颈部交感神经节P2受体参与糖尿病心交感神经病理损伤的机理研究
81560219
2015
H0911.神经-肌肉接头和肌肉疾病、自主神经疾病
李桂林
地区科学基金项目
教授
南昌大学
40万元
糖尿病心交感神经病变;P2受体;卫星胶质细胞;颈上神经节;星状神经节
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Lead exposure inhibits expression of SV2C through NRSF | 期刊论文 | Yang Meiyuan;Li Yaobin;Hu Lei;Luo Dan;Zhang Yi;Xiao Xue;Li Guilin;Zhang Lixia;Zhu Gaochun |
| 2 | The Inhibition by Guanfu Base A of Neuropathic Pain Mediated by P2Y(12) Receptor in Dorsal Root Ganglia | 期刊论文 | Zou Lifang;Yu Kehua;Fan Yang;Cao Suixia;Liu Shuangmei;Shi Liran;Li Lin;Yuan Huilong;Yang Runan;Yi Zhihua;Gao Yun;Li Guilin;Greffrath Wolfgang;Treede Rolf Detlef;Li Man;Xu Hong;Zhang Chunping;Liang Shangdong |
| 3 | Chronic lead exposure enhances the sympathoexcitatory response associated with P2X4 receptor in rat stellate ganglia | 期刊论文 | Zhu Gaochun;Chen Zhenying;Dai Bo;Zheng Chaoran;Jiang Huaide;Xu Yurong;Sheng Xuan;Guo Jingjing;Dan Yu;Liang Shangdong;Li Guilin |
| 4 | 颈部交感神经节P2X信号介导心肌缺血引发交感兴奋反应及其调节 | 奖励 | 梁尚栋;李桂林;刘双梅;高云 |
| 5 | Involvement of purinergic 2X(4) receptor in glycoprotein 120-induced pyroptosis in dorsal root ganglia | 期刊论文 | Zhao Shanhong;Zhou Yanhong;Fan Yang;Gong Yingxin;Yang Jingjian;Yang Runan;Li Lin;Zou Lifang;Xu Xiumei;Li Guilin;Liu Shuangmei;Zhang Chunping;Li Guodong;Liang Shangdong |
| 6 | LncRNAs在糖尿病神经血管病变中的研究进展 | 期刊论文 | 许玉荣;李桂林 |
| 7 | Knockdown the P2X3 receptor in the stellate ganglia of rats relieved the diabetic cardiac autonomic neuropathy | 期刊论文 | Sheng Xuan;Dan Yu;Dai Bo;Guo Jingjing;Ji Huihong;Zhang Xinge;Xie Zhi;Song Siqi;Pan Qiwen;Wang Jiayue;Liang Shangdong;Li Guilin |
| 8 | TRP离子通道在瘙痒中的作用及机制研究进展 | 期刊论文 | 郭晶晶;李桂林 |
| 9 | P2Y receptors in neuropathic pain. | 期刊论文 | Zhang Xinge;Li Guilin |
| 10 | 嘌呤受体在神经元和神经胶质细胞间信息传递中的作用 | 期刊论文 | 盛璇;李桂林 |
| 11 | P2Y12 shRNA treatment decreases SGC activation to relieve diabetic neuropathic pain in type 2 diabetes mellitus rats | 期刊论文 | Wang Shouyu;Wang Zilin;Li Lin;Zou Lifang;Gong Yingxin;Jia Tianyu;Zhao Shanhong;Yuan Huilong;Shi Liran;Liu Shuangmei;Wu Bing;Yi Zhihua;Liu Hui;Gao Yun;Li Guilin;Deussing Jan M;Li Man;Zhang Chunping;Liang Shangdong |
| 12 | LncRNA NONRATT021972 involved the pathophysiologic processes mediated by P2X(7) receptors in stellate ganglia after myocardial ischemic injury | 期刊论文 | Zou Lifang;Tu Guihua;Xie Wei;Wen Shiyao;Xie Qiuyu;Liu Shuangmei;Li Guilin;Gao Yun;Xu Hong;Wang Shouyu;Xue Yun;Wu Bing;Lv Qiulan;Ying Mofeng;Zhang Xi;Liang Shangdong |
| 13 | Effects of Baicalin on Diabetic Cardiac Autonomic Neuropathy Mediated by the P2Y12 Receptor in Rat Stellate Ganglia | 期刊论文 | Sheng Xuan;Wang Jiayue;Guo Jingjing;Xu Yurong;Jiang Huaide;Zheng Chaoran;Xu Zixi;Zhang Yuanruohan;Che Hongyu;Liang Shangdong;Zhu Gaochun;Li Guilin |
| 14 | Nanoparticle-Encapsulated Curcumin Inhibits Diabetic Neuropathic Pain Inv olvingtheP2Y12 Receptor in the Dorsal RootGanglia | 期刊论文 | Jia Tianyu;Rao Jingan;Zou Lifang;Zhao Shanhong;Yi Zhihua;Wu Bing;Li Lin;Yuan Huilong;Shi Liran;Zhang Chunping;Gao Yun;Liu Shuangmei;Xu Hong;Liu Hui;Liang Shangdong;Li Guilin |
| 15 | Long noncoding NONRATT021972 siRNA normalized abnormal sympathetic activity mediated by the upregulation of P2X7 receptor in superior cervical ganglia after myocardial ischemia. | 期刊论文 | Guihua Tu;Lifang Zou;Shuangmei Liu;Bing Wu;Qiulan Lv;Shouyu Wang;Yun Xue;Chunping Zhang;Zhihua Yi;Xi Zhang;Guilin Li;Shangdong Liang |
| 16 | Long noncoding RNA MRAK009713 is a novel regulator of neuropathic pain in rats. | 期刊论文 | Li Guilin;Jiang Huaide;Zheng Chaoran;Zhu Gaochun;Xu Yurong;Sheng Xuan;Wu Bing;Guo Jingjing;Zhu Shuanghua;Zhan Yuting;Lin Weijian;Ding Rui;Zhang Chunping;Liu Shuangmei;Zou Lifang;Yi Zhihua;Liang Shangdong |
| 17 | Osthole relieves diabetics cardiac autonomic neuropathy associated with P2X3 receptor in ratstellate ganglia | 期刊论文 | Wu Baoguo;Sheng Xuan;Xu Zixi;Zhang Yuanruohan;Dan Yu;Guo Jingjing;Peng Hao;Liang Shangdong;Li Guilin |
| 18 | Naringin Protects Against High Glucose-Induced Human Endothelial Cell Injury Via Antioxidation and CX3CL1 Downregulation. | 期刊论文 | Li Guilin;Xu Yurong;Sheng Xuan;Liu Hua;Guo Jingjing;Wang Jiayue;Zhong Qi;Jiang Huaide;Zheng Chaoran;Tan Mengxia;Rao Shenqiang;Yu Yanling;Gao Yun;Li Guodong;Liang Shangdong;Zhu Gaochun |
| 19 | LncRNA NONRATT021972 siRNA normalized the dysfunction of hepatic glucokinase through AKT signaling in T2DM rats | 期刊论文 | Miaomiao Song;Lifang Zou;Lichao Peng;Shuangmei Liu;Bing Wu;Zhihua Yi;Yun Gao;Chunping Zhang;Hong Xu;Yurong Xu;Mengxia Tang;Shouyu Wang;Yun Xue;Tianyu Jia;Shanhong Zhao;Shangdong Liang;Guilin Li |
| 20 | Involvement of P2Y12 receptor of stellate ganglion in diabetic cardiovascular autonomic neuropathy. | 期刊论文 | Guo Jingjing;Sheng Xuan;Dan Yu;Xu Yurong;Zhang Yuanruohan;Ji Huihong;Wang Jiayue;Xu Zixi;Che Hongyu;Li Guodong;Liang Shangdong;Li Guilin |
| 21 | Effects of chronic lead exposure on the sympathoexcitatory response associated with the P2X7 receptor in rat superior cervical ganglia | 期刊论文 | Zhu Gaochun;Dai Bo;Chen Zhenying;He Liyun;Guo Jingjing;Dan Yu;Liang Shangdong;Li Guilin |
| 22 | LncRNA uc.48+ siRNA improved diabetic sympathetic neuropathy in type 2 diabetic rats mediated by P2X7 receptor in SCG | 期刊论文 | Bing Wu;Chunping Zhang;Lifang Zou;Yucheng Ma;Kangyu Huang;Qiulan Lv;Xi Zhang;Shouyu Wang;Yun Xue;Zhihua Yi;Tianyu Jia;Shanhong Zhao;Shuangmei Liu;Hong Xu;Guilin Li;Shangdong Liang |
| 23 | Co-expression changes of lncRNAs and mRNAs in the cervical sympathetic ganglia in diabetic cardiac autonomic neuropathic rats. | 期刊论文 | Li Guilin;Sheng Xuan;Xu Yurong;Jiang Huaide;Zheng Chaoran;Guo Jingjing;Sun Shanshan;Yi Zhihua;Qin Shulan;Liu Shuangmei;Gao Yun;Zhang Chunping;Xu Hong;Wu Bing;Zou Lifang;Liang Shangdong;Zhu Gaochun |
| 24 | The effects of NONRATT021972 lncRNA siRNA on PC12 neuronal injury mediated by P2X(7) receptor after exposure to oxygen-glucose deprivation | 期刊论文 | Li Guilin;Zou Lifang;Xie Wei;Wen Shiyao;Xie Qiuyu;Gao Yun;Xu Changshui;Xu Hong;Liu Shuangmei;Wang Shouyu;Xue Yun;Wu Bing;Lv Qiulan;Ying Mofeng;Zhang Xi;Liang Shangdong |
| 25 | 长非编码核糖核酸MRAK009713小干扰RNA在制备神经病理痛药物中的应用 | 专利 | 李桂林;祝高春;梁尚栋;姜怀德;郑超然 |
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