胰岛β细胞特异性敲除Cdc42对机体血糖稳态的影响及其机制研究

81760140
2017
H0706.胰岛生理调控与功能异常
邓柯玉
地区科学基金项目
教授
南昌大学
34万元
胰岛素分泌;血糖稳态;谷氨酰胺酶;胰岛beta细胞;细胞分裂调控蛋白42
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Human amniotic mesenchymal stem cells and their paracrine factors promote wound healing by inhibiting heat stress-induced skin cell apoptosis and enhancing their proliferation through activating PI3K/AKT signaling pathway 期刊论文 Li Jing-Yuan;Ren Kang-Kang;Zhang Wen-Jie;Xiao Ling;Wu Han-You;Liu Qian-Yu;Ding Ting;Zhang Xiang-Cheng;Nie Wen-Jia;Ke Yu;Deng Ke-Yu;Liu Quan-Wen;Xin Hong-Bo
2 Human amniotic mesenchymal stem cells-conditioned medium protects mice from high-fat diet-induced obesity. 期刊论文 Tan Hui-Lan;Guan Xiao-Hui;Hu Min;Wu Jie;Li Rong-Zhen;Wang Ling-Fang;Huang Hou-Da;Yu Zhen-Ping;Wang Xiao-Yu;Xiao Yun-Fei;Deng Ke-Yu;Xin Hong-Bo
3 Recruitment of monocytes and epigenetic silencing of intratumoral CYP7B1 primarily contribute to the accumulation of 27-hydroxycholesterol in breast cancer 期刊论文 Shi Shui Zhen;Lee Eun Joon;Lin Ying Jiong;Chen Lu;Zheng Huai Yu;He Xiang Qin;Peng Jing Yi;Noonepalle Satish K;Shull Austin Y;Pei Felix C;Deng Li Bin;Tian Xiao Li;Deng Ke Yu;Shi Huidong;Xin Hong Bo
4 Human amniotic stem cells-derived exosmal miR-181a-5p and miR-199a inhibit melanogenesis and promote melanosome degradation in skin hyperpigmentation, respectively. 期刊论文 Wang Xiao-Yu;Guan Xiao-Hui;Yu Zhen-Ping;Wu Jie;Huang Qi-Ming;Deng Ke-Yu;Xin Hong-Bo
5 Specific deletion of CDC42 in pancreatic β cells attenuates glucose-induced insulin expression and secretion in mice 期刊论文 Xiang-Qin He;Ning Wang;Juan-Juan Zhao;Dan Wang;Cai-Ji Wang;Lin Xie;Huai-Yu Zheng;Shui-Zhen Shi;Jing He;Jiliang Zhou;Hong-Bo Xin;Ke-Yu Deng
6 CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD(+)/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes. 期刊论文 Xie Lin;Wen Ke;Li Qian;Huang Cong-Cong;Zhao Jia-Le;Zhao Qi-Hang;Xiao Yun-Fei;Guan Xiao-Hui;Qian Yi-Song;Gan Lu;Wang Ling-Fang;Deng Ke-Yu;Xin Hong-Bo
7 A Cocktail-Inspired Male Birth Control Strategy with Physical/Chemical Dual Contraceptive Effects and Remote Self-Cleared Properties 期刊论文 Bao Weiwei;Xie Lin;Zeng Xuhui;Kang Hang;Wen Shiqi;Cui Ben;Li Wenting;Qian Yisong;Wu Jie;Li Ting;Deng Keyu;Xin Hong Bo;Wang Xiaolei
8 CD38 Deficiency Alleviates D-Galactose-lnduced Myocardial Cell Senescence Through NAD( )/Sirt1 Signaling Pathway 期刊论文 Wang Ling Fang;Cao Qing;Wen Ke;Xiao Yun Fei;Chen Ting Tao;Guan Xiao Hui;Liu Yu;Zuo Li;Qian Yi Song;Deng Ke Yu;Xin Hong Bo
9 Bone marrow cells are differentiated into MDSCs by BCC-Ex through down-regulating the expression of CXCR4 and activating STAT3 signalling pathway. 期刊论文 Liu Quan-Wen;Chen Yong;Li Jing-Yuan;Xiao Ling;Zhang Wen-Jie;Zhao Jia-Le;Gu Hao-Cheng;Wu Han-You;Zuo Guo-Si-Lang;Deng Ke-Yu;Xin Hong-Bo
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