IL-6/STAT3通路双重抑制剂的发现及抗肿瘤药物设计

81202462
2012
H3407.药物设计与药物信息
赵承光
青年科学基金项目
副研究员
温州医科大学
23万元
白介素6;药物设计;炎症;信号转导子与转录活化子3;抗肿瘤药物
2013-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents 期刊论文 Yali Zhang, Chengguang Zhao, Wenfei He, et al|
2 Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism 期刊论文 Huey-Jen Lin|Shulin Yang|Jiayuh Lin|Guang Liang|
3 Rational combination of MEK inhibitor and the STAT3 pathway modulator for the therapy in K-Ras mutated pancreatic and colon cancer cells. 期刊论文 Li, Chenglong|Liang, Guang|Yang, Shulin|Lin, Jiayuh|
4 Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs). 期刊论文 Zhao, Chengguang|Liu, Zhiguo|Liang, Guang|
5 Synthesis and biological evaluation of a novel class of curcumin analogs as anti-inflammatory agents for prevention and treatment of sepsis in mouse model. 期刊论文 Shi, Dengjian|Li, Huameng|Liang, Guang|Yang, Shulin|
6 Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents. 期刊论文 Yali Zhang, Xin Jiang, Kesong Peng, et. al|
7 Synthesis and biological evaluation of acetylenic chalcones as novel anti-inflammatory agents. 期刊论文 Tang, Qinqin|Lu, Zhongqiu|Liang, Guang|Zhou, Jianmin|
8 Discovery and evaluation of asymmetrical monocarbonyl analogs of curcumin as anti-inflammatory agents. 期刊论文 Xiao, Bing|Liu, Zhiguo|Liang, Guang|Yang, Shulin|
9 Synthesis and Evaluation of a Series of Novel Asymmetrical Curcumin Analogs for the Treatment of Inflammation 期刊论文 Yali Zhang , Leping Zhao,Jianzhang Wu,et.al|
10 Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs). 期刊论文 Zhao, Chengguang|Liu, Zhiguo|Liang, Guang|
11 Promising curcumin-based drug design: mono-carbonyl analogues of curcumin (MACs). 期刊论文 Zhao, Chengguang|Liu, Zhiguo|Liang, Guang|
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