【21102084】没药烷吉酮衍生物的合成及其 H+/K+-ATP 酶抑制活性研究国家自然基金项目

没药烷吉酮衍生物的合成及其 H+/K+-ATP 酶抑制活性研究

项目批准号： 21102084

批准年份： 2011

学科分类： B0706.药物化学生物学

项目负责人：黄年玉

资助类别：青年科学基金项目

负责人职称：教授

依托单位：三峡大学

资助金额： 25万元

关键词：消化性溃疡;没药烷吉酮;药物分子设计;H+/K+-ATP酶抑制剂

起止时间： 2012-01-01到2014-12-31

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序号	标题	类型	作者
1	倍半萜型 H+/K+-ATP 酶抑制剂的设计与合成	会议论文	黄年玉\|
2	倍半萜型 H+/K+-ATP 酶抑制剂的设计与合成	期刊论文	陈雷, 汪鋆植, 黄年玉, 罗华军, 方胡彪, 但飞君\|
3	Crystal structure of (3S,Z)-3-hydroxy-3,6-dimethyl-2-(3-methylbutylidene)- 3,3a,7,7a-tetrahydrobenzofuran-4(2H)-one, C15H22O3	期刊论文	Hubiao Fang\|Lei Chen\|Nianyu Huang\|Junzhi Wang\|Zhaojiang Liao\|
4	Synthesis and H+/K+-ATPase Inhibitory Activity of 2-phenyl-6,7-dihydrobenzofuran-4(5H)-one Oxime Ether Derivatives	期刊论文	方胡彪\|金蕾\|翟伟宸\|宋玉蓉\|汪鋆植\|黄年玉\|
5	Bisabolangelone, a gastric H+/K+-ATPase inhibitor: homology modeling and docking study	期刊论文	Luo, Hua-Jun\|Wang, Jun-Zhi\|Deng, Wei-Qiao\|Huang, Nian-Yu\|Zou, Kun\|
6	Synthesis and Crystal Structure of (5-Hydroxy-6-methoxybenzofuran-3-yl)-(4-methoxyphenyl)methanone	期刊论文	HE Bi-Feng\|WEI Yong\|LI Xiao-Yan\|XIE Yong\|LUO Hua-Jun\|HUANG Nian-Yu\|DENG Wei-Qiao\|
7	An Efficient Solvent-Free Synthesis of bis(2- tetrahydrobenzofuranyl)alkanes catalyzed by H2SO4？SiO2	期刊论文	Fan Zhang\|LuLu Xiao\|Lei Jin\|Wenbin Wang\|Nian-Yu Huang\|
8	Synthesis and in Vitro Anti-ulcer Effect of Triazolo-methyl Tetrahydrobenzofuran Oxime Ether Derivatives	期刊论文	方胡彪\|金蕾\|曹成桥\|罗华军\|黄年玉\|
9	Estrogenic and Anti-estrogenic Activities of Hispolon from Phellinus lonicerinus (Bond.) Bond. et sing.	期刊论文	Junzhi Wang\|Fang Hu\|Youcheng Luo\|Huajun Luo\|Nianyu Huang\|Fan Cheng\|Zhangshuang Deng\|Weiqiao Deng\|Kun Zou\|
10	Facile and eco-friendly synthesis of bis(2-tetrahydrobenzofuranyl)alkane derivatives catalyzed by H2SO4？SiO2 under solvent-free conditions	期刊论文	Lei Jin\|Wenbin Wang\|Chengqiao Cao\|Nianyu Huang\|Junzhi Wang\|Kun Zou\|
11	Double directional adjusting estrogenic effect of naringin from Rhizoma drynariae (Gusuibu)	期刊论文	Guo, Dongyan\|Wang, Junzhi\|Wang, Xingqin\|Luo, Huajun\|Zhang, Hongqi\|Cao, Dan\|Chen, Lei\|Huang, Nianyu\|
12	Synthesis and Crystal Structure of N-methyl-N-((2-(p-tolyl)quinolin-4-yl)methyl)aniline	期刊论文	Wei Yong\|Cao Cheng-Qiao\|Jin Lei\|Huang Nian-Yu\|Zou Kun\|
13	Synthesis and Characterization of Triazole-linked Bistetrahydrobenzofuran Derivatives as Anti-ulcer Agents	期刊论文	Quan-Li Yang\|Chun-Xue Chen\|Wu Li\|Wan Liu\|Hu-Biao Fang\|Nian-Yu Huang\|
14	没药烷吉酮治疗痛经及机制研究	期刊论文	吴方方, 汪鋆植, 黄年玉, 张巧银, 罗华军, 邹坤, 金蕾, 吴晓娟\|
15	不同炮制方法对紫金砂中成分及活性的影响	期刊论文	周明星\|蒋刚\|李莉娥\|罗华军\|黄年玉\|汪鋆植\|
16	Crystal structure of (3R,6R,Z)-3-hydroxy-3,6-dimethyl-2-(3-methylbutylidene)hexahydrobenzofur an-4(2H)-one, C15H24O3	期刊论文	Zhang, Biao\|Tian, Shuangliang\|He, Xiong\|Yang, Jin\|Hou, Xueli\|Huang, Nianyu\|
17	Synthesis and Crystal Structure of (3S,4R,Z)-3,6-dimethyl-2-(3-methylbut-2-enylidene)-2,3,3a,4,7,7a-hexahyd robenzofuran-3,4-diol	期刊论文	Chen Lei\|Fang Hu-Biao\|Huang Nian-Yu\|Wang Jun-Zhi\|Zou Kun\|
18	(2S,3S,3aS,6S,7aR)-3-Hydroxy-2-[(2R,3S*)-3-isopropyloxiran-2-yl]-3,6- dimethyl-3,3a,5,6,7,7a-hexahydro-1-benzofuran-4(2H)-one	期刊论文	黄年玉\|
19	Synthesis, Structure and H+/K+-ATPase Inhibitory Activity of Novel Triazolyl Substituted Tetrahydrobenzofuran Derivatives via One-pot Three-component Click Reaction	期刊论文	Fang, Hubiao\|Jin, Lei\|Huang, Nianyu\|Wang, Junzhi\|Zou, Kun\|Luo, Zaigang\|
20	Synthesis, Structure Elucidation and H+/K+-ATPase Inhibitory Activity of Bisabolangelone Reduction Derivatives	期刊论文	Huang Nianyu\|Chen Lei\|Liao Zhaojiang\|Fang Hubiao\|Wang Junzhi\|Zou Kun\|
21	Synthesis and Crystal Structure of (Z)-2-Methyl-5,6-dihydrobenzo[d]thiazol-7(4H)-one O-Prop-2-yn-1-yl Oxime Derivatives	期刊论文	CAO Cheng-Qiao\|YAN Xi-Ming\|YANG Quan-Li\|LUO Hua-Jun\|Nianyu Huang\|
22	3-Acyl-5-hydroxybenzofuran derivatives as potential anti-estrogen breast cancer agents: A combined experimental and theoretical investigation	期刊论文	Li, Xiao-Yan\|He, Bi-Feng\|Luo, Hua-Jun\|Huang, Nian-Yu\|Deng, Wei-Qiao\|
23	Synthesis and Structure Elucidation of Novel Oxime Ether Type H+/K+-ATPase Inhibitors	期刊论文	金蕾\|方胡彪\|黄年玉\|汪鋆植\|邹坤\|
24	Synthesis, Structure and Gastric H+/K+-ATPase Inhibitory Activities of Bisabolonalone Hydrazone Carboxamides	期刊论文	金蕾\|陈雷\|罗华军\|郭志勇\|黄年玉\|邓伟侨\|
25	The H+/K+-ATPase inhibitory activities of Trametenolic acid B from Trametes lactinea (Berk.) Pat, and its effects on gastric cancer cells	期刊论文	Qiaoyin Zhang\|Nianyu Huang\|Junzhi Wang\|Huajun Luo\|Haibo He\|Mingruo Ding\|Wei-Qiao Deng\|Kun Zou\|
26	Synthesis and Crystal Structure of (E)-2-phenyl-6,7-dihydrobenzofuran-4(5H)-one O-cyanomethyl Oxime	期刊论文	金蕾\|方胡彪\|曹成桥\|黄年玉\|邹坤\|汪鋆植\|
27	Synthesis and in vitro Anti-breast Cancer Activity of Trametenolic acid B Derivatives	期刊论文	丁明若\|张巧银\|胡芳\|黄年玉\|汪鋆植\|
28	Synthesis and Crystal Structure of (5-Hydroxy-6-methoxybenzofuran-3-yl)-(4-methoxyphenyl)methanone	期刊论文	Bifeng He\|Yong Wei\|Xiaoyan Li\|Yong Xie\|Huajun Luo\|Nianyu Huang\|Weiqiao Deng\|

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