1 cells via the Toll-like receptor 2 signaling pathway. 期刊论文 Xie Yafeng;Xu Man;Xiao Yongjian;Liu Zhuoran;Jiang Chuanhao;Kuang Xingxing;Wang Chuan;Wu Haiying;Peng Jing;Li Chun;Wang Yu;Liu Huaming;Liu Bin;Zhang Xiaotuan;Zhao Feijun;Zeng Tiebing;Liu Shuangquan;Wu Yimou
4 A novel ELISA using a recombinant outer membrane protein, rTp0663, as the antigen for serological diagnosis of syphilis. 期刊论文 Xu Man;Xie Yafeng;Jiang Chuanhao;Xiao Yongjian;Kuang Xingxing;Zhao Feijun;Zeng Tiebing;Liu Shuangquan;Liang Mingxing;Li Li;Wang Chuan;Wu Yimou
5 Evaluation of FlaB1, FlaB2, FlaB3, and Tp0463 of Treponema pallidum for serodiagnosis of syphilis. 期刊论文 Jiang Chuanhao;Xiao Jinhong;Xie Yafeng;Xiao Yongjian;Wang Chuan;Kuang Xingxing;Xu Man;Li Ranhui;Zeng Tiebing;Liu Shuanquan;Yu Jian;Zhao Feijun;Wu Yimou
6 Development and Evaluation of a Loop-Mediated Isothermal Amplification Assay for the Detection of Treponema pallidum DNA in the Peripheral Blood of Secondary Syphilis Patients. 期刊论文 Xiao Yongjian;Xie Yafeng;Xu Man;Liu Shuangquan;Jiang Chuanhao;Zhao Feijun;Zeng Tiebing;Liu Zhuoran;Yu Jian;Wu Yimou
7 Screening and identification of immunoactive FlaB protein fragments of Treponema pallidum for the serodiagnosis of syphilis 期刊论文 Manyi Tan;Man Xu;Yafeng Xie;Yimou Wu;Feijun Zhao;Tiebing Zeng;Chuanhao Jiang
8 CpG-modified plasmid DNA encoding FlaB3 inhibits dissemination of Treponema pallidum in C57BL/6 mice 会议论文 郑康;徐嫚;吴移谋
9 梅毒螺旋体鞭毛蛋白诱导THP-1细胞表达促炎细胞因子的分子机制 会议论文 徐嫚;吴移谋
10 Treponema pallidum flagellins elicit proinflammatory cytokines from human monocytes via TLR5 signaling pathway. 期刊论文 Xu Man;Xie Yafeng;Jiang Chuanhao;Xiao Yongjian;Kuang Xingxing;Wen Yating;Tan Yuan;Tan Manyi;Zhao Feijun;Zeng Tiebing;Wu Yimou
11 梅毒螺旋体鞭毛蛋白的致炎分子机制及免疫保护作用初步研究 会议论文 徐嫚;郑康;谢亚锋;谭满意;吴移谋
12 梅毒螺旋体鞭毛蛋白经TLR5/MAPK/NF-κB通路诱导HaCaT细胞表达MMP-9和MMP-13 会议论文 蒋传好;徐嫚;谢亚锋;旷星星;谭满意;吴移谋
13 Molecular Subtyping and Surveillance of Resistance Genes In Treponema pallidum DNA From Patients With Secondary and Latent Syphilis in Hunan, China. 期刊论文 Xiao Yongjian;Liu Shuangquan;Liu Zhuoran;Xie Yafeng;Jiang Chuanhao;Xu Man;Zhao Feijun;Zeng TieBing;Yu Jian;Wu Yimou
14 Diagnostic value of recombinant Tp0821 protein in serodiagnosis for syphilis. 期刊论文 Xie Y;Xu M;Wang C;Xiao J;Xiao Y;Jiang C;You X;Zhao F;Zeng T;Liu S;Kuang X;Wu Y
15 Treponema pallidum flagellins stimulate MMP-9 and MMP-13 expression via TLR5 and MAPK/NF-kappaB signaling pathways in human epidermal keratinocytes. 期刊论文 Jiang Chuanhao;Xu Man;Kuang Xingxing;Xiao Jinhong;Tan Manyi;Xie Yafeng;Xiao Yongjian;Zhao Feijun;Wu Yimou
16 Immunogenicity and protective efficacy against Treponema pallidum in New Zealand rabbits immunized with plasmid DNA encoding flagellin. 期刊论文 Zheng Kang;Xu Man;Xiao Yongjian;Luo Haodang;Xie Yafeng;Yu Jian;Tan Manyi;Li Yumeng;Zhao Feijun;Zeng Tiebing;Wu Yimou
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